Abstract: A method for fluorescence microscopic imaging of an object may be performed by means of a fluorescence microscopic imaging system with light sheet illumination. The method includes generating a line of light and scanning the line of light to generate a light sheet and further includes performing a wavefront analysis on an analysis field of the object. The method further includes applying spatial filtering of the fluorescence light, where the spatial filtering includes scanning a filtering element with respect to a fluorescence image of the line of light formed in a filtering plane of the filtering element. The scanning of the filtering element may be synchronized with the scanning of the line of light such as to obtain a superposition, at each instant, of the filtering element and the fluorescence image of the line of light.

Abstract: The present invention relates to a pneumatic structure (10) comprising an inextensible body (12) defining at least a network of internal cavities (14), each cavity having a closed contour in at least one section of the cavity Each cavity being suitable for being pressurized so as to change the inextensible body from a rest configuration to at least one pressurized configuration, Inextensible body having, in each pressurized configuration, a macroscopic metric different from its macroscopic metric in the rest configuration, Each cavity being formed of at least two substantially rectilinear channels, each channel being fluidly connected to at least one of the other channels, the two said channels forming a heading change angle, Each cavity comprising at least one non-zero heading change angle, in particular at least three non-zero heading change angles.

Abstract: A method for analyzing a structure, including a measurement of a duration T, a mechanical S or acoustic energy Sac and/or a spatial extension ? of a sequence and/or a number of mechanical or acoustic events N or Nac in that sequence and/or of the mechanical A or acoustic Aac energies of the events of that sequence, and/or a measurement of a mechanical energy A or acoustic energy Aac of an event, and/or of a temporal frequency of mechanical events dN/dt or acoustic events dNac/dt, and/or of a dissipated mechanical energy rate dE/dt or of an acoustic energy rate dEac/dt at the time of that event, and according to the measurement of an event and/or the measurement of a sequence of events, a calculation by technical means of a data r representative of a state of health of the structure or of a time tc to failure of the structure.

Abstract: An apparatus for detecting one or more chemicals in a sample, the apparatus including: a scanning unit including a light source configured to scan the sample using a light beam having a linear-shaped illumination; a dispersive element configured to receive light from the sample and disperse the received light spatially in a parallel manner; a spatial light modulator configured to receive the dispersed light and select one or more wavelength bands of the dispersed light; and a detection unit including a one-dimensional array of detectors configured to receive the selected one or more wavelength bands and detect the one or more chemicals in the sample based on the selected one or more wavelength bands, each detector of the array of detectors being a photon detector having a detection surface having a dimension below 50 ?m, the dimension being in a direction of the linear-shaped illumination.

Abstract: The present disclosure relates to injectable or implantable compositions that are able to mimic different types of mineralized biological tissues and their uses in mineralized tissues repair and regeneration.

Abstract: The use of small organic molecules that genes involved in the calcium signal pathway for methods of treating or preventing myelin pathologies, such as, for example, multiple sclerosis and myelin pathologies associated with preterm birth. The methods involve administering to a subject in need thereof the small organic molecules or pharmaceutical compositions including the small organic molecules.

Abstract: Herbicides useful for controlling the proliferation of undesired plants. In particular, the use of at least one compound derived from chromene or chromane as a herbicidal agent, a phytotoxic composition including the at least one compound derived from chromene or chromane, as well as a method for treating and/or controlling plants using the at least one compound derived from chromene or chromane.

Abstract: The synthesis of chemical compounds having a dihydrobenzoxepine structure. In particular, a process for preparing chemical compounds having a 2,5-dihydro-benzoxepine structure by photochemical rearrangement from chemical compounds having a chromene structure. The process including a step of irradiating with ultraviolet radiation a solution in a solvent of the chemical compounds having a chromene structure.

Abstract: Method for estimating a movement of particles in a bone, including the following steps: obtaining data associated with ultrasonic waves emitted at a temporal frequency; obtaining ultrasonic wave phase velocities in the bone in various directions followed by the ultrasonic waves; obtaining videos showing the bone at a point, the videos issuing from ultrasonic waves; computing phase variations at the point between two images of the videos; and computing a particle movement at the point based on the temporal frequency, the data associated with the ultrasonic waves, the phase variations, and the phase velocities in the various directions.

