Abstract: To provide a ceramic particle separable composite material having a calcium phosphate sintered body particle with which bioaffinity reduction and solubility change are suppressed as much as possible and which has a smaller particle diameter. A ceramic particle separable composite material comprising a ceramic particle and a substrate, wherein: the ceramic particle and the substrate are chemically bonded to each other, or the ceramic particle physically adheres to or is embedded in the substrate; the ceramic particle has a particle diameter within a range of 10 nm to 700 nm; the ceramic particle is a calcium phosphate sintered body particle; and the ceramic particle contains no calcium carbonate.

Abstract: This invention provides a measure that makes it possible to prevent more effectively, in comparison with the prior art, the invasion of germs from the gap between a dental prosthesis and the gingiva when the dental prosthesis is used in an oral cavity as well as the infection and inflammation associated therewith. There is a dental prosthesis or a component thereof, characterized in that: the dental prosthesis or the component thereof has hydroxyapatite fine particles on a surface of the dental prosthesis or the component thereof; the hydroxyapatite fine particles are sintered bodies; and the hydroxyapatite fine particles have a mean particle size of 10 to 1,000 nm.

Abstract: This invention has an object to provide a means for providing a calcium phosphate sintered body particle group that does not cause a phenomenon of bubble generation in any use mode thereof, and further has a smaller particle diameter. There is provided a ceramic particle group containing spherical ceramic particles, which is characterized in that the ceramic particle has a particle diameter within a range of 10 nm to 700 nm, and is a calcium phosphate sintered body particle, and further the ceramic particle group contains no calcium carbonate.

Abstract: To provide a technology for sintering calcium phosphate to manufacture a calcium phosphate sintered body and suppressing generation of calcium oxide when calcium phosphate is sintered, there is provided a process for manufacturing a sintered calcium phosphate molded body is characterized by including a step for heating a composition containing at least a composite of calcium phosphate fine particles and polyether and sintering the calcium phosphate fine particles.

Abstract: An adsorbent, which can be produced by a method in which a particle size, a pore size, a specific surface area or the like can be easily controlled, and is suitable for isolation of biomolecules. The adsorbent contains aggregates of calcium phosphate-based particles, and has an average pore size of 15 to 36 nanometers and a specific surface area of 40 to 90 m2/mL when measurement is carried out by mercury porosimetry.

Abstract: This invention has an object to provide a means for providing a calcium phosphate sintered body particle group that does not cause a phenomenon of bubble generation in any use mode thereof, and further has a smaller particle diameter. There is provided a ceramic particle group containing spherical ceramic particles, which is characterized in that the ceramic particle has a particle diameter within a range of 10 nm to 700 nm, and is a calcium phosphate sintered body particle, and further the ceramic particle group contains no calcium carbonate.

Abstract: An inner surface-modified tube includes fine particles that are buried in an inner surface of a tube with part of surfaces of the fine particles exposed, wherein the fine particles are unevenly distributed such that more fine particles are distributed in a region from a center of the tube to the inner surface of the tube than in a region from the center of the tube to an outer surface of the tube based on a thickness direction of the tube, an arithmetic average roughness Ra of the inner surface of the tube is 1 nm or more and 100 ?m or less, a particle diameter of each fine particle is 10 nm or more and 100 ?m or less, and an inner diameter of the tube is 0.01 mm or more and 100 mm or less.

Abstract: To provide a technology for sintering calcium phosphate to manufacture a calcium phosphate sintered body and suppressing generation of calcium oxide when calcium phosphate is sintered, there is provided a process for manufacturing a sintered calcium phosphate molded body is characterized by including a step for heating a composition containing at least a composite of calcium phosphate fine particles and polyether and sintering the calcium phosphate fine particles.

Abstract: This invention provides a measure that makes it possible to prevent more effectively, in comparison with the prior art, the invasion of germs from the gap between a dental prosthesis and the gingiva when the dental prosthesis is used in an oral cavity as well as the infection and inflammation associated therewith. There is a dental prosthesis or a component thereof, characterized in that: the dental prosthesis or the component thereof has hydroxyapatite fine particles on a surface of the dental prosthesis or the component thereof; the hydroxyapatite fine particles are sintered bodies; and the hydroxyapatite fine particles have a mean particle size of 10 to 1,000 nm.

Abstract: To provide a method for producing a porous calcium phosphate body having open micro-pores, by the method for producing the porous calcium phosphate body, in which calcium phosphate is subjected to electro-spinning.

