Abstract: An automated system for signaling cell growth events using continuous sensor data includes at least one sensor associated with a vessel configured for use in growth of cells, the sensor providing continuous sensor data associated with cell growth, a reader in operative communication with the sensor to collect the continuous sensor data, and a computational unit operatively connected to the reader, wherein the computational unit is configured to receive as input the continuous sensor data and calibration data associated with process conditions, the computational unit further configured to perform signal processing on the continuous sensor data in order to predict at least one of future critical events and generate insights about unexpected behavior.
Type:
Application
Filed:
September 26, 2025
Publication date:
April 30, 2026
Applicant:
Skroot Laboratory, Inc.
Inventors:
Nigel F. Reuel, Subhanwit Roy, Aidan Shervheim, Samuel Rothstein, Cameron Greenwalt
Abstract: An apparatus for monitoring cell cultures includes a resonant sensor having a cell transduction membrane for contact with cell culture media, a biocompatible sheet overlaid by the cell transduction membrane, a resonant sheet defining a coil pattern, the resonant sheet overlayed by the biocompatible sheet, a plurality of channels formed in the biocompatible sheet, the plurality channels of having a kerf. The kerf for the plurality of channels is selected such that the resonant sensor is configured to capture exponential phase of cell growth including late exponential cell growth and further capture stationary phases of cell growth for the cell cultures.
Type:
Application
Filed:
September 26, 2025
Publication date:
April 2, 2026
Applicant:
Skroot Laboratory, Inc.
Inventors:
Nigel F. Reuel, Samuel Rothstein, Subhanwit Roy, Aidan Shervheim
Abstract: A system is provided for monitoring foam levels within a vessel wherein one or more chemical reactions or biological growths are occurring. The system includes a resonant sensor positioned outside of the vessel at a position to measure foam level within the vessel, the resonant sensor having an inductive element and a capacitive element and tuned to provide for enhanced sensitivity of changes in local permittivity to resonate.
Type:
Application
Filed:
March 5, 2021
Publication date:
September 8, 2022
Applicant:
Skroot Laboratory, Inc.
Inventors:
Nigel F. Reuel, Cameron Greenwalt, Samuel Rothstein, Charu Gupta
Abstract: A system for reading at least one wireless resonant sensor includes a signal parameter measuring device, a reader housing, a computing device electrically connected to the signal parameter measuring device, and a plurality of reader antennas disposed within the reader housing and electrically connected to the signal parameter measuring device, wherein the plurality of reader antennas comprises a first reader antenna for signal output and a second reader antenna for signal input. The signal parameter measuring device is configured to sweep frequencies over a range of frequencies to acquire signal parameters for the wireless resonant sensor. The computing device is configured to determine changes in resonant frequency of the wireless resonator sensor based on the signal parameters. The reader housing may be sized and shaped for placement against a surface of a vessel in which a chemical or biological process is occurring.
Type:
Application
Filed:
May 17, 2021
Publication date:
November 25, 2021
Applicant:
Skroot Laboratory, Inc.
Inventors:
Nigel F. Reuel, Kyle Jackson, Charu Gupta, Cameron Greenwalt