Abstract: 3-tert.Butyl-5-nitro-N-pyrid-2'-yl salicylamides which have antiparasitic activity, compositions thereof and methods of controlling parasites in animals infected therewith.
Abstract: The compounds are pyridyl substituted aminoalkylthioureas and ureas which are inhibitors of H-2 histamine receptors. A compound of this invention is N-methyl-N'-[2-(2-pyridylmethylamino)ethyl]thiourea.
Type:
Grant
Filed:
March 13, 1974
Date of Patent:
January 13, 1976
Assignee:
Smith Kline & French Laboratories, Inc.
Inventors:
Graham John Durant, John Colin Emmett, Charon Robin Ganellin
Abstract: Heterocyclic compounds which are inhibitors of histamine activity, in particular, inhibitors of H-2 histamine receptors. A specific compound of this invention is 2-[2-(4-methyl-5-imidazolylmethylthio)ethylamino]-4-pyrimidone.
Type:
Grant
Filed:
April 24, 1974
Date of Patent:
January 13, 1976
Assignee:
Smith Kline & French Laboratories, Inc.
Inventors:
Graham John Durant, John Colin Emmett, Charon Robin Ganellin
Abstract: The compounds are sulphoxides of heterocyclicthioalkylthioureas, ureas and guanidines which are useful to produce inhibition of histamine H-2 receptors.