Patents Assigned to Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
  • Patent number: 8348881
    Abstract: The invention concerns a device for injecting a solid medicine (10) comprising a body (2) inside which moves along a general forward moving axis (X-X) a bevelled (34) needle (4) wherein is introduced the medicine (10), said injection device (1) further comprising retaining means for preventing the medicine from falling (10) prior to being injected. The invention is characterized in that the medicine (10) is retained through an elastic deformation imparted to the needle (4) by the retaining means or by an elastic deformation of the retaining means themselves, or still by the combined flexibility of those two means.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: January 8, 2013
    Assignee: Société de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S) SAS
    Inventors: Christophe Aubert, Roland Cherif-Cheikh, Thierry Rimlinger, Fabrice Bonacci, Serge Barneaud
  • Patent number: 7897578
    Abstract: The present invention relates to peptides with anti-proliferative activity, of sequence SEQ ID No. 1, SEQ ID No. 2 or SEQ ID No. 3.
    Type: Grant
    Filed: June 11, 2007
    Date of Patent: March 1, 2011
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Eric Ferrandis, José-Antonio Camara Y Ferrer, Jean-Grégoire Marin
  • Publication number: 20100144714
    Abstract: The present invention relates to new derivatives of imidazo, pyrimido and diazepine-pyrimidine-dione of the general formula (I) in which R1, R2, L1, L2, Y, Z and A are various and varying groups. These products exhibit a good affinity for certain sub-types of cannabinoid receptors, in particular the CB2 receptors. They are particularly useful for treating pathological conditions and diseases in which one or more cannabinoid receptors are involved. The invention also relates to pharmaceutical compositions containing said products, and to the use thereof for preparing a drug.
    Type: Application
    Filed: December 17, 2007
    Publication date: June 10, 2010
    Applicant: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)
    Inventors: Lydie Poitout, Valérie Brault
  • Publication number: 20100036120
    Abstract: The invention concerns a novel method for synthesis of 1,4-morpholine-2,5-diones of formula (I), wherein: R, R1, R2, R3 and R4 independently represent various radicals, by oxidizing the ketone function of a cyclic compound of formula (II).
    Type: Application
    Filed: January 24, 2007
    Publication date: February 11, 2010
    Applicant: Societe de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Didier Bourissou, Blaca Martin-Vaca, Sylvie Moebs-Sanchez, Coralie Ivens, Roland Cherif-cheikh, Anne-Paula De Sousa Delgado
  • Patent number: 7655438
    Abstract: A process for preparing recombinant heterocarpine with the complete sequence of heterocarpine (SEQ. ID. NO. 10), expression vectors comprising a polynucleotide encoding for heterocarpine, host cells transformed or transfected by said expression vectors as well as a process for obtaining heterocarpine by means of said transformed or transfected host cells are described where in the recombinant heterocarpine obtained is used to treat cancer.
    Type: Grant
    Filed: December 9, 2003
    Date of Patent: February 2, 2010
    Assignee: Societe de Conseils de Recherches et d'Application Scientifiques (S.C.R.A.S.)
    Inventor: Eric Ferrandis
  • Publication number: 20090275624
    Abstract: A subject of the present invention is novel compounds comprising 2 or 3 benzothiazole-4,7-dione- or benzooxazole-4,7-dione-type units, which inhibit the cdc25 phosphatases, in particular cdc25-C phosphatase. These compounds can in particular be used in the treatment of cancer.
    Type: Application
    Filed: December 16, 2005
    Publication date: November 5, 2009
    Applicant: Societe de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Marie-Odile Galcera-Contour, Dennis Bigg, Grégoire Prevost, Alban Sidhu
  • Publication number: 20090270400
    Abstract: The invention relates to a product comprising (1R)-1-[(({2R)-2-amino-3-[(8S)-8-(cyclohexylmethyl) -2-phenyl-5,6-dihydroimidazo [1,2-a]pyrazin-7(8H)-yl]-3-oxopropyl}dithio)methyl]-2-[(8S)-8-(cyclohexylmethyl) -2-phenyl-5,6-dihydrolmidazo[1,2-a]pyrazin-7(8H)-yl]-2-oxoethylamine in association with an analgesic agent selected from morphine, the similar or a morphine derivative, sodium channel inhibitors, non-steroidal antiflammatory agents (AINS), glutamatergic system inhibitors, tricycle antidepressants and gabaergic derivatives for simultaneous therapeutic use which is separated or out over the time for pain treatment or prevention.
    Type: Application
    Filed: December 16, 2005
    Publication date: October 29, 2009
    Applicant: Societe de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Michel Auguet, Christine Favre, Gregoire Prevost, Pierre-Etienne Chabrier De Lassauniere
  • Publication number: 20090209466
    Abstract: The present invention relates to peptides with anti-proliferative activity, of sequence SEQ ID No. 1, SEQ ID No. 2 or SEQ ID No. 3.
    Type: Application
    Filed: June 11, 2007
    Publication date: August 20, 2009
    Applicant: Societe de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Eric Ferrandis, José-Antonio Camara Y Ferrer, Jean-Grégoire Marin
  • Publication number: 20090209903
    Abstract: The invention relates to a device which is used to inject an implant (6) into tissues (50). The inventive device is characterized in that it comprises : a main hollow body (2; 2?) having a hollow needle (4; 4?) fixed thereto, into which the implant (6) is introduced; a secondary body (26; 26?) which is disposed coaxially inside the main body (2; 2?) and which surrounds the needle (4; 4?); and a plunger rod (36; 36?) which can slide coaxially inside the hollow needle (4; 4?).
