Abstract: A compound comprising a metal species and a biologically acceptable ligand, wherein the biologically acceptable ligand comprises a biguanide moiety, and wherein the biologically acceptable ligand forms a complex with the metal species in which the metal species is stabilised in an oxidation state greater than 1+. Compositions and medical devices comprising the compound. A method for the treatment or prophylaxis of microbial, including bacterial, infections, comprising the use of such compounds, compositions or medical devices.
Abstract: A method and apparatus are disclosed for delivering at least one agent to a wound site. The method includes the steps of providing a delivery tube having an outlet at a wound site, covering the wound site with a drape and introducing agent at an agent inlet port of the delivery tube. The agent passes along the delivery tube through the drape to the wound site. The agent can be a wide variety or mixture of fluids such as but not limited to pain relief medicament, anti-biotics, saline solution and/or hydrating fluid.
Abstract: The invention generally relates to biodegradable and/or bioresorbable fibrous articles and more particularly to products and methods having utility in medical applications.
Type:
Application
Filed:
March 10, 2017
Publication date:
June 29, 2017
Applicant:
Smith & Nephew PLC
Inventors:
Michael John Raxworthy, Peter Damien Iddon, Jennifer Margaret Smith
Abstract: A polyurethane material for the detection or sensing of species or stimulus comprising a polyurethane network comprising immobilised therein, or modified by the immobilisation therein of, a hydrophilic polymer comprising a ligand or moiety for the detection or sensing of species or stimulus and an indicator for indicating detection or sensing wherein species or stimulus is selected from chemical or biological species or stimulus; the material for medical, dental, hygiene, point of use sterilisation, sanitation, personal care, biosurveillance or packaging use, the use thereof preferably for detecting and/or sensing or binding bacteria, or for detecting or sensing pH or for detection or scanning with use of a reader; a Kit and a device comprising the same; and a process for the preparation thereof
Type:
Application
Filed:
July 3, 2015
Publication date:
June 29, 2017
Applicant:
Smith & Nephew PLC
Inventors:
John Kenneth HICKS, Stephen RIMMER, Dorothy MCCULLOCH, Richard HOSKINS
Abstract: Embodiments disclosed herein are directed to negative pressure treatment systems and wound dressing systems, apparatuses, and methods that may be used for the treatment of wounds. In particular, some embodiments are directed to improved wound dressings comprising an obscuring layer that may hide fluid contained therein. Some embodiments may further comprise one or more viewing windows disposed therethrough so as to enable monitoring or examination of fluids contained therein.
Type:
Grant
Filed:
March 13, 2015
Date of Patent:
May 30, 2017
Assignee:
Smith & Nephew PLC
Inventors:
Sarah Jenny Collinson, Philip Gowans, Mark Russell
Abstract: Apparatus and a method for the provision of topical negative pressure therapy to a wound site are described, the apparatus comprising: vacuum generating means for generating a negative pressure at said wound site said vacuum generating means being operably connected to a dressing at said wound site by aspiration conduit means; pressure sensing conduit means in fluid communication with said aspiration conduit means at a junction adjacent said dressing; first pressure sensing means between said junction and said vacuum generating means; second pressure sensing means operably associated with said pressure sensing conduit means; diagnostic means in communication with said first and second pressure sensing means; and control means in communication with said diagnostic means for controlling pressure in said aspiration and said pressure sensing conduit means.
Abstract: Apparatus (10, 200) for the provision of TNP therapy to a wound is described, the apparatus (10, 200) including: a waste canister (22, 204) into which fluid is aspirated from a wound by aspiration pump means (44, 248) and a fluid flow path (420, 422) for at least a part of said aspirated fluid on an outlet side of said aspiration pump means (44) wherein said fluid flow path (420, 422) on the outlet side comprises a silencing system (400) having a plurality of silencing elements (402, 404, 406) therein.
Abstract: The invention relates to a method and apparatus to continuously monitor and control acoustic energy and vacuum pressure to maintain a net unidirectional flow of multi-phase heterogeneous fluids through a porous filter or membrane. The heterogeneous fluid may come form a variety of sources including biological sources such as, blood, bone marrow aspirate (BMA), adipose tissue (lipoaspirate), urine, saliva, etc.
Type:
Grant
Filed:
March 3, 2015
Date of Patent:
May 2, 2017
Assignee:
Smith & Nephew PLC
Inventors:
Stephen John Curran, Jonathan Nicholas Ridgway, Pei-Sheng Chen, Michael Pratt, Marc Tanner, Stephen Latham, Nick Reback
Abstract: An apparatus for cleansing and promoting tissue growth in wounds, in which irrigant fluid optionally containing cell nutrients and/or other physiologically active material from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing, a biodegradable scaffold in contact with the wound bed and a means for fluid cleansing and back to the dressing. The apparatus has means for supplying thermal energy to the fluid in the wound. The cleansing means (which may be a single-phase, e.g. micro-filtration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The dressing and a method of treatment using the apparatus.
