Patents Assigned to SonoSep Biotech Inc.
  • Patent number: 5711888
    Abstract: Particulate material suspended in a fluid is separated and recycled by means of an ultrasonic resonance wave. In a preferred embodiment, the ultrasonic resonance field is generated within a multilayered composite resonator system including a transducer, the suspension and a mirror parallel to each other. Dimensions and frequencies resonant to the whole system but not exciting Eigen-frequencies of transducer and mirror itself are chosen so that thermal dissipation is minimized. Generally, the process is suitable for all kinds of particles (solid, liquid or gaseous disperse phases) especially for hydrosols (particles in water) and for separation of biological particles such as mammalian, bacterial and plant cells or aggregates. Specialized applications in biotechnology are described including an acoustic filter for mammalian cell bioreactors or the selective retention of viable cells relative to nonviable cells.
    Type: Grant
    Filed: April 4, 1996
    Date of Patent: January 27, 1998
    Assignee: SonoSep Biotech, Inc.
    Inventors: Felix Trampler, Ewald Benes, Wolfgang Burger, Martin Groschl
  • Patent number: 5626767
    Abstract: Particulate material suspended in a fluid is separated and recycled by means of an ultrasonic resonance wave. In a preferred embodiment, the ultrasonic resonance field is generated within a multilayered composite resonator system including a transducer, the suspension and a mirror parallel to each other. Dimensions and frequencies resonant to the whole system but not exciting Eigen-frequencies of transducer and mirror itself are chosen so that thermal dissipation is minimized. Criteria for flow direction and flow rate are defined in order to maintain a high-quality factor of the composite resonator and to achieve a high-separation efficiency. Generally, the process is suitable for all kinds of particles (solid, liquid or gaseous disperse phases) especially for hydrosols (particles in water) and for separation of biological particles such as mammalian, bacterial and plant cells or aggregates.
    Type: Grant
    Filed: July 2, 1993
    Date of Patent: May 6, 1997
    Assignee: SonoSep Biotech Inc.
    Inventors: Felix Trampler, James M. Piret, Stefan A. Sonderhoff, Douglas G. Kilburn
  • Patent number: 5527460
    Abstract: Particulate material suspended in a fluid is separated and recycled by means of an ultrasonic resonance wave. In a preferred embodiment, the ultrasonic resonance field is generated within a multilayered composite resonator system including a transducer, the suspension and a mirror parallel to each other. Dimensions and frequencies resonant to the whole system but not exciting Eigen-frequencies of transducer and mirror itself are chosen so that thermal dissipation is minimized. Generally, the process is suitable for all kinds of particles (solid, liquid or gaseous disperse phases) especially for hydrosols (particles in water) and for separation of biological particles such as mammalian, bacterial and plant cells or aggregates. Specialized applications in biotechnology are described including an acoustic filter for mammalian cell bioreactors or the selective retention of viable cells relative to non-viable cells.
    Type: Grant
    Filed: July 2, 1993
    Date of Patent: June 18, 1996
    Assignee: SonoSep Biotech Inc.
    Inventors: Felix Trampler, Ewald Benes, Wolfgang Burger, Martin Groschl