Abstract: A method for designing one part of an electrostatic separating device of a mixture of different material granules, the method including providing a sorting performance value to be met by the device when at least one predefined mixture is introduced into the device to be sorted, optimizing a value of at least one parameter of the set of parameters relating to the device part by using an optimization technique, the optimization technique including the use of a sorting performance model of the device, and the optimization technique occurring under the constraint that the sorting performed by the device has the given sorting performance value.

Abstract: A device for triboelectric charging of a mixture of granules of different materials, the device having a charging chamber with walls delimiting an inner space. The walls define a granule inlet and a granule outlet, the granule inlet and the granule outlet being separated from one another relative to an elevation direction. A blowing device is arranged suitable for generating, in the inner space, an air flow suitable for allowing the granules in the chamber to form a fluidized bed, and a plurality of grids are positioned in the chamber, the grids being suitable for blocking the passage of the granules, the grids forming a set of baffles in the inner space between the granule inlet and the granule outlet.

Abstract: A method for designing one part of an electrostatic separating device of a mixture of different material granules, the method including providing a sorting performance value to be met by the device when at least one predefined mixture is introduced into the device to be sorted, optimizing a value of at least one parameter of the set of parameters relating to the device part by using an optimization technique, the optimization technique including the use of a sorting performance model of the device, and the optimization technique occurring under the constraint that the sorting performed by the device has the given sorting performance value.

Abstract: An electrostatic separation device (is for a mixture of granules of different materials. The device includes a separation chamber having an inlet and delimiting an inner volume and a collection device for granules placed in the inner volume, opposite the inlet. At least two pairs of electrodes are successively placed in the elevation direction in the inner volume, between the inlet and the collection device. Each pair includes an anode and a cathode, placed on either side of a central axis extending in the elevation direction. At least one generating system is suitable for applying a difference in electric potential between the anode and the cathode of each pair.

Abstract: A device for triboelectric charging of a mixture of granules of different materials, the device having a charging chamber with walls delimiting an inner space. The walls define a granule inlet and a granule outlet, the granule inlet and the granule outlet being separated from one another relative to an elevation direction. A blowing device is arranged suitable for generating, in the inner space, an air flow suitable for allowing the granules in the chamber to form a fluidized bed, and a plurality of grids are positioned in the chamber, the grids being suitable for blocking the passage of the granules, the grids forming a set of baffles in the inner space between the granule inlet and the granule outlet.

Abstract: A mechanical valve assembly for the control of a gas flow to a gas appliance. The mechanical valve assembly includes at least one input knob movably connected to a housing, a shaft assembly connected to at least one input knob, and a manually-operated valve located inside the housing and in between the inlet port and the outlet port. The manually-operated valve is mechanically connected to the shaft assembly, and the manually-operated valve is configured for opening and closing a gas flow between the inlet port and the outlet port.

Abstract: A mechanical valve assembly for the control of a gas flow to a gas appliance, the mechanical valve assembly comprising: a housing; a gas inlet port associated with the housing; a gas outlet port associated with the housing; a timer-controlled valve operable to open and close a gas flow between the inlet port and outlet port; and a manually-operated emergency shut-off valve positioned between the inlet port and the outlet port, ahead of the timer-controlled valve relative to a direction of the gas flow through the mechanical valve assembly.

Abstract: A mechanical valve assembly for the control of a gas flow to a gas appliance, the mechanical valve assembly comprising: a housing; a gas inlet port associated with the housing; a gas outlet port associated with the housing; a timer-controlled valve operable to open and close a gas flow between the inlet port and outlet port; and a manually-operated emergency shut-off valve positioned between the inlet port and the outlet port, ahead of the timer-controlled valve relative to a direction of the gas flow through the mechanical valve assembly.

Abstract: The present invention provides a method and device for reduction of or treatment of deep vein thrombosis (DVT), the method comprising causing isometric stimulation of the leg muscles to promote blood flow. Other embodiments provide treatment for other circulatory disorders of the lower limbs and/or the systemic circulation.

