Patents Assigned to Societa Italo-Britannica L. Manetti-H. Roberts & C.
  • Process for producing a vasal fibrinolytic active principle and the enzymatic product so prepared
    Patent number: 4471053
    Abstract: A natural active principle enzymatic in type, called angiokinase, is obtained with an extraction procedure starting from mammalian connective tissue, such as from cattle and the like. The active principle comprises a new drug for the prophylaxis and treatment of all symptoms of abnormal fibrin formation and thrombus formation in various sites and localizations, such as atherosclerotic diseases and diabetic retinopathy, as well as thrombosis and thromboembolisms.
    Type: Grant
    Filed: April 7, 1982
    Date of Patent: September 11, 1984
    Assignee: Societa Italo-Britannica L. Manetti-H. Roberts & C.
    Inventors: Gaetano Comi, Maurizio Pandolfi
  • L-Arginine D,L-pyroglutamate as a pharmaceutical agent having an activity at the neuro-endocrinal level
    Patent number: 4388325
    Abstract: L-arginine D,L-pyroglutamate has a tonic activity at the neuro-endocrinal level with a specific effect in enhancing sexual behavior of Mammalia males, particularly in individuals of elderly age, humans being included. To be used in the pharmaceutical and veterinary field.
    Type: Grant
    Filed: June 22, 1981
    Date of Patent: June 14, 1983
    Assignee: Societa' Italo-Britannica L. Manetti-H. Roberts & C.
    Inventor: Giovanni Orzalesi
  • Process for the preparation of 2-(4-isobutylphenyl)-propiohydroxamic acid
    Patent number: 4061668
    Abstract: 2-(4-Isobutylphenyl)-propiohydroxamic acid is prepared by mixing anhydrous methanol with 2-(4-isobutylphenyl)-propionitrile, saturating the mixture with dry hydrogen chloride, reacting, diluting the reaction product with ethyl ether, reacting the precipitate with hydroxylamine hydrochloride in methanol and with 50% NaOH, stirring, diluting with water and precipitating with carbon dioxide.
    Type: Grant
    Filed: October 19, 1976
    Date of Patent: December 6, 1977
    Assignee: Societa Italo-Britannica L. Manetti - H. Roberts & C.
    Inventors: Giovanni Orzalesi, Renato Selleri
  • Inhibitor of blood plate aggregation
    Patent number: 3973026
    Abstract: There is prepared the compound N,N'-bis-(3-picolyl)-4-methoxy-isophthalamide. It is useful as an inhibitor of blood plate aggregation.
    Type: Grant
    Filed: February 5, 1975
    Date of Patent: August 3, 1976
    Assignee: Societa Italo-Britannica L. Manetti-H. Roberts & C.
    Inventors: Giovanni Orzalesi, Renato Selleri