Patents Assigned to Societe de Conseils de Recherches et
  • Patent number: 4569938
    Abstract: This invention relates to new 1,3-dihydro-6-methyl-furo-(3,4-c)-pyridine derivatives of the general formula: ##STR1## wherein, each of A.sub.1 and A.sub.2 represents various hydrocarbon groups, to pharmaceutically acceptable salts of them, to a process for the preparation of said derivatives from the corresponding 6-hydroxy compounds, treated by ethyl bromoacetate and then hydrolyzed. The invention further provides pharmaceutical compositions wherein said derivatives are used as active ingredients. The compounds are useful as diuretics, in lowering blood pressure and as antihistaminics.
    Type: Grant
    Filed: November 5, 1984
    Date of Patent: February 11, 1986
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques
    Inventor: Andre Esanu
  • Patent number: 4569939
    Abstract: This invention relates to new 1,3-dihydro-6-vinyl-7-hydroxy-furo-(3,5-c)-pyridine derivatives of the general formula: ##STR1## wherein each of A.sub.1 and A.sub.2 independently represents various hydrocarbon substituents, to a process for the preparation of these compounds from the corresponding 7-chloromethyl derivative and to pharmaceutical composition containing them. The compounds are useful as diuretics.
    Type: Grant
    Filed: November 5, 1984
    Date of Patent: February 11, 1986
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques
    Inventor: Andre Esanu
  • Patent number: 4492701
    Abstract: This invention relates to the 2-isopropylamino-pyrimidine-N-oxide of the formula: ##STR1## to a preparation process of the same consisting in submitting at 15.degree. to 45.degree. C., 2-isopropylamino pyrimidine to a smooth oxidation by stoichiometric proportions or a slight excess of up to 10% of an appropriate oxidizing agent and to a therapeutic composition of matter comprising said compound as an active ingredient therein.
    Type: Grant
    Filed: September 29, 1982
    Date of Patent: January 8, 1985
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques
    Inventor: Andre Esanu
  • Patent number: 4383998
    Abstract: This invention relates to new 1,3-dihydro-6-methyl-7-hydroxy-furo-(3,4-c)-pyridine derivatives of the general formula ##STR1## wherein A< represents a group of the formula --(CH.sub.2).sub.n --, n being an integer of from 1 to 5, or a homocyclic or heterocyclic group, and R represents a hydrogen, chlorine or fluorine atom, a trifluoromethyl group, an alkyl group having from 1 to 5 carbon atoms, an alkoxy group having from 1 to 5 carbon atoms, a alkylthio group having from 1 to 5 carbon atoms, a dialkylaminoalkoxy group in which the alkyl groups each have from 1 to 5 carbon atoms and the alkoxy group has from 1 to 5 carbon atoms or a N-pyrolidinyl-alkoxy group in which the alkoxy group has from 1 to 5 carbon atoms to a process for the preparation of the same by refluxing .alpha..sup.
    Type: Grant
    Filed: January 8, 1982
    Date of Patent: May 17, 1983
    Assignee: Societe de Conseils de Recherches et D'Applications Scientifiques
    Inventor: Andre Esanu