Abstract: The present invention provides an implantable microneedle and a manufacturing method therefor. An implantable microneedle according to the present invention comprises a coating layer for covering at least one part of the surface of a tip part of the microneedle. When exposed to moisture, the coating layer can be separated from the tip part of the microneedle and thus be implanted.

Abstract: The present invention relates to a photocurable hemostatic composition and, specifically, to a photocurable liquid hemostatic composition containing a hyaluronic acid-based photocrosslinkable compound and a photoinitiator as active ingredients, and to a hemostatic agent of a film or sponge formulation freeze-dried from the composition, wherein, by increasing the degree of substitution of a photocrosslinkable functional group, the composition can quickly form a gel or a film adhesive layer within a few seconds during light radiation, and the resulting gel remains in a body more stably for a long time, thus enhancing hemostasis and tissue regeneration effects.

Abstract: There are provided a photo-cross-linking copolymerized hyaluronic acid sponge and a preparation method therefor, the sponge not being sticky and not dripping, having flexibility to be usable in various parts of the body, having excellent water binding force to help tissue regeneration, having very excellent biocompatibility so as to be absorbable into the skin when attached to the body for a long time, so that the trouble of having to be removed can be decreased, and comprising, through a photo-cross-linking reaction, polymers having various lengths so as to be applicable in various forms of medical antihemorrhagic agents, wound-coating agents, adhesive barriers.

Abstract: The present invention relates to the manufacture of a photo-crosslinkable biodegradable tissue adhesive using a multinetwork-forming copolymer, and provides a hyaluronic acid copolymer compound having excellent elongation, mechanical properties, and tissue adhesion. The compound fundamentally does not undergo phase separation, and enables the manufacture of a tissue adhesive with desired adhesive characteristics and physical characteristics.

Abstract: An implantable substance delivery vehicle of the present invention comprises: a pin comprising a bevel tip and an engraved groove on the surface of the bevel tip; and a substance to be delivered into the body, inserted so as so as to protrude outwardly from the tip, wherein, when the implantable substance delivery vehicle is used for implantation, the substance to be delivered into the body, inserted so as so as to protrude, is caught in tissue so as to be readily detached.

Abstract: A photocrosslinkable hydrogel may comprise a radioisotope-labeled photocrosslinkable compound or a pharmaceutically acceptable salt thereof, which may be used as a composition for radiotherapy, a composition for radiodiagnostic imaging and a composition for anticancer treatment. The hydrogel is excellent in staying in a local area requiring radiation treatment, so that it can be treated while minimizing damage to surrounding tissues. In addition, it can be used in combination with an anticancer agent and used as a pharmaceutical composition for anticancer treatment, so that cancer can be effectively treated. The hydrogel can be manufactured on site immediately and conveniently using a portable microfluidic system, thereby maximizing the radiation treatment effect.

Abstract: Disclosed is an apparatus for manufacturing a microneedle patch, including: a silicon mold mounted on an upper surface to mold a material for the microneedle patch; a carrier of which the silicon mold is mounted on an inside of the upper surface; an upper block which is assembled with the carrier to form a chamber in which the material and the silicon mold are accommodated; an air cylinder which is connected to the upper surface of the upper block to transmit power so that the upper block descends to be assembled with the carrier and ascends to be separated from the carrier; and a pressing portion which is connected to a side surface of the upper block so as to press the chamber or ventilate the chamber while the upper block and the carrier are assembled with each other.