Patents Assigned to Smith Laboratories, Inc.
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Publication number: 20170119808Abstract: An extended-release topiramate capsule that includes a capsule shell containing a single population of coated particles; wherein each coated particle includes a core and a coating thereon; wherein each particle core includes a homogeneous mixture comprising topiramate throughout its core; and wherein the coating includes one or more release controlling agent(s).Type: ApplicationFiled: November 21, 2016Publication date: May 4, 2017Applicant: Upsher-Smith Laboratories, Inc.Inventors: Sarah Michelle BETTERMAN, Jaidev Srinivas TANTRY, Laura Marie PATRICK
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Patent number: 9555005Abstract: An extended-release topiramate capsule that includes a capsule shell containing a single population of coated particles; wherein each coated particle includes a core and a coating thereon; wherein each particle core includes a homogeneous mixture comprising topiramate throughout its core; and wherein the coating includes one or more release controlling agent(s).Type: GrantFiled: June 5, 2015Date of Patent: January 31, 2017Assignee: Upsher-Smith Laboratories, Inc.Inventors: Sarah Michelle Betterman, Jaidev Srinivas Tantry, Laura Marie Patrick
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Publication number: 20160310508Abstract: Described are gel compositions containing active pharmaceutical ingredient such as testosterone, solvent, and thickener, the gel compositions being useful for transdermal administration of the active ingredient to a patient, and related methods. Certain embodiments of the gel composition specifically exclude Hsieh enhancer.Type: ApplicationFiled: March 25, 2016Publication date: October 27, 2016Applicant: Upsher-Smith Laboratories, Inc.Inventor: Harish K. Pimplaskar
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Patent number: 9456970Abstract: Dermatological compositions (methods of making and using) that include one or more anesthetic agents and/or one or more anti-inflammatory agents and/or a combination of ammonium, sodium, and potassium salts, preferably of an alpha-hydroxy acid.Type: GrantFiled: September 11, 2015Date of Patent: October 4, 2016Assignee: Upsher-Smith Laboratories, Inc.Inventors: Gloria A. Rood, Kenneth L. Evenstad, Victoria A. O'Neill
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Patent number: 9295675Abstract: Described are gel compositions containing active pharmaceutical ingredient such as testosterone, solvent, and thickener, the gel compositions being useful for transdermal administration of the active ingredient to a patient, and related methods. Certain embodiments of the gel composition specifically exclude Hsieh enhancer.Type: GrantFiled: June 17, 2014Date of Patent: March 29, 2016Assignee: Upsher-Smith Laboratories, Inc.Inventor: Harish K. Pimplaskar
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Publication number: 20160051475Abstract: The present invention provides sustained-release oral pharmaceutical compositions and methods of use. The sustained-release oral pharmaceutical compositions include an amine-containing compound (e.g., an opioid) (including salts thereof) and a pharmaceutically acceptable salt of a non-NSAID cyclic organic acid compound.Type: ApplicationFiled: September 11, 2015Publication date: February 25, 2016Applicant: Upsher-Smith Laboratories, Inc.Inventors: Ronnie Ortiz, James S. Jensen, Kristopher R. Lundell, Victoria Ann O'Neill, Sean Mahoney
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Patent number: 9023390Abstract: Sustained-release oral pharmaceutical compositions and methods of use, wherein the compositions are in a single dosage form and include an amine-containing compound (including salts thereof), a salt of a non-steroidal anti-inflammatory drug (NSAID), and a hydrophilic matrix.Type: GrantFiled: December 31, 2009Date of Patent: May 5, 2015Assignee: Upsher-Smith Laboratories, Inc.Inventors: Christian F. Wertz, James S. Jensen, Victoria Ann O'Neill, Sean B. Mahoney, Stephen M. Berge
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Patent number: 8987291Abstract: The present invention provides sustained-release oral pharmaceutical compositions and methods of use. The sustained-release oral pharmaceutical compositions include an opioid (including salts thereof) and a salt of a non-steroidal anti-inflammatory drug (NSAID).Type: GrantFiled: December 14, 2012Date of Patent: March 24, 2015Assignee: Upsher Smith Laboratories, Inc.Inventors: Kenneth L. Evenstad, Christian F. Wertz, James S. Jensen, Victoria Ann O'Neill, Stephen M. Berge
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Patent number: 8889190Abstract: An extended-release topiramate capsule that includes a capsule shell containing a single population of coated particles; wherein each coated particle includes a core and a coating thereon; wherein each particle core includes a homogeneous mixture comprising topiramate throughout its core; and wherein the coating includes one or more release controlling agent(s).Type: GrantFiled: January 17, 2014Date of Patent: November 18, 2014Assignee: Upsher-Smith Laboratories, Inc.Inventors: Sarah Michelle Betterman, Jaidev Srinivas Tantry, Laura Marie Patrick
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Publication number: 20140271839Abstract: An extended-release topiramate capsule that includes a capsule shell containing a single population of coated particles; wherein each coated particle includes a core and a coating thereon; wherein each particle core includes a homogeneous mixture comprising topiramate throughout its core; and wherein the coating includes one or more release controlling agent(s).Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: Upsher-Smith Laboratories, Inc.Inventors: Sarah Michelle Betterman, Jaidev Srinivas Tantry, Laura Marie Patrick
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Patent number: 8785426Abstract: Described are gel compositions containing active pharmaceutical ingredient such as testosterone, solvent, and thickener, the gel compositions being useful for transdermal administration of the active ingredient to a patient, and related methods. Certain embodiments of the gel composition specifically exclude Hsieh enhancer.Type: GrantFiled: February 11, 2014Date of Patent: July 22, 2014Assignee: Upsher-Smith Laboratories, Inc.Inventor: Harish K. Pimplaskar
