Abstract: The present invention pertains to biodegradable polymers comprising a non-polymerizable lactone, biodegradable compositions comprising the polymer and a therapeutic agent the use of the compositions for the sustained release of therapeutic agents, wherein the therapeutic agent is reversibly immobilized on the polymer matrix using ionic complexation between the latent carboxylic groups present on the lactone bearing polymer matrix and a cationic group on the therapeutic agent.
Type:
Grant
Filed:
November 2, 1999
Date of Patent:
October 18, 2005
Assignee:
Societe de Conseils de Recherches et d'Applications Scientifiques, SAS of Paris