Abstract: The present invention relates to a composition comprising 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl]-2-thiophene carboxyamide as an active ingredient, manufactured by a melt extrusion method. The composition according to the present invention has a wide variety of advantages such as securing dissolution rate and bioavailability of the active ingredient, improving absorption deviation depending on whether a patient has a meal or not, and securing stability during the manufacturing process. The present invention further provides a method which can manufacture the said composition.

Abstract: The present invention relates to a method for separating volatile substances, particularly iodine, diiodised aromatic compounds and/or mixtures thereof, from material mixtures containing said compounds. The invention further relates to a device for producing polyarylene sulphides, by means of which volatile substances, particularly iodine and diiodised aromatic compounds, can be separated from the polymers.

Abstract: The present invention relates to a method for separating volatile substances, particularly iodine, diiodized aromatic compounds and/or mixtures thereof, from material mixtures containing said compounds. The invention further relates to a device for producing polyarylene sulphides, by means of which volatile substances, particularly iodine and diiodized aromatic compounds, can be separated from the polymers.

Abstract: The present invention relates to polyarylene sulfide, in which a ratio of a peak area of a polymer chain of a second polyarylene sulfide having a lower molecular weight than the maximum peak molecular weight to a peak area of a polymer chain of a first polyarylene sulfide having a higher molecular weight than the maximum peak molecular weight is 1.3 or less in the molecular weight distribution of the polyarylene sulfide, as measured by gel permeation chromatography using polystyrene as a standard, and a preparation method thereof. This polyarylene sulfide exhibits excellent processability and generates no burrs (flashes) or the like, and can satisfactorily mold a product requiring high molding precision.

Abstract: Provided is an immunogenic composition comprising 13 different polysaccharide-protein conjugates. Each of the conjugates comprises a capsular polysaccharide prepared from a different serotype Streptococcus pneumoniae conjugated to a carrier protein, that is, 12 serotypes selected from the group consisting of 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F and serotype 2 or 9N. The immunogenic composition formulated into a vaccine comprising an aluminum-based adjuvant increases coverage with respect to pneumococcal diseases in infants and children.

Abstract: Provided is a polymer resin composition capable of providing an environmentally friendly biomass-containing synthetic resin which exhibits improved chemical resistance. Provided is a high heat resistant polymer resin composition having excellent chemical resistance, the composition including a polyester copolymer containing a residue of a dicarboxylic acid component containing terephthalic acid and a residue of a diol component containing dianhydrohexitol; one or more copolymers selected from the group consisting of an unsaturated nitrile-diene-based rubber-aromatic vinyl graft copolymer, an alkylmethacrylate-diene-based rubber-aromatic vinyl graft copolymer, and an alkylmethacrylate-silicone/alkylacrylate graft copolymer; and polytrimethylene terephthalate, and having 0.

Abstract: Provided are components for vehicles, electric/electronic products, home appliances, office equipments or household items, which are manufactured using a high heat resistant polymer resin composition capable of providing an environmentally friendly biomass-containing synthetic resin which exhibits improved chemical resistance.

Abstract: Disclosed is a method for producing proteins having factor VIII procoagulant activity in serum-free medium by in vitro culturing of mammalian cells, wherein the serum-free medium contains an inhibitor against the protease released from cultured cells. In accordance with this invention, the inhibitor can protect the cleavage of a target protein during cultivation and increase homogeneity of a target molecule, wherein the inhibitor can be a dextran sulfate. This invention also relates to a method of purifying target molecules from the culture medium containing both a target molecule and selected inhibitors by affinity chromatography.

Abstract: A preparation method of a polycyclohexylenedimethylene terephthalate resin according to the present invention includes the steps of injecting a titanium compound and a germanium compound as catalysts to a mixture of a diol compound and dicarboxylic acid under stirring and performing esterification reaction and polycondensation reaction, in which the titanium compound is injected in a titanium atom content of 20 ppm or less, based on the weight of the final polycyclohexylenedimethylene terephthalate resin. The preparation method of the polycyclohexylenedimethylene terephthalate resin according to the present invention can be used to prepare a polycyclohexylenedimethylene terephthalate resin that has excellent degree of polymerization, color and light reflectance and has remarkably improved heat stability, and it is suitable to use the polycyclohexylenedimethylene terephthalate resin according to the present invention as an LED housing material.

Abstract: Disclosed are a gonadotropin releasing hormone receptor antagonist and a pharmaceutical composition including the same, which can be useful in preventing or treating a sex hormone-related disease such as endometriosis, amenorrhea, irregular menstruation, uterine myoma, uterine fibroids, polycystic ovarian disease, lupus erythematous, hypertrichosis, precocious puberty, short stature, acne, alopecia, gonadal steroid-dependent neoplasms, gonadotropin-producing pituitary adenoma, sleep apnea, irritable bowel syndrome, premenstrual syndrome, benign prostatic hyperplasia, contraception, and infertility, as well as Alzheimer disease.

Abstract: Disclosed is a Madin-Darby canine kidney (MDCK)-derived cell line. The MDCK-derived cell line is derived from MDCK cells deposited under accession number ATCC CCL-34. The MDCK-derived cell line can be prepared by serum-free culture and suspension culture. Preferably, the MDCK-derived cell line has low or no tumorigenicity. The MDCK-derived cell line is preferably selected from MDCK Sky1023, MDCK Sky10234 and MDCK Sky3851. Further disclosed are a culture method for growing the MDCK-derived cells and a method for producing a vaccine virus using the MDCK-derived cells.

