Abstract: The present invention relates to a salt of carvedilol, corresponding compositions containing such a carvedilol salt or corresponding solvates thereof, and/or methods of using the aforementioned compound(s) in the treatment of certain disease states in mammals, in particular man. The present invention further relates to a novel crystalline form of carvedilol hydrobromide, which is the hydrobromide salt of 1-(carbazol-4-yloxy-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol, and/or other carvedilol solvates thereof, compositions containing salts or solvates of carvedilol hydrobromide, and methods of using the aforementioned compound(s) to treat hypertension, congestive heart failure, and angina, etc.
Type:
Grant
Filed:
October 11, 2006
Date of Patent:
January 19, 2010
Assignee:
SmithKline Beechman Cork Limited
Inventors:
Pingyun Y. Chen, Qunying Dai, Philip C. Dell'Orco, Claire Hisler, David H. Igo, Lee M. Katrincic, Clifford S. Labaw, Li-Jen J. Ping