Abstract: An adsorbent, which can be produced by a method in which a particle size, a pore size, a specific surface area or the like can be easily controlled, and is suitable for isolation of biomolecules. The adsorbent contains aggregates of calcium phosphate-based particles, and has an average pore size of 15 to 36 nanometers and a specific surface area of 40 to 90 m2/mL when measurement is carried out by mercury porosimetry.

Abstract: A method for repairing a tooth surface having scratches and hollow portions formed on a tooth enamel surface includes administering a tooth surface repairing material to a dental disease patient. The tooth surface repairing material contains a highly crystalline sintered fine calcium phosphate particle having an average particle diameter in the range of 20 to 100 nm.

Abstract: An inner surface-modified tube includes fine particles that are buried in an inner surface of a tube with part of surfaces of the fine particles exposed, wherein the fine particles are unevenly distributed such that more fine particles are distributed in a region from a center of the tube to the inner surface of the tube than in a region from the center of the tube to an outer surface of the tube based on a thickness direction of the tube, an arithmetic average roughness Ra of the inner surface of the tube is 1 nm or more and 100 ?m or less, a particle diameter of each fine particle is 10 nm or more and 100 ?m or less, and an inner diameter of the tube is 0.01 mm or more and 100 mm or less.

Abstract: Provided is a means for fixing calcium phosphate onto the surface of a metal by a treatment method which uses no acid and produces less residue. A method of producing a calcium phosphate composite in which calcium phosphate is bonded to the surface of a base material, the method including a surface treatment step of bringing the surface of the base material into contact with a surface treating agent, and then into contact with a silane coupling agent, to surface treat the base material; a polymerization step of initiating, after the surface treatment step, polymerization of the silane coupling agent by means of a polymerization initiator; and a bonding step of bonding the silane coupling agent at the surface of the base material after the polymerization step, with calcium phosphate; wherein the base material is a metal, and the surface treating agent is ozone water.

Abstract: [Object] To provide a biodegradable material that has sufficient mechanical strength, considering in vivo use also, and that can suppress pH changes caused by acidic degradation products. [Solving Means] Provided is a biodegradable material using polyester as a base material, including calcium phosphate particles having an average particle diameter of 10 to 1000 nm.

Abstract: Provided is a functional nonwoven fabric that has good feeling upon use, such as hand feeling (softness) or texture, and is capable of stably exhibiting the characteristics of hydroxyapatite (for example, microbe adsorption property). Disclosed is a functional nonwoven fabric in which sintered hydroxyapatite particles are fixed by thermal fusion bonding to a surface of a nonwoven fabric containing fibers, at least surfaces of the fibers being mainly composed of a thermoplastic resin, wherein a shearing rigidity of the functional nonwoven fabric is 8.5 gf/cm/degree or less.

Abstract: To provide a method for producing a porous calcium phosphate body having open micropores. A porous calcium phosphate body having open and uniform micropores can be produced by the method for producing the porous calcium phosphate body, in which calcium phosphate is subjected to electrospinning.

Abstract: A method for enlarging a breast includes the step of administering to a subject in need thereof a composition that includes a fine particle of calcium phosphate. The fine particle of calcium phosphate may be a fine particle of hydroxyapatite. An average particle size of the fine particle of calcium phosphate is 10 to 1,000 nm. The fine particle of calcium phosphate may be a sintered body. The sintered body may be manufactured by a method including: a mixing step in which a primary particle containing calcium phosphate is mixed with a fusion inhibitor, and a sintering step in which the mixed particle obtained by the mixing step defined above is exposed to a sintering temperature.

Abstract: A collagen production enhancer for increasing the amount of collagen contained in the skin tissues, comprising calcium phosphate fine particles as effective ingredients.

Abstract: Provided is a means for fixing calcium phosphate onto the surface of a metal by a treatment method which uses no acid and produces less residue. A method of producing a calcium phosphate composite in which calcium phosphate is bonded to the surface of a base material, the method including a surface treatment step of bringing the surface of the base material into contact with a surface treating agent, and then into contact with a silane coupling agent, to surface treat the base material; a polymerization step of initiating, after the surface treatment step, polymerization of the silane coupling agent by means of a polymerization initiator; and a bonding step of bonding the silane coupling agent at the surface of the base material after the polymerization step, with calcium phosphate; wherein the base material is a metal, and the surface treating agent is ozone water.