Patents Assigned to Smith Laboratories, Inc.
  • Publication number: 20170119808
    Abstract: An extended-release topiramate capsule that includes a capsule shell containing a single population of coated particles; wherein each coated particle includes a core and a coating thereon; wherein each particle core includes a homogeneous mixture comprising topiramate throughout its core; and wherein the coating includes one or more release controlling agent(s).
    Type: Application
    Filed: November 21, 2016
    Publication date: May 4, 2017
    Applicant: Upsher-Smith Laboratories, Inc.
    Inventors: Sarah Michelle BETTERMAN, Jaidev Srinivas TANTRY, Laura Marie PATRICK
  • Patent number: 9555005
    Abstract: An extended-release topiramate capsule that includes a capsule shell containing a single population of coated particles; wherein each coated particle includes a core and a coating thereon; wherein each particle core includes a homogeneous mixture comprising topiramate throughout its core; and wherein the coating includes one or more release controlling agent(s).
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: January 31, 2017
    Assignee: Upsher-Smith Laboratories, Inc.
    Inventors: Sarah Michelle Betterman, Jaidev Srinivas Tantry, Laura Marie Patrick
  • Publication number: 20160310508
    Abstract: Described are gel compositions containing active pharmaceutical ingredient such as testosterone, solvent, and thickener, the gel compositions being useful for transdermal administration of the active ingredient to a patient, and related methods. Certain embodiments of the gel composition specifically exclude Hsieh enhancer.
    Type: Application
    Filed: March 25, 2016
    Publication date: October 27, 2016
    Applicant: Upsher-Smith Laboratories, Inc.
    Inventor: Harish K. Pimplaskar
  • Patent number: 9456970
    Abstract: Dermatological compositions (methods of making and using) that include one or more anesthetic agents and/or one or more anti-inflammatory agents and/or a combination of ammonium, sodium, and potassium salts, preferably of an alpha-hydroxy acid.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: October 4, 2016
    Assignee: Upsher-Smith Laboratories, Inc.
    Inventors: Gloria A. Rood, Kenneth L. Evenstad, Victoria A. O'Neill
  • Patent number: 9295675
    Abstract: Described are gel compositions containing active pharmaceutical ingredient such as testosterone, solvent, and thickener, the gel compositions being useful for transdermal administration of the active ingredient to a patient, and related methods. Certain embodiments of the gel composition specifically exclude Hsieh enhancer.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: March 29, 2016
    Assignee: Upsher-Smith Laboratories, Inc.
    Inventor: Harish K. Pimplaskar
  • Publication number: 20160051475
    Abstract: The present invention provides sustained-release oral pharmaceutical compositions and methods of use. The sustained-release oral pharmaceutical compositions include an amine-containing compound (e.g., an opioid) (including salts thereof) and a pharmaceutically acceptable salt of a non-NSAID cyclic organic acid compound.
    Type: Application
    Filed: September 11, 2015
    Publication date: February 25, 2016
    Applicant: Upsher-Smith Laboratories, Inc.
    Inventors: Ronnie Ortiz, James S. Jensen, Kristopher R. Lundell, Victoria Ann O'Neill, Sean Mahoney
  • Patent number: 9023390
    Abstract: Sustained-release oral pharmaceutical compositions and methods of use, wherein the compositions are in a single dosage form and include an amine-containing compound (including salts thereof), a salt of a non-steroidal anti-inflammatory drug (NSAID), and a hydrophilic matrix.
    Type: Grant
    Filed: December 31, 2009
    Date of Patent: May 5, 2015
    Assignee: Upsher-Smith Laboratories, Inc.
    Inventors: Christian F. Wertz, James S. Jensen, Victoria Ann O'Neill, Sean B. Mahoney, Stephen M. Berge
  • Patent number: 8987291
    Abstract: The present invention provides sustained-release oral pharmaceutical compositions and methods of use. The sustained-release oral pharmaceutical compositions include an opioid (including salts thereof) and a salt of a non-steroidal anti-inflammatory drug (NSAID).
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: March 24, 2015
    Assignee: Upsher Smith Laboratories, Inc.
    Inventors: Kenneth L. Evenstad, Christian F. Wertz, James S. Jensen, Victoria Ann O'Neill, Stephen M. Berge
  • Patent number: 8889190
    Abstract: An extended-release topiramate capsule that includes a capsule shell containing a single population of coated particles; wherein each coated particle includes a core and a coating thereon; wherein each particle core includes a homogeneous mixture comprising topiramate throughout its core; and wherein the coating includes one or more release controlling agent(s).
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: November 18, 2014
    Assignee: Upsher-Smith Laboratories, Inc.
    Inventors: Sarah Michelle Betterman, Jaidev Srinivas Tantry, Laura Marie Patrick
  • Publication number: 20140271839
    Abstract: An extended-release topiramate capsule that includes a capsule shell containing a single population of coated particles; wherein each coated particle includes a core and a coating thereon; wherein each particle core includes a homogeneous mixture comprising topiramate throughout its core; and wherein the coating includes one or more release controlling agent(s).
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: Upsher-Smith Laboratories, Inc.
    Inventors: Sarah Michelle Betterman, Jaidev Srinivas Tantry, Laura Marie Patrick
  • Patent number: 8785426
    Abstract: Described are gel compositions containing active pharmaceutical ingredient such as testosterone, solvent, and thickener, the gel compositions being useful for transdermal administration of the active ingredient to a patient, and related methods. Certain embodiments of the gel composition specifically exclude Hsieh enhancer.
    Type: Grant
    Filed: February 11, 2014
    Date of Patent: July 22, 2014
    Assignee: Upsher-Smith Laboratories, Inc.
