Abstract: Disclosed herein are skin analysis methods and assays which objectively identify biological strengths and weaknesses in a patient's genetic coding that affect the health and beauty of their skin. Generated results can be utilized to develop personalized skin care and nutritional regimens to prevent, reduce and treat skin deterioration, disorders and diseases. In some embodiments, a method of characterizing a subject's skin is provided which includes generating a personalized skin profile by determining a subject's genetic potential in at least one area of skin health by analyzing one or more skin health-associated single nucleotide polymorphisms or other genetic marker associated with the particular area of skin health being assessed in a sample obtained from the subject. The generated skin profile reveals the subject's genetic strengths, weaknesses and/or risks related to the one or more areas of skin health allowing a personalized skincare and/or nutritional regimen to be developed and implemented.