Abstract: A process to facilitate the fulfillment of drug samples to prescribers in several different manners. A sales representative can request actual drug samples on-line or can order on-line coupons for drug samples to be shipped to a prescriber and from which the prescriber distributes to his patient.

Abstract: An information supply and update system includes abase subsystem and one or more remote user devices. The remote user devices are conveniently handheld devices such as personal digital assitants, cellular telephones, smart phones, paging devices and the like that can receive, store and process information that they receive from the base subsystem. The base subsystem is configured to receive structured information directed to one or more topics, each topic including one or more sections, compress the information topic by typic, and provide the compressed topic information to the remote user devices. The remote user devices are configured receive and store the compressed topic information from the base subsystem. A user's remote user device is further configured to, in response to a request from a user identifying a particular section, enable the information from the section to be displayed on a display.