Patents Assigned to Solmag S.p.A.
  • Process for the preparation of 1-naphthol mixed ethers and intermediates of crystalline forms of (+) and (?)-duloxetine
    Patent number: 7553978
    Abstract: The invention relates to a process for the preparation of duloxetine (1a), comprising the reaction between 1-fluoronaphthalene and 3-N,N-dimethylamino-1-(2-thienyl)-propan-1-ol in the presence of 1,3-dimethyl-2-oxo-hexahydropyrimidine (DMPU) as the solvent; a method for the identification of duloxetine enantiomers and for the determination of its optical purity is also disclosed.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: June 30, 2009
    Assignee: Solmag S.p.A.
    Inventors: Samuele Frigoli, Claudio Fuganti, Roberta Pizzocaro
  • Process for the preparation of Tazarotene
    Patent number: 7273937
    Abstract: Tazarotene is prepared by deoxygenation of the corresponding S-oxide, in turn obtained according to two alternative synthetic pathways.
    Type: Grant
    Filed: March 7, 2006
    Date of Patent: September 25, 2007
    Assignee: Solmag S.p.A.
    Inventors: Samuele Frigoli, Claudio Fuganti, Stefano Serra, Francesco Pizzocaro, Angelo Bedeschi, Paolo Tubertini
  • Process for the preparation of Tazarotene
    Publication number: 20060205950
    Abstract: Tazarotene is prepared by deoxygenation of the corresponding S-oxide, in turn obtained according to two alternative synthetic pathways.
    Type: Application
    Filed: March 7, 2006
    Publication date: September 14, 2006
    Applicant: Solmag S.p.A.
    Inventors: Samuele Frigoli, Claudio Fuganti, Stefano Serra, Francesco Pizzocaro, Angelo Bedeschi, Paolo Tubertini