Patents Assigned to Solasia Pharma K.K.
  • Organoarsenic compounds and methods for the treatment of cancer
    Patent number: 11324714
    Abstract: A method for treating a lymphoma selected from non-Hodgkin's and Hodgkin's lymphoma comprising administering an organoarsenic compound having a structure of the formula (I) wherein X is S or Se and R1 and R2 are independently C1-30alkyl (R3, R3?, R4, R5, W and “n” are as defined in claim 1) in particular where the compound is S-dimethylarsinoglutathione, N-(2-S-dimethylarsinothiopropionyl)glycine, 2-amino-3-(dimethylarsino)thio-3-methylbutanoic acid, S-dimethylarsino-thiosuccinic acid or S-dipropylarsino-1-thioglycerol.
    Type: Grant
    Filed: October 15, 2020
    Date of Patent: May 10, 2022
    Assignee: SOLASIA PHARMA K.K.
    Inventors: Brian Eric Schwartz, Jonathan Lewis, Philip B. Komarnitsky
  • Organoarsenic compounds and methods for the treatment of cancer
    Patent number: 11324713
    Abstract: A method for treating a lymphoma selected from non-Hodgkin's and Hodgkin's lymphoma comprising administering an organoarsenic compound having a structure of the formula (I) wherein X is S or Se and R1 and R2 are independently C1-30alkyl (R3, R3?, R4, R5, W and “n” are as defined in claim 1) in particular where the compound is S-dimethylarsinoglutathione, N-(2-S-dimethylarsinothiopropionyl)glycine, 2-amino-3-(dimethylarsino)thio-3-methylbutanoic acid, S-dimethylarsino-thiosuccinic acid or S-dipropylarsino-1-thioglycerol.
    Type: Grant
    Filed: October 15, 2020
    Date of Patent: May 10, 2022
    Assignee: SOLASIA PHARMA K.K.
    Inventors: Brian Eric Schwartz, Jonathan Lewis, Philip B. Komarnitsky
  • ORGANOARSENIC COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER
    Publication number: 20210038556
    Abstract: A method for treating a lymphoma selected from non-Hodgkin's and Hodgkin's lymphoma comprising administering an organoarsenic compound having a structure of the formula (I) wherein X is S or Se and R1 and R2 are independently C1-30alkyl (R3, R3?, R4, R5, W and “n” are as defined in claim 1) in particular where the compound is S-dimethylarsinoglutathione, N-(2-S-dimethylarsinothiopropionyl)glycine, 2-amino-3-(dimethylarsino)thio-3-methylbutanoic acid, S-dimethylarsino-thiosuccinic acid or S-dipropylarsino-1-thioglycerol.
    Type: Application
    Filed: October 15, 2020
    Publication date: February 11, 2021
    Applicant: SOLASIA PHARMA K.K.
    Inventors: Brian Eric Schwartz, Jonathan Lewis, Philip B. Komarnitsky
  • ORGANOARSENIC COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER
    Publication number: 20210038557
    Abstract: A method for treating a lymphoma selected from non-Hodgkin's and Hodgkin's lymphoma comprising administering an organoarsenic compound having a structure of the formula (I) wherein X is S or Se and R1 and R2 are independently C1-30alkyl (R3, R3?, R4, R5, W and “n” are as defined in claim 1) in particular where the compound is S-dimethylarsinoglutathione, N-(2-S-dimethylarsinothiopropionyl)glycine, 2-amino-3-(dimethylarsino)thio-3-methylbutanoic acid, S-dimethylarsino-thiosuccinic acid or S-dipropylarsino-1-thioglycerol.
    Type: Application
    Filed: October 15, 2020
    Publication date: February 11, 2021
    Applicant: SOLASIA PHARMA K.K.
    Inventors: Brian Eric Schwartz, Jonathan Lewis, Philip B. Komarnitsky
  • Organoarsenic compounds and methods for the treatment of cancer
    Patent number: 10842769
    Abstract: A method for treating a lymphoma selected from non-Hodgkin's and Hodgkin's lymphoma comprising administering an organoarsenic compound having a structure of the formula (I) wherein X is S or Se and R1 and R2 are independently C1-30alkyl (R3, R3?, R4, R5, W and “n” are as defined in claim 1) in particular where the compound is S-dimethylarsinoglutathione, N-(2-S-dimethylarsinothiopropionyl)glycine, 2-amino-3-(dimethylarsino)thio-3-methylbutanoic acid, S-dimethylarsino-thiosuccinic acid or S-dipropylarsino-1-thioglycerol.
    Type: Grant
    Filed: October 27, 2014
    Date of Patent: November 24, 2020
    Assignee: SOLASIA PHARMA K.K.
    Inventors: Brian Eric Schwartz, Jonathan Lewis, Philip B. Komarnitsky
  • COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER
    Publication number: 20160304546
    Abstract: The present invention relates generally to the field of anti-cancer therapy. More particularly, it provides novel crystalline forms of organic arsenic compounds and methods for their use in treating cancers such as leukemia and solid tumors. Specifically, a crystalline form of darinaparsin, wherein the crystalline form has a melting point in the range of about 190-200 deg C.
    Type: Application
    Filed: December 5, 2014
    Publication date: October 20, 2016
    Applicant: SOLASIA PHARMA K.K.
    Inventor: John C. Amedio, Jr.
  • Compounds and methods for the treatment of cancer
    Patent number: 8865764
    Abstract: The present invention provides organic arsenicals. Many of these compounds have potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: October 21, 2014
    Assignee: Solasia Pharma K.K.
    Inventors: Paul Gutsch, Brian Renzelmann