Abstract: Methods of employing bone defect filling, e.g., orthopedic cements, such as calcium phosphate cements and the like, are provided. A feature of the subject methods is that vibration is employed in conjunction with the use of the cement, e.g., in preparation of the cement, in preparation of the target site, in delivery of the cement to the target site, and/or following delivery of the cement to the target site. Also provided are devices, systems and kits that find use in practicing the subject methods. The subject methods, devices and systems find use in a variety of different applications.

Abstract: Methods are provided for producing porous ?-Tricalcium Phosphate (?-TCP). In the subject methods, ?-TCP is combined with graphite to produce an intermediate greenware product. The intermediate greenware product is then sintered to produce porous ?-TCP. The subject methods and compositions produced thereby find use in a variety of applications.