Patents Assigned to SmithKline Biologicals
  • Process for the extraction and purification of proteins from culture media producing them
    Patent number: 4857317
    Abstract: The process is applicable to the supernatant of engineered yeast cells disrupted in the presence of a non-ionic detergent; it comprises the precipitation of contaminants by polyethylene glycol and the treatment of this latter supernatant with either a bivalent metal cation or, after eventual ultrafiltration, with ammonium sulfate.
    Type: Grant
    Filed: April 27, 1987
    Date of Patent: August 15, 1989
    Assignee: SmithKline Biologicals
    Inventors: Frans V. Wijnendaele, Daniel Gilles, Guy Simonet