Abstract: Disclosed is a method for producing proteins having factor VIII procoagulant activity in serum-free medium by in vitro culturing of mammalian cells, wherein the serum-free medium contains an inhibitor against the protease released from cultured cells. In accordance with this invention, the inhibitor can protect the cleavage of a target protein during cultivation and increase homogeneity of a target molecule, wherein the inhibitor can be a dextran sulfate. This invention also relates to a method of purifying target molecules from the culture medium containing both a target molecule and selected inhibitors by affinity chromatography.

Abstract: The various embodiments of the invention relate to recyclable polyarylene sulfide that may exhibit and maintain excellent mechanical properties, particularly does not exhibit decrease in melt viscosity when it is molten, and thus exhibit little deterioration of mechanical properties, and a method for preparing the dame. The polyarylene sulfide has initial melt viscosity measured at 300° C. of 300 to 6000 poise, and melt viscosity after heat treated and molten at 300° C., equal to or greater than the initial melt viscosity.

Abstract: Disclosed are a copolymeric polyester resin composition having outstanding color stability (transparency) and a production method therefor. The copolymeric polyester resin composition comprises: between 95 and 99.99 percent by weight of a copolymeric polyester resin having a structure which is obtained by the copolymerization of a dicarboxylic acid component and a diol component that comprises isosorbide, and in which there is repetition of a dicarboxylic acid moiety derived from the dicarboxylic acid component and a diol moiety derived from the diol component; and between 0.01 and 5 percent by weight of an antioxidant selected from the group consisting of hindered phenol-based antioxidants, phosphite-based antioxidants, thioether-based antioxidants and mixtures thereof.

Abstract: Disclosed is a method for preparing fatty acid alkyl ester for bio-diesel fuels by reacting a raw material containing fat with water to prepare fatty acid, and then reacting the prepared fatty acid with alcohol. The method for preparing fatty acid alkyl ester for bio-diesel fuels includes the steps of: preparing fatty acid and glycerin by an hydrolysis reaction of a raw material containing fat and water at the temperature of 200 to 280° C. and the pressure of 30 to 80 bar; carrying out a phase separation of the fatty acid and the glycerin; and carrying out an esterification reaction of the separated fatty acid and alcohol at the temperature of 200 to 350° C. and the pressure of atmospheric pressure to 35 bar.

Abstract: The present invention relates to a polymer resin composition that is capable of providing an environmentally friendly biomass-containing synthetic resin having improved chemical resistance. The present invention provides a polymer resin composition including: a polyester copolymer including a residue of a dicarboxylic acid component containing terephthalic acid, and a residue of a diol component including dianhydrohexitol; and one or more copolymers selected from the group consisting of an unsaturated nitrile-diene-based rubber-aromatic vinyl graft copolymer, an alkyl methacrylate-diene-based rubber-aromatic vinyl graft copolymer, and an alkyl methacrylate-silicone/alkyl acrylate graft copolymer, and which has a tensile strength loss defined in the following Equation 1 ranging from 0.5 to 30%.

Abstract: A chemical resistant polymer resin composition for an overhead console includes a polyester resin including a residue of a dicarboxylic acid component containing terephthalic acid and a residue of a diol component containing 5 to 60 mol % of isosorbide, 5 to 80 mol % of cyclohexanedimethanol, and a residual amount of other diol compounds; polycarbonate; and an unsaturated nitrile-aromatic vinyl-alkylacrylate graft copolymer based on the total weight of the polyester resin, polycarbonate, and unsaturated nitrile-aromatic vinyl-alkylacrylate graft copolymer. The composition further includes 0.1 to 10 parts by weight of a weather resistant additive, based on 100 parts by weight of the polyester resin, polycarbonate, and unsaturated nitrile-aromatic vinyl-alkylacrylate graft copolymer.

Abstract: Disclosed is a method for preparing a polyester resin, wherein phosphate additives are used in preparing polyester resin to improve the reactive property of the esterification reaction or transesterification, as well as the flame retardancy property and the color stability of a polyester resin. The method for preparing a polyester resin comprises the steps of: carrying out an esterification reaction and/or an ester exchange reaction of a diacid component and a diol component in a presence of phosphoric acid derivatives, wherein the diol component comprises a primary diol and isosorbide, and wherein a reaction time of the esterification reaction or the ester exchange reaction is reduced and the remaining rate of isosorbide in the main chain of the polyester resin is increased.

Abstract: A fiber reinforced plastic bolt (FRP) and a method for producing the same are disclosed. The FRP bolt is useful in the industrial areas which require a bolt having electric-insulation, anti-corrosive, thermal-insulation, and non-magnetic properties. The method for producing the FRP bolt includes the steps of: winding a prepreg around a surface of an internal body, wherein the internal body includes a first reinforcing fiber which is unidirectionally aligned along the axis of the bolt, and a synthetic resin which is impregnated into the first reinforcing fiber, and the prepreg includes a second reinforcing fiber and a thermosetting resin which is impregnated into the second reinforcing fiber; forming a fiber reinforced plastic round bar by heat-hardening the prepreg; and forming a screw thread on the surface of the fiber reinforced plastic round bar.

Abstract: The present invention provides a polyester resin including: moieties of dicarboxylic acid components including terephthalic acid; and moieties of diol components including isosorbide, a cyclohexanedimethanol, and the balance of other diol compounds. The polyester resin contains a zinc-based catalyst and a phosphorus-based stabilizer. The present invention also provides a method for preparing the polyester resin. The method includes: esterifying diol components including isosorbide, a cyclohexanedimethanol, and the balance of other diol compounds, with dicarboxylic acid components including terephthalic acid in the presence of an esterification reaction catalyst including a zinc compound; adding a phosphorus-based stabilizer to the esterification reaction mixture at the time when the degree of esterification reaches at least 80%; and subjecting the esterification reaction product to polycondensation.