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Patent number: 8652527Abstract: An extended-release topiramate capsule that includes a capsule shell containing a single population of coated particles; wherein each coated particle includes a core and a coating thereon; wherein each particle core includes a homogeneous mixture comprising topiramate throughout its core; and wherein the coating includes one or more release controlling agent(s).Type: GrantFiled: March 19, 2013Date of Patent: February 18, 2014Assignee: Upsher-Smith Laboratories, IncInventors: Sarah Michelle Betterman, Jaidev Srinvas Tantry, Laura Marie Patrick
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Patent number: 8362029Abstract: The present invention provides sustained-release oral pharmaceutical compositions and methods of use. The sustained-release oral pharmaceutical compositions include an opioid (including salts thereof) and a salt of a non-steroidal anti-inflammatory drug (NSAID).Type: GrantFiled: December 31, 2009Date of Patent: January 29, 2013Assignee: Upsher-Smith Laboratories, Inc.Inventors: Kenneth L. Evenstad, Christian F. Wertz, James S. Jensen, Victoria Ann O'Neill, Stephen M. Berge
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Patent number: 8013017Abstract: Dermatological compositions (methods of making and using) that include one or more anesthetic agents and/or one or more anti-inflammatory agents and/or a combination of ammonium, sodium, and potassium salts, preferably of an alpha-hydroxy acid.Type: GrantFiled: June 5, 2009Date of Patent: September 6, 2011Assignee: Upsher-Smith Laboratories, Inc.Inventors: Gloria A. Rood, Kenneth L. Evenstad, Victoria A. O'Neill
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Patent number: 7056534Abstract: This invention provides extended release potassium chloride granules consisting essentially of potassium chloride crystals having a mesh size of about 20–60 mesh that are coated only with ethylcellulose. The granules may be compressed into tablets that disintegrate rapidly in an aqueous environment to provide uniform dissolution of the potassium chloride. Tablets containing about 10 to about 20 milliequivalents potassium may be formulated in accordance with the invention. Processes to produce extended release granules without using surfactants, processing aids or other coating aids are also provided by this invention. A method is further provided whereby a patient's supplemental potassium requirements are met by administering an appropriate combination of dosage units chosen from available dosage units containing different quantities of potassium.Type: GrantFiled: August 19, 2004Date of Patent: June 6, 2006Assignee: Upsher-Smith Laboratories, Inc.Inventors: Bradley L. Christenson, Phillip W. Dritsas
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Patent number: 6977081Abstract: The present invention provides emollient creams composed of sulfur, sodium sulfacetamide and a botanically-derived anti-inflammatory ingredient. The creams are alcohol-free and have a pH at or above 7.0.Type: GrantFiled: December 18, 2002Date of Patent: December 20, 2005Assignee: Upsher-Smith Laboratories, Inc.Inventor: Gloria Rood
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Publication number: 20050079219Abstract: This invention provides extended release potassium chloride granules consisting essentially of potassium chloride crystals having a mesh size of about 20-60 mesh that are coated only with ethylcellulose. The granules may be compressed into tablets that disintegrate rapidly in an aqueous environment to provide uniform dissolution of the potassium chloride. Tablets containing about 10 to about 20 milliequivalents potassium may be formulated in accordance with the invention. Processes to produce extended release granules without using surfactants, processing aids or other coating aids are also provided by this invention. A method is further provided whereby a patient's supplemental potassium requirements are met by administering an appropriate combination of dosage units chosen from available dosage units containing different quantities of potassium.Type: ApplicationFiled: August 19, 2004Publication date: April 14, 2005Applicant: Upsher-Smith Laboratories, Inc.Inventors: Bradley Christenson, Phillip Dritsas
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Patent number: 6780437Abstract: This invention provides extended release potassium chloride granules consisting essentially of potassium chloride crystals having a mesh size of about 20-60 mesh that are coated only with ethylcellulose. The granules may be compressed into tablets that disintegrate rapidly in an aqueous environment to provide uniform dissolution of the potassium chloride. Tablets containing about 10 to about 20 milliequivalents potassium may be formulated in accordance with the invention. Processes to produce extended release granules without using surfactants, processing aids or other coating aids are also provided by this invention. A method is further provided whereby a patient's supplemental potassium requirements are met by administering an appropriate combination of dosage units chosen from available dosage units containing different quantities of potassium.Type: GrantFiled: February 14, 2002Date of Patent: August 24, 2004Assignee: Upsher-Smith Laboratories, Inc.Inventors: Bradley L. Christenson, Mark J. Pieloch
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Patent number: 6769232Abstract: Apparatus and method for retaining cotton in a bottle using a cottoner machine which inserts cotton via a pair of rotatable cylinders alignable with a mouth of the bottle, the apparatus including a disk secured to the cylinders via a pair of collars and having a pair of apertures aligned with the cylinders, and the method including a process of positioning a planar surface of the disk closely superjacent the mouth of the bottle after insertion of the cotton.Type: GrantFiled: June 11, 2003Date of Patent: August 3, 2004Assignee: Upsher-Smith Laboratories, Inc.Inventor: Mark A. Haida
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Publication number: 20030205031Abstract: Apparatus and method for retaining cotton in a bottle using a cottoner machine which inserts cotton via a pair of rotatable cylinders alignable with a mouth of the bottle, the apparatus including a disk secured to the cylinders via a pair of collars and having a pair of apertures aligned with the cylinders, and the method including a process of positioning a planar surface of the disk closely superjacent the mouth of the bottle after insertion of the cotton.Type: ApplicationFiled: June 11, 2003Publication date: November 6, 2003Applicant: Upsher-Smith Laboratories, Inc.Inventor: Mark A. Haida