Abstract: Framework (FR)-patching is a novel approach to modify immunoglobulin for reducing potential immunogenicity without significant alterations in specificity and affinity. Unlike previous described methods of humanization, which graft CDRs from a donor onto the frameworks of a single acceptor immunoglobulin, we patch segments of framework (FR1, FR2, FR3, and FR4), or FRs, to replace the corresponding FRs of the parent immunoglobulin. Free assortment of these FRs from different immunoglobulins and from different species can be mixed and matched into forming the final immunoglobulin chain. A set of criteria in the choice of these FRs to minimize or eliminate the need to reintroduce framework amino acids from the parent immunoglobulin for patching is described. The approach gives greater flexibility in the choice of framework sequences, minimizes the need to include parent framework amino acids, and, most importantly, reduces the chances of creating new T- and B-cell epitopes in the resultant immunoglobulin.

Abstract: Framework (FR)-patching is a novel approach to modify immunoglobulin for reducing potential immunogenicity without significant alterations in specificity and affinity. Unlike previous described methods of humanization, which graft CDRs from a donor onto the frameworks of a single acceptor immunoglobulin, we patch segments of framework (FR1, FR2, FR3, and FR4), or FRs, to replace the corresponding FRs of the parent immunoglobulin. Free assortment of these FRs from different immunoglobulins and from different species can be mixed and matched into forming the final immunoglobulin chain. A set of criteria in the choice of these FRs to minimize or eliminate the need to reintroduce framework amino acids from the parent immunoglobulin for patching is described. The approach gives greater flexibility in the choice of framework sequences, minimizes the need to include parent framework amino acids, and, most importantly, reduces the chances of creating new T- and B-cell epitopes in the resultant immunoglobulin.

Abstract: Framework (FR)-patching is a novel approach to modify immunoglobulin for reducing potential immunogenicity without significant alterations in specificity and affinity. Unlike previous described methods of humanization, which graft CDRs from a donor onto the frameworks of a single acceptor immunoglobulin, we patch segments of framework (FR1, FR2, FR3, and FR4), or FRs, to replace the corresponding FRs of the parent immunoglobulin. Free assortment of these FRs from different immunoglobulins and from different species can be mixed and matched into forming the final immunoglobulin chain. A set of criteria in the choice of these FRs to minimize or eliminate the need to reintroduce framework amino acids from the parent immunoglobulin for patching is described. The approach gives greater flexibility in the choice of framework sequences, minimizes the need to include parent framework amino acids, and, most importantly, reduces the chances of creating new T- and B-cell epitopes in the resultant immunoglobulin.

Abstract: Framework (FR)-patching is a novel approach to modify immunoglobulin for reducing potential immunogenicity without significant alterations in specificity and affinity. Unlike previous described methods of humanization, which graft CDRs from a donor onto the frameworks of a single acceptor immunoglobulin, we patch segments of framework (FR1, FR2, FR3, and FR4), or FRs, to replace the corresponding FRs of the parent immunoglobulin. Free assortment of these FRs from different immunoglobulins and from different species can be mixed and matched into forming the final immunoglobulin chain. A set of criteria in the choice of these FRs to minimize or eliminate the need to reintroduce framework amino acids from the parent immunoglobulin for patching is described. The approach gives greater flexibility in the choice of framework sequences, minimizes the need to include parent framework amino acids, and, most importantly, reduces the chances of creating new T- and B-cell epitopes in the resultant immunoglobulin.

Abstract: A modular system (10) for attaching planar panels (12) to a curved support structure (14). The system includes modules (20) that are defined between a transverse hook support panel (36) and a transverse plate support panel (38) and between a base member (78) and a pivot member (80). Each module (20) defines one or more cells (18) in accordance with the use of transverse cross-support members (30). Each panel (12) is secured on a respective cell (18).