Patents Assigned to Sonus Pharmaceuticals
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Patent number: 7786164Abstract: Lipophilic di(anticancer drug) compounds, compositions that include the compounds, and methods for treating a cell proliferative disease using the compounds.Type: GrantFiled: December 19, 2006Date of Patent: August 31, 2010Assignee: Sonus Pharmaceuticals, Inc.Inventors: Yuehua Zhang, Lynn C. Gold
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Patent number: 7786134Abstract: Lipophilic anticancer drug compounds, compositions that include the compounds, and methods for treating a cell proliferative disease using the compounds.Type: GrantFiled: December 15, 2006Date of Patent: August 31, 2010Assignee: Sonus Pharmaceuticals, Inc.Inventors: Yuehua Zhang, Lynn C. Gold
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Publication number: 20080045559Abstract: Tocopherol-modified therapeutic drug compounds; emulsion, microemulsion, and micelle formulations that include the compounds; methods for making the compounds and formulations; methods for administering the compounds and formulations; and methods for treating conditions using the compounds and formulations.Type: ApplicationFiled: August 22, 2007Publication date: February 21, 2008Applicant: SONUS PHARMACEUTICALS, INC.Inventors: Yuehua Zhang, Lynn Gold
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Patent number: 7268245Abstract: Multinuclear platinum compounds, compositions that include the platinum compounds, methods for making the platinum compounds, and methods for treating cellular proliferative diseases by administering the platinum compounds.Type: GrantFiled: October 18, 2006Date of Patent: September 11, 2007Assignee: Sonus Pharmaceuticals, Inc.Inventors: Manjari Lal, Lynn C. Gold
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Publication number: 20070207196Abstract: Tocopherol-modified therapeutic drug compounds; emulsion, microemulsion, and micelle formulations that include the compounds; methods for making the compounds and formulations; methods for administering the compounds and formulations; and methods for treating conditions using the compounds and formulations.Type: ApplicationFiled: March 22, 2007Publication date: September 6, 2007Applicant: SONUS PHARMACEUTICALS, INC.Inventor: Yuehua Zhang
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Publication number: 20070142331Abstract: Lipophilic anticancer drug compounds, compositions that include the compounds, and methods for treating a cell proliferative disease using the compounds.Type: ApplicationFiled: December 15, 2006Publication date: June 21, 2007Applicant: SONUS PHARMACEUTICALS, INC.Inventors: Yuehua Zhang, Lynn Gold
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Publication number: 20070141093Abstract: Lipophilic di(anticancer drug) compounds, compositions that include the compounds, and methods for treating a cell proliferative disease using the compounds.Type: ApplicationFiled: December 19, 2006Publication date: June 21, 2007Applicant: Sonus Pharmaceuticals, Inc.Inventors: Yuehua Zhang, Lynn Gold
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Patent number: 7232919Abstract: Platinum compounds, pharmaceutically acceptable salts, and prodrugs thereof. Compositions that include the platinum compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier. Methods for using the platinum compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.Type: GrantFiled: December 19, 2005Date of Patent: June 19, 2007Assignee: Sonus Pharmaceuticals, Inc.Inventor: Manjari Lal
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Publication number: 20070129431Abstract: Multinuclear platinum compounds, compositions that include the platinum compounds, methods for making the platinum compounds, and methods for treating cellular proliferative diseases by administering the platinum compounds.Type: ApplicationFiled: October 18, 2006Publication date: June 7, 2007Applicant: SONUS PHARMACEUTICALS, INC.Inventors: Manjari Lal, Lynn Gold
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Patent number: 7223770Abstract: Tocopherol-modified therapeutic drug compounds; emulsion, microemulsion, and micelle formulations that include the compounds; methods for making the compounds and formulations; methods for administering the compounds and formulations; and methods for treating conditions using the compounds and formulations.Type: GrantFiled: October 29, 2004Date of Patent: May 29, 2007Assignee: Sonus Pharmaceuticals, Inc.Inventors: Yuehua Zhang, Lynn C. Gold
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Publication number: 20060252840Abstract: Fluorinated compounds and emulsions including the compounds. The compositions are useful as oxygen carriers and surfactants. In one embodiment, the fluorinated compound is pH sensitive. In one embodiment, the fluorinated compound is a vitamin E derivative. In one embodiment, the fluorinated compound is a vitamin K derivative.Type: ApplicationFiled: June 12, 2006Publication date: November 9, 2006Applicant: Sonus Pharmaceuticals, Inc.Inventors: Yuehua Zhang, Manjari Lal, Andrew Leo, Nagesh Palepu
