Patents Assigned to Societe de Conseils de Recherches et d'Applications (S.C.R.A.S.)
  • Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 7553976
    Abstract: The invention relates to new derivatives of 2-(iminomethyl)amino-phenyl which are NO synthase inhibitors and can trap reactive oxygen species. These compounds can notably be used for the treatment of stroke, of neurodegenerative diseases and of ischemic or hemorragic cardiac of cerebral infarctions.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: June 30, 2009
    Assignee: Societe de Conseils de Recherches et d'Applications (S.C.R.A.S.)
    Inventors: Pierre Etienne Chabrier De Lassauniere, Serge Auvin, Dennis Bigg, Michel Auquet, Jeremiah Harnett
  • Benzothiazole-4,7-diones and benzoxazole-4,7-diones with substituents in position 5 or 6 and method for production thereof
    Patent number: 7335674
    Abstract: A targetted production method for benzothiazole-4,7-dione and benzoxazole-4,7-dione derivatives, mono-substituted in the 5 or 6 position with an amino group, itself optionally substituted.
    Type: Grant
    Filed: June 24, 2004
    Date of Patent: February 26, 2008
    Assignee: Societe de Conseils de Recherches et d'Applications (S.C.R.A.S.)
    Inventors: Marie-Odile Galcera Contour, Olivier Lavergne
  • Process for the preparation of microballs and microballs thus obtained
    Patent number: 5569467
    Abstract: A method of making microballs is disclosed. An active ingredient, a biocompatible polymer and a supporting phase, such as silicone oil, are stirred at a temperature above the Tg of the polymer and below the temperature at which any of the ingredients vaporizes or degrades. Stirring is continued until microballs of the desired diameter are formed, whereafter the mixture is cooled and the microballs are separated from the supporting phase. The microballs are substantially spherical, substantially smooth on their external surface and have substantially no active ingredient on their external surface.
    Type: Grant
    Filed: May 16, 1994
    Date of Patent: October 29, 1996
    Assignee: Societe de Conseils de Recherches et d'Applications (S.C.R.A.S.)
    Inventor: Jean-Marc Ruiz
  • Ophthalmological composition of matter and a method for treatment of ocular inflammation by said composition
    Patent number: 4897421
    Abstract: The present invention relates to an ophthalmological composition of matter comprising a suspension of eicosapentaenoic acid in an alkyl cellulose and/or hydroxyalkyl aqueous cellulose solution to be used in any case of ocular inflammation on men and/or on aminals.The invention also relates to the use of said eicosapentaenoic acid and to a method for the treatment of ocular inflammation by the same.
    Type: Grant
    Filed: May 6, 1988
    Date of Patent: January 30, 1990
    Assignee: Societe De Conseils de Recherches et D'Application (S.C.R.A.S.)
    Inventor: Pierre Braquet