Abstract: A secretory component-containing composition which is obtainable by contacting a milk or a whey with a cation exchange resin to allow the resin to absorb a secretory component contained in the milk or the whey and then eluting the secretory component and which has the following properties:(a) contains a secretory component with the purity of at least 20% by weight,(b) contains, besides the secretory component, at least an immunoglobulin and/or a serum albumin, and(c) has anti-infectious effects.