Patents Assigned to Societe d'Etudes de Produits Chimiques
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Patent number: 4346100Abstract: This invention relates to a new phenoxy acetic acid derivative, to a method for its preparation and to therapeutic compositions containing it.Type: GrantFiled: April 17, 1978Date of Patent: August 24, 1982Assignee: Societe d'Etudes de Produits ChimiquesInventor: Andre Esanu
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Patent number: 4344947Abstract: A method for the chemotherapy of muscular dystrophy which includes administrating an effective amount of 2 isopropylaminopyrimidine.Type: GrantFiled: October 29, 1980Date of Patent: August 17, 1982Assignee: Societe d'Etudes de Produits ChimiquesInventor: Pierre M. Huve
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Patent number: 4297495Abstract: The invention provides a process for the preparation of 2-isopropylamino-pyrimidine, the process comprising reacting bis(isopropylguanidine)sulphate with 1,1,3,3-tetraethoxy-propane in stoichiometric proportions at 40.degree.-60.degree. C., in acidic aqueous solution.Type: GrantFiled: June 30, 1980Date of Patent: October 27, 1981Assignee: Societe d'Etudes de Produits ChimiquesInventor: Andre Esanu
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Patent number: 4267181Abstract: The invention relates to new isopropylamino pyrimidine halogeno derivatives of the formula: ##STR1## in which X represents a fluorine, a chlorine or a bromine atom. These compounds, when X stands for chlorine or bromine, are prepared by reacting, at room temperature and in stoichiometric proportions, 2-isopropylamino pyrimidine on the appropriate N-halogeno succinimide, in the presence of acetic acid.Type: GrantFiled: April 28, 1980Date of Patent: May 12, 1981Assignee: Societe d'Etudes de Produits ChimiquesInventor: Andre Esanu
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Patent number: 4266058Abstract: The present invention provides a process for the synthesis of 2-isopropylamino-pyrimidine by aminolysis of 2-methylsulphonyl-pyrimidine using isopropylamine. The aminolysis is effected, according to the present invention, by refluxing isopropylamine and 2-methylsulphonyl-pyrimidine in the absence of a solvent. Using this technique, the 2-isopropylamino-pyrimidine has been obtained in a substantially quantitative yield.Type: GrantFiled: June 23, 1980Date of Patent: May 5, 1981Assignee: Societe d'Etudes de Produits ChimiquesInventors: Claude G. Demosthene, Christian R. Aspisi
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Patent number: 4256767Abstract: A new phenoxy alkylamide is disclosed. The compound has been found to have beneficial activity in the field of immuno-stimulation.Type: GrantFiled: June 19, 1979Date of Patent: March 17, 1981Assignee: Societe d'Etudes de Produits ChimiquesInventor: Andre Esanu
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Patent number: 4254162Abstract: A therapeutic use for a phenoxy acetic acid is disclosed. The compound is effective as a choleretic agent and can be administered orally or intravenously.Type: GrantFiled: November 21, 1979Date of Patent: March 3, 1981Assignee: Societe d'Etudes de Produits ChimiquesInventor: Andre Esanu
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Patent number: 4183926Abstract: New phenothiazine derivatives having pharmaceutical activity are disclosed. The compounds are of particular interest because of their neuroleptic activity. The compounds are suitably prepared by reacting an N-substituted phenothiazine with an O,O'-isopropylidenyl-2-methyl-3-hydroxy-4-hydroxymethyl-5-(N-piperazinylme thyl)-pyridine.Type: GrantFiled: November 17, 1977Date of Patent: January 15, 1980Assignee: Societe d'Etudes de Produits ChimiquesInventor: Andre Esanu
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Patent number: 4176193Abstract: A method of treating hyperlipemia, hypertriglyceridemia and hypercholesterodemia is disclosed. The treatment comprises the administration in a pharmaceutically acceptable carrier of an effective amount of a p-halo-N-cyanoalkyl isobutyramide.Type: GrantFiled: November 17, 1978Date of Patent: November 27, 1979Assignee: Societe d'Etudes de Produits ChimiquesInventor: Andre Esanu
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Patent number: 4137316Abstract: A new vincamine salt of therapeutic interest is disclosed. The salt is vincamine pyridoxal 5-phosphate and exhibits surprisingly greater activity than vincamine alone. A process for the preparation of the compound is also disclosed.Type: GrantFiled: May 9, 1977Date of Patent: January 30, 1979Assignee: Societe d'Etudes de Produits ChimiquesInventor: Andre Esanu
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Patent number: 4131617Abstract: A process for the preparation of an isobutyramide is disclosed. A sodium phenolate is prepared by reacting sodium with a phenol in ethanol, an excess of toluene is added to the solution to form an ethanol/toluene azeotrope which azeotrope is then removed by distillation whereafter a N-cyanoalkyl .alpha.-bromo-isobutyramide is added, the mixture is refluxed for a period of 6-15 hours after which water is added to form a precipitate which is then removed from the reaction mixture.Type: GrantFiled: March 17, 1977Date of Patent: December 26, 1978Assignee: Societe d'Etudes de Produits ChimiquesInventor: Andre Esanu
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Patent number: 4100287Abstract: A new pharmaceutical compound having analgesic activity is disclosed. The compound is N-2, 6-dichloro-phenyl-2-aminopyrimidine. A method of preparing the compound is also disclosed as is a therapeutic composition which includes the compound.Type: GrantFiled: August 30, 1977Date of Patent: July 11, 1978Assignee: Societe d'Etudes de Produits ChimiquesInventor: Andre Esanu
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Patent number: 4073895Abstract: A therapeutic composition of matter presenting a favorable action in the field of nerve regeneration is disclosed. An effective amount of 2-isopropylamino pyrimidine orthophosphate is incorporated in an appropriate carrier. Also disclosed is a process of producing the orthophosphate of 2-isopropylamino pyrimidine.Type: GrantFiled: February 16, 1977Date of Patent: February 14, 1978Assignee: Societe d'Etudes de Produits ChimiquesInventor: Andre Esanu
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Patent number: 3984414Abstract: Dichloro acetate of 2-isopropyl amino pyrimidine is an active ingredient in drug for the treatment of neuropathies.Type: GrantFiled: November 19, 1974Date of Patent: October 5, 1976Assignee: Societe d'Etudes de Produits ChimiquesInventor: Andre Esanu
