Abstract: Invented are metal chelated dimeric cell-surface receptor ligands, pharmaceutical compositions containing these compounds, and methods of using these compounds as agonist of dimeric cell-surface receptors. Also invented are novel processes used in preparing these compounds. Also invented are novel receptor binding moieties of the invented metal chelated cell-surface receptor ligands.
Type:
Application
Filed:
August 12, 2002
Publication date:
January 16, 2003
Applicant:
SmithKline Beecham Corporation and Ligand Pharmaceuticals
Inventors:
Juan I. Luengo, Stephen G. Miller, John G. Gleason