    Type: Application
    Filed: November 15, 2005
    Publication date: August 20, 2009
    Applicant: Société de Conseils de Recherches et d'Application Scientifiques (S.C.R.A.S.) SAS
    Inventors: Roland Cherif-Cheikh, Christophe Aubert, Thierry Rimlinger, Fabrice Bonacci, Serge Barneaud
  • Publication number: 20090186930
    Abstract: The invention concerns novel imidazole derivatives of general formula (I), wherein Z? and Z represent different variable groups. Said products have an antitumoral activity. The invention also concerns pharmaceutical compositions containing said products and their use for preparing antitumoral medicine.
    Type: Application
    Filed: April 26, 2007
    Publication date: July 23, 2009
    Applicant: Societe de Conseils de Recherches et D' Applications Scientifiques (S.C.R.A.S.)
    Inventors: Anne-Marie Liberatore, Dennis Bigg, Dominique Pons, Grégoire Prevost
  • Publication number: 20090186052
    Abstract: The invention concerns the use or a fragment of botulinum toxin having said toxin activity for preparing a medicine for reversibly desensitizing an area of the skin, said skin area being designed to receive injections. Said injections can be related, for example, to repeated delivery of insulin, growth hormones or other medicines in injectable form.
    Type: Application
    Filed: December 21, 2005
    Publication date: July 23, 2009
    Applicant: Societe de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventor: Roland Cherif-Cheikh
  • Publication number: 20090137596
    Abstract: A subject of the invention is a product comprising at least one Cdc25 phosphatase inhibitor in combination with at least one other anti-cancer agent for a therapeutic use which is simultaneous, separate or spread over time in the treatment of cancer.
    Type: Application
    Filed: October 7, 2008
    Publication date: May 28, 2009
    Applicant: Societe de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Gregoire PREVOST, Marie-Christine Brezak Pannetier, Christian Diolez
  • Publication number: 20090131428
    Abstract: The invention concerns the use as cdc25 phosphatase inhibitors, in particular cdc25-C phosphatase, and CD45 phosphatase, of compounds of general formula (I), wherein: W represents O or S. In accordance with the invention, the compounds of general formula (I) can in particular be used for preparing a medicine for cancer treatment.
    Type: Application
    Filed: October 6, 2008
    Publication date: May 21, 2009
    Applicant: Societe de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Marie-Odile Galcera Contour, Olivier Lavergne, Marie-Christine Brezak Pannetier, Gregoire Prevost
  • Patent number: 7534805
    Abstract: Novel imidazole compounds of the formula wherein the substituents are as defined in the application having antitumoral activity and use thereof.
    Type: Grant
    Filed: May 26, 2004
    Date of Patent: May 19, 2009
    Assignee: Societe de Conseils de Recherches Et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Anne-Marie Liberatore, Dominique Pons
  • Publication number: 20090082345
    Abstract: The invention concerns the use as cdc25 phosphatase inhibitors, in particular cdc25-C phosphatase, and CD45 phosphatase, of compounds of general formula (I), wherein: W represents O or S. In accordance with the invention, the compounds of general formula (I) can in particular be used for preparing a medicine for cancer treatment.
    Type: Application
    Filed: October 3, 2008
    Publication date: March 26, 2009
    Applicant: Societe de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Marie-Odile GALCERA CONTOUR, Olivier Lavergne, Marie-Christine Brezak Pannetier, Gregoire Prevost
  • Patent number: 7501524
    Abstract: A compound of the formula wherein the substituents are as defined in the specification and pharmaceutical salts thereof having a good affinity for sub-types of melanocortin receptors making them useful for treating diseases in which such receptors are included such as pain, inflammatory conditions, etc.
    Type: Grant
    Filed: August 11, 2004
    Date of Patent: March 10, 2009
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Lydie Poitout, Valerie Brault, Carole Sackur, Pierre Roubert, Pascale Plas
  • Patent number: 7501525
    Abstract: A subject of the present Application is novel derivatives of benzimidazole and imidazo-pyridine which have a good affinity for certain sub-types of melanocortin receptors, in particular the MC4 receptors. They are particularly useful for treating pathological conditions and diseases in which one or more melanocortin receptors are involved. The invention also relates to pharmaceutical compositions containing said products.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: March 10, 2009
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Lydie Poitout, Valerie Brault, Carole Sackur, Pierre Roubert, Pascale Plas
  • Patent number: 7495110
    Abstract: A subject of the present application is new benzimidazole derivatives of formula in which A, Y, R1, R2, R3 and R4 represent different variable groups. These products have an antagonist activity of GnRH (Gonadotropin-Releasing Hormone). The invention also relates to pharmaceutical compositions containing said products and their use for the preparation of a medicament.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: February 24, 2009
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Lydie Poitout, Valérie Brault, Eric Ferrandis, Christophe Thurieau
  • Patent number: 7495021
    Abstract: The invention concerns the use as cdc25 phosphatase inhibitors, in particular cdc25-C phosphatase, and CD45 phosphatase, of compounds of general formula (I), wherein: W represents O or S. In accordance with the invention, the compounds of general formula (I) can in particular be used for preparing a medicine for cancer treatment.
    Type: Grant
    Filed: August 31, 2007
    Date of Patent: February 24, 2009
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Marie-Odile Galcera Contour, Olivier Lavergne, Marie-Christine Brezak Pannetier, Grégoire Prevost
  • Patent number: 7495009
    Abstract: Derivatives of imidazopyridine which have a good affinity for certain sub-types of melanocortin receptors, in particular MC4 receptors and are useful for treating pathological states and diseases in which one or more melanocortin receptors are involved and pharmaceutical compositions containing said products.
    Type: Grant
    Filed: March 29, 2004
    Date of Patent: February 24, 2009
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Lydie Poitout, Valérie Brault, Carole Sackur, Pierre Roubert, Pascale Plas