Type:
Grant
Filed:
February 12, 2016
Date of Patent:
April 11, 2017
Assignee:
Smith & Nephew PLC
Inventors:
Patrick Lewis Blott, Bryan Greener, Edward Yerbury Hartwell, Tina Michelle Walker, Julian Lee-Webb, Derek Nicolini, Clare Green, Robin Paul Martin
Abstract: A carrying case (500) and handle (504) for accommodating a portable topical negative pressure therapy apparatus (200) comprising a device (202) and a waste canister (204) separable therefrom, the waste canister having an aspiration conduit (274) emerging therefrom is described, the carrying bag comprising an apparatus receiving pouch (502), said pouch having opening and closing means (522, 524) at a lower portion thereof and said handle (504) being directly attached to said apparatus.
Abstract: An apparatus and method for aspirating, irrigating and/or cleansing wounds is provided. The apparatus and method include one or more of the following: simultaneous aspiration and irrigation of the wound, supplying of thermal energy to fluid circulated through the wound; supplying physiologically active agents to the wound; a biodegradable scaffold in contact with the wound bed; and application of stress or flow stress to the wound bed.
Type:
Grant
Filed:
September 25, 2014
Date of Patent:
January 17, 2017
Assignee:
Smith & Nephew PLC
Inventors:
Patrick Lewis Blott, Edward Yerbury Hartwell, Julian Lee-Webb, Derek Nicolini, Clare Green, Robin Paul Martin
Abstract: An implantable dental device comprising polymeric shape memory material for implantation into a cavity within alveolar bone of the jaw or within the root canal space of a tooth.
Type:
Grant
Filed:
April 15, 2008
Date of Patent:
January 17, 2017
Assignee:
Smith & Nephew plc
Inventors:
Peter Arnold, Daniel Sarefjord, Andrew Thompson
Abstract: An apparatus for cleansing wounds with means for stressing the wound bed and optionally tissue surrounding the wound, in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a devise for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing. The cleansing means (which may be a single-phase, e.g. micro-filtration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The means for stressing the wound bed and optionally tissue surrounding the wound promotes wound healing. The dressing and a method of treatment using the apparatus.
Type:
Grant
Filed:
February 19, 2014
Date of Patent:
December 27, 2016
Assignee:
Smith & Nephew PLC
Inventors:
Patrick Lewis Blott, Bryan Greener, Edward Yerbury Hartwell, Julian Lee-Webb, Derek Nicolini, Clare Green, Robin Paul Martin
Abstract: An apparatus and method for aspirating, irrigating and/or cleansing wounds is provided. The apparatus and method include one or more of the following: simultaneous aspiration and irrigation of the wound, supplying of thermal energy to fluid circulated through the wound; supplying physiologically active agents to the wound; a biodegradable scaffold in contact with the wound bed; and application of stress or flow stress to the wound bed.
Type:
Grant
Filed:
September 25, 2014
Date of Patent:
December 6, 2016
Assignee:
Smith & Nephew PLC
Inventors:
Patrick Lewis Blott, Edward Yerbury Hartwell, Julian Lee-Webb, Derek Nicolini, Clare Green, Robin Paul Martin
Abstract: An apparatus for cleansing wounds, in which wound exudate is removed from a wound bed and selectively cleansed and returned to the wound. The cleansing means removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The associated wound dressing and cleansing means are conformable to the wound, and may have irrigant fluid circulated from a reservoir by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing.
Type:
Grant
Filed:
December 18, 2014
Date of Patent:
September 27, 2016
Assignee:
Smith & Nephew PLC
Inventors:
Patrick Lewis Blott, Bryan Greener, Edward Yerbury Hartwell, Derek Nicolini, Tina Michelle Walker, Julian Lee-Webb
Abstract: An apparatus for cleansing wounds with means for stressing the wound bed and optionally tissue surrounding the wound, in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing. The cleansing means (which may be a single-phase, e.g. micro-filtration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The means for stressing the wound bed and optionally tissue surrounding the wound promotes wound healing. The dressing and a method of treatment using the apparatus.
Type:
Grant
Filed:
July 7, 2010
Date of Patent:
September 27, 2016
Assignee:
SMITH & NEPHEW PLC
Inventors:
Patrick Lewis Blott, Bryan Greener, Edward Yerbury Hartwell, Tina Michelle Walker, Julian Lee-Webb, Derek Nicolini, Clare Green, Robin Paul Martin
Abstract: An apparatus for cleansing wounds, in which wound exudate is removed from a wound bed and selectively cleansed and returned to the wound. The cleansing means removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The associated wound dressing and cleansing means are conformable to the wound, and may have irrigant fluid circulated from a reservoir by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing.
Type:
Grant
Filed:
August 17, 2011
Date of Patent:
September 20, 2016
Assignee:
Smith & Nephew PLC
Inventors:
Patrick Lewis Blott, Bryan Greener, Edward Yerbury Hartwell, Derek Nicolini, Tina Michelle Walker, Julian Lee-Webb