    Inventor: Harish K. Pimplaskar
  • Patent number: 8652527
    Abstract: An extended-release topiramate capsule that includes a capsule shell containing a single population of coated particles; wherein each coated particle includes a core and a coating thereon; wherein each particle core includes a homogeneous mixture comprising topiramate throughout its core; and wherein the coating includes one or more release controlling agent(s).
    Type: Grant
    Filed: March 19, 2013
    Date of Patent: February 18, 2014
    Assignee: Upsher-Smith Laboratories, Inc
    Inventors: Sarah Michelle Betterman, Jaidev Srinvas Tantry, Laura Marie Patrick
  • Patent number: 8362029
    Abstract: The present invention provides sustained-release oral pharmaceutical compositions and methods of use. The sustained-release oral pharmaceutical compositions include an opioid (including salts thereof) and a salt of a non-steroidal anti-inflammatory drug (NSAID).
    Type: Grant
    Filed: December 31, 2009
    Date of Patent: January 29, 2013
    Assignee: Upsher-Smith Laboratories, Inc.
    Inventors: Kenneth L. Evenstad, Christian F. Wertz, James S. Jensen, Victoria Ann O'Neill, Stephen M. Berge
  • Patent number: 8013017
    Abstract: Dermatological compositions (methods of making and using) that include one or more anesthetic agents and/or one or more anti-inflammatory agents and/or a combination of ammonium, sodium, and potassium salts, preferably of an alpha-hydroxy acid.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: September 6, 2011
    Assignee: Upsher-Smith Laboratories, Inc.
    Inventors: Gloria A. Rood, Kenneth L. Evenstad, Victoria A. O'Neill
  • Patent number: 7056534
    Abstract: This invention provides extended release potassium chloride granules consisting essentially of potassium chloride crystals having a mesh size of about 20–60 mesh that are coated only with ethylcellulose. The granules may be compressed into tablets that disintegrate rapidly in an aqueous environment to provide uniform dissolution of the potassium chloride. Tablets containing about 10 to about 20 milliequivalents potassium may be formulated in accordance with the invention. Processes to produce extended release granules without using surfactants, processing aids or other coating aids are also provided by this invention. A method is further provided whereby a patient's supplemental potassium requirements are met by administering an appropriate combination of dosage units chosen from available dosage units containing different quantities of potassium.
    Type: Grant
    Filed: August 19, 2004
    Date of Patent: June 6, 2006
    Assignee: Upsher-Smith Laboratories, Inc.
    Inventors: Bradley L. Christenson, Phillip W. Dritsas
  • Patent number: 6977081
    Abstract: The present invention provides emollient creams composed of sulfur, sodium sulfacetamide and a botanically-derived anti-inflammatory ingredient. The creams are alcohol-free and have a pH at or above 7.0.
    Type: Grant
    Filed: December 18, 2002
    Date of Patent: December 20, 2005
    Assignee: Upsher-Smith Laboratories, Inc.
    Inventor: Gloria Rood
  • Publication number: 20050079219
    Abstract: This invention provides extended release potassium chloride granules consisting essentially of potassium chloride crystals having a mesh size of about 20-60 mesh that are coated only with ethylcellulose. The granules may be compressed into tablets that disintegrate rapidly in an aqueous environment to provide uniform dissolution of the potassium chloride. Tablets containing about 10 to about 20 milliequivalents potassium may be formulated in accordance with the invention. Processes to produce extended release granules without using surfactants, processing aids or other coating aids are also provided by this invention. A method is further provided whereby a patient's supplemental potassium requirements are met by administering an appropriate combination of dosage units chosen from available dosage units containing different quantities of potassium.
    Type: Application
    Filed: August 19, 2004
    Publication date: April 14, 2005
    Applicant: Upsher-Smith Laboratories, Inc.
    Inventors: Bradley Christenson, Phillip Dritsas
  • Patent number: 6780437
    Abstract: This invention provides extended release potassium chloride granules consisting essentially of potassium chloride crystals having a mesh size of about 20-60 mesh that are coated only with ethylcellulose. The granules may be compressed into tablets that disintegrate rapidly in an aqueous environment to provide uniform dissolution of the potassium chloride. Tablets containing about 10 to about 20 milliequivalents potassium may be formulated in accordance with the invention. Processes to produce extended release granules without using surfactants, processing aids or other coating aids are also provided by this invention. A method is further provided whereby a patient's supplemental potassium requirements are met by administering an appropriate combination of dosage units chosen from available dosage units containing different quantities of potassium.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: August 24, 2004
    Assignee: Upsher-Smith Laboratories, Inc.
    Inventors: Bradley L. Christenson, Mark J. Pieloch
  • Patent number: 6769232
    Abstract: Apparatus and method for retaining cotton in a bottle using a cottoner machine which inserts cotton via a pair of rotatable cylinders alignable with a mouth of the bottle, the apparatus including a disk secured to the cylinders via a pair of collars and having a pair of apertures aligned with the cylinders, and the method including a process of positioning a planar surface of the disk closely superjacent the mouth of the bottle after insertion of the cotton.
    Type: Grant
    Filed: June 11, 2003
    Date of Patent: August 3, 2004
    Assignee: Upsher-Smith Laboratories, Inc.
    Inventor: Mark A. Haida
  • Publication number: 20030205031
    Abstract: Apparatus and method for retaining cotton in a bottle using a cottoner machine which inserts cotton via a pair of rotatable cylinders alignable with a mouth of the bottle, the apparatus including a disk secured to the cylinders via a pair of collars and having a pair of apertures aligned with the cylinders, and the method including a process of positioning a planar surface of the disk closely superjacent the mouth of the bottle after insertion of the cotton.
    Type: Application
    Filed: June 11, 2003
    Publication date: November 6, 2003
    Applicant: Upsher-Smith Laboratories, Inc.
    Inventor: Mark A. Haida