Abstract: New substituted benzamides have the general formula: ##STR1## their optical isomers and their physiologically acceptable salts. The compounds are used as activators of the central nervous system.
Type:
Grant
Filed:
March 13, 1989
Date of Patent:
April 3, 1990
Assignee:
Societe d'Etudes Scientifiques et Industrielle de l'Ile-d-France
Inventors:
Jacques Acher, Jean-Claude Monier, Jean-Paul Schmitt, Gardaix-Luthereau Renee, Brenda Costall, Robert Naylor
Abstract: The invention concerns a novel process for the synthesis of N-[(1'-allyl-2'-pyrrolidinyl) methyl]-2-methoxy-4,5-azimidobenzamide, which successively comprises the preparation of 2-methoxy-4,5-diaminobenzoic acid, 2-methoxy-4,5-diacetylaminobenzoic acid, N-(2',5'-dihalopentyl)-2-methoxy-4,5-diacetylaminobenzamide, N-[(1'-allyl-2'-pyrrolidinyl) methyl]-2-methoxy-4,5-diacetylaminobenzamide and then N-[(1'-allyl-2'-pyrrolidinyl) methyl]-2-methoxy-4,5-azimido benzamide.
Type:
Grant
Filed:
December 18, 1985
Date of Patent:
February 14, 1989
Assignee:
Societe D'Etudes Scientifiques et Industrielles de L'Ile-d-France