Abstract: Disclosed is a device for the perfusion of an organ, including: a container of fluid, containing an organ bathed in the perfusion fluid; a first path including an inlet, an outlet and a pump; and a second path including an inlet, an outlet and a pump. The “arterial” outlet of the first path has a diameter smaller than a diameter of the “portal” outlet of the second path. The device additionally includes, between the pump and the outlet of the first path and/or between the pump and the outlet of the second path, an oxygenation unit arranged to oxygenate the fluid emerging from the “arterial” outlet of the first path more than the fluid emerging from the “portal” outlet of the second path. The device can include a communication path between the first path and the second path in order to oxygenate the second path. Use in liver transplantation.

Abstract: A pharmaceutical compositions includes GLP-1 and GLP-1 analogues inducing an anabolic stimulation of chondrocytes and a decreasing in chondrocyte catabolic including a decrease in cartilage matrix loss and cartilage degeneration for use in the treatment of cartilage disease. The composition induces cartilage regeneration and anabolic stimulation of chondrocytes, including chondrocyte proliferation and/or stem cell differentiation into chondrocytes.

Abstract: The disclosure is directed at providing molecular tools and methods for transgenes integration in the genome of host cells, in particular tools and method enabling a transposition-dependent expression of the transgene, thereby facilitating identification and selection of effectively transformed hosts.

Abstract: A technique for moving various objects such as cells and particles of hydrogel or a compressible material, suspended in a fluid, so as to form a layered structure akin to human organ tissue. A standing sound wave is propagated through the fluid so as to position the cells on a pressure node and the particles on a pressure antinode. As such, the cells have a positive acoustic contrast relative to the fluid, while the particles have a negative acoustic contrast relative to the fluid.

Abstract: Disclosed is a device including a detector producing a signal depending on variations of the pupil diameter of an eye of a subject, a display for presenting, to the subject, a light pattern subdivided into a plurality of regions, and an analyzer receiving the signal of the detector and analyzing the frequential content thereof. The display is controlled such that each region has a light intensity modulated at a respective modulation frequency, the modulation frequencies being different from one region to the next.

Abstract: Disclosed is a method for characterising an object, comprising: emission of ultrasonic waves that enter an object by passing through an external interface, then reflect off an internal interface, then exit the object by passing through the external interface again, the ultrasonic waves comprising first waves having a mode that varies according to a first variation during their propagation in the object, and second waves having a mode that varies according to a second variation during their propagation in the object; reception of echo signals comprising first signals representing echoes of the first waves, and second signals representing echoes of the second waves, construction of a plurality of images showing the object, the plurality of images being constructed from the echo signals, under the assumption that two characteristics of the object are equal to two candidate values, and comprising a first image constructed from the first signals, and a second constructed from the second signals; construction of a

Abstract: The present invention pertains to the field of nanoimprint lithography (NIL) processes and more specifically to a soft NIL process used for providing a sol-gel patterned layer on a substrate. Specifically, this process comprises a step of adjusting the solvent uptake of the sol-gel film to 10 to 50% vol., preferably between 15 and 40% vol., by varying the relative pressure of the solvent while a soft mould is applied onto the substrate coated with the sol-gel film.

Abstract: The present invention relates to antimicrobial peptides, variants and chemical analogues thereof; in particular, a peptide of 20 amino acids, named Michelicin, having the sequence RVCVRICRNGRCYRRCWNT, derived from a longer precursor with a BRICHOS domain from the marine worm Capitella. The peptide has several cysteines which form disulfide bridges and provide stability in salt conditions. Several derivatives and analogues were produced. The peptide and the derivatives show antimicrobial activity against a wide range of bacteria. The application also concerns nucleic acid sequences encoding these, pharmaceutical composition and to their use as a drug, preservative and disinfectant.

Abstract: Disclosed is chemical compounds C that are derivatives of norbixin and have tropism for the eye, and are intended to be used in the treatment of eye diseases in mammals, in particular in the context of altering the retinal pigment epithelium and more particularly in the context of age-related macular degeneration (AMD) and Stargardt's disease.

Abstract: The invention relates to a method for determining at least one property of an object, the method comprising a step of: a) obtaining first data relative to the object by an ultrasound imaging technique imaging the object at a frame rate superior to 300 Hz, characterized in that the method further comprises a step of: b) obtaining second data relative to the object by imaging the object with at least one of a X-ray and a ?-ray, and c) determining the at least one property of the object based on the first data and the second data.

Abstract: The invention relates to the use, as a herbicide, of at least one compound chosen from the compounds of general formula (I) and organic or inorganic salts thereof and isomers thereof. The invention also relates to a phytotoxic composition and to a method for controlling the development of and/or treating undesirable plants on the surface of a target zone.