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Patent number: 7129368Abstract: Platinum carboxylate anticancer compounds, pharmaceutical compositions that include the platinum carboxylate compounds, and methods for treating cellular proliferative diseases by administering the platinum carboxylate compounds.Type: GrantFiled: March 14, 2005Date of Patent: October 31, 2006Assignee: Sonus Pharmaceuticals, Inc.Inventor: Manjari Lal
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Publication number: 20060229359Abstract: Tocopherol-modified therapeutic drug compounds; emulsion, microemulsion, and micelle formulations that include the compounds; methods for making the compounds and formulations; methods for administering the compounds and formulations; and methods for treating conditions using the compounds and formulations.Type: ApplicationFiled: June 8, 2006Publication date: October 12, 2006Applicant: Sonus Pharmaceuticals, Inc.Inventors: Yuehua Zhang, Lynn Gold
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Patent number: 7091374Abstract: Fluorinated compounds and emulsions including the compounds. The compositions are useful as oxygen carriers and surfactants. In one embodiment, the fluorinated compound is pH sensitive. In one embodiment, the fluorinated compound is a vitamin E derivative. In one embodiment, the fluorinated compound is a vitamin K derivative.Type: GrantFiled: April 23, 2004Date of Patent: August 15, 2006Assignee: Sonus Pharmaceuticals, Inc.Inventors: Yuehua Zhang, Manjari Lal, Andrew Leo, Nagesh Palepu
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Patent number: 7038071Abstract: Platinum compounds, pharmaceutically acceptable salts, and prodrugs thereof. Compositions that include the platinum compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier. Methods for using the platinum compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.Type: GrantFiled: July 16, 2003Date of Patent: May 2, 2006Assignee: Sonus Pharmaceuticals, Inc.Inventor: Manjari Lal
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Patent number: 7030155Abstract: A method of making an emulsion of tocopherol incorporating a co-solvent and, stabilized by biocompatible surfactants, as a vehicle or carrier for therapeutic drugs, which is substantially ethanol free and which can be administered to animals or humans by various routes, is disclosed. Also included in the emulsion is PEGylated vitamin E. PEGylated ?-tocopherol includes polyethylene glycol subunits attached by a succinic acid diester at the ring hydroxyl of vitamin E and serves as a primary surfactant, stabilizer and a secondary solvent in emulsions of ?-tocopherol.Type: GrantFiled: May 17, 2002Date of Patent: April 18, 2006Assignee: Sonus Pharmaceuticals, Inc.Inventors: Karel J. Lambert, Panayiotis P. Constantinides, Alexander K. Tustian, Steven C. Quay
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Patent number: 6982282Abstract: An emulsion of ?-tocopherol, stabilized by biocompatible surfactants, as a vehicle or carrier for therapeutic drugs, which is substantially ethanol free and which can be administered to animals or humans via various routes is disclosed. Also included in the emulsion is PEGylated vitamin E. PEGylated ?-tocopherol includes polyethylene glycol subunits attached by a succinic acid diester at the ring hydroxyl of vitamin E and serves as a primary surfactant, stabilizer and a secondary solvent in emulsions of ?-tocopherol.Type: GrantFiled: May 17, 2002Date of Patent: January 3, 2006Assignee: Sonus Pharmaceuticals, Inc.Inventors: Karel J. Lambert, Panayiotis P. Constantinides, Steven C. Quay
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Patent number: 6864386Abstract: Fluorinated compounds and emulsions including the compounds. The compositions are useful as oxygen carriers and surfactants. In one embodiment, the fluorinated compound is pH sensitive. In one embodiment, the fluorinated compound is a vitamin E derivative. In one embodiment, the fluorinated compound is a vitamin K derivative.Type: GrantFiled: November 20, 2002Date of Patent: March 8, 2005Assignee: Sonus Pharmaceuticals, Inc.Inventors: Yuehua Zhang, Manjari Lal, Andrew Leo, Nagesh Palepu
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Patent number: 6858227Abstract: Vitamin E conjugates, methods for their preparation, and compositions that include the conjugates. The vitamin E conjugates include a tocopherol moiety covalently coupled through a linker moiety to either a pyroglutamate moiety, a pyrrolidinone moiety, or a gentisic acid moiety.Type: GrantFiled: November 20, 2002Date of Patent: February 22, 2005Assignee: Sonus Pharmaceuticals, Inc.Inventors: Manjari Lal, Yuehua Zhang, Nagesh Palepu
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Publication number: 20040202712Abstract: An emulsion of &agr;-tocopherol, stabilized by biocompatible surfactants, as a vehicle or carrier for therapeutic drugs, which is substantially ethanol free and which can be administered to animals or humans various routes is disclosed. Also included in the emulsion is PEGylated vitamin E PEGylated &agr;-tocopherol includes polyethylene glycol subunits attached by a succinic acid diester at the ring hydroxyl of vitamin E and serves as a primary surfactant, stabilizer and a secondary solvent in emulsions of &agr;-tocopherol.Type: ApplicationFiled: April 28, 2004Publication date: October 14, 2004Applicant: Sonus Pharmaceuticals, Inc.Inventors: Karel J. Lambert, Panayiotis P. Constantinides, Steven C. Quay