Abstract: Thermoreversible hydrogels comprsing non-ionic, linear copolymers, and methods of their use in electrophoresis, are provided. The subject copolymers comprise polyacrylamide backbones, where a portion of the acrylamide monomeric units compose hydrogen bonding groups as N-substituents. Combination of the subject copolymers with an aqueous phase provides thermoreversible hydrodgels which find use as separation media in electrophoretic applications.
Type:
Grant
Filed:
January 19, 1996
Date of Patent:
May 20, 1997
Assignee:
Soane BioScience
Inventors:
Alexander P. Sassi, Shi Lin, M. Goretty Alonso-Amigo, Herbert H. Hooper