Abstract: The present invention relates to an oil in water emulsion vaccine composition. In particular, the present invention relates to a vaccine adjuvant formulation based on oil in water emulsion comprising a metabolisable oil and a saponin, wherein the oil and a saponin are present in a ratio of between 1:1 and 200:1. The invention further relates to methods for preparing the emulsion and its use in medicine.
Type:
Grant
Filed:
May 6, 2002
Date of Patent:
January 29, 2008
Assignee:
Smithkline Beecham Biologicals SG
Inventors:
Nathalie Garcon, Patricia Marie Christine Aline Francoise Momin