Abstract: In preparation of a salt-containing low-fat spread with no more than 40 wt. % fat content, it is possible to provide a salt-containing low-fat spread which melt well in the mouth and the emulsification of which is swiftly broken, thereby releasing a preferable flavor once placed in the mouth and yet causing no problems in manufacturing, by selecting and combining emulsifiers so that a specific demulsification property with an electric conductivity rise of at least 0.1 mS/cm within 300 seconds at approximately 36.degree. C.
Abstract: Provided are stable hydrate crystals of 14.alpha.-hydroxy-4-androstene-3,6,17-trione having a biological activity of human placenta-originating estrodiene synthesis enzyme inhibitory action. These hydrate crystals include two kinds of 14.alpha.-hydroxy-4-androstene-3,6,17-trione hydrate crystals having a diffraction pattern having characteristic peaks at diffraction angles in crystalline powder X-ray diffraction. Processes for producing these hydrate crystals are also provided.