Patents Assigned to SOUTH WEST THAMES INSTITUTE FOR RENAL RESEARCH
  • ANTISENSE COMPOUNDS TARGETING GENES ASSOCIATED WITH FIBRONECTIN
    Publication number: 20150291955
    Abstract: Provided are compounds comprising oligonucleotides complementary to a fibronectin transcript. Certain such compounds are useful for hybridizing to a fibronectin transcript, including but not limited to a fibronectin transcript in a cell. Such hybridization results in modulation of splicing of the fibronectin transcript. Such compounds are used to treat one or more symptoms associated with fibrosis. Such compounds are used to treat one or more symptoms associated with renal fibrosis.
    Type: Application
    Filed: June 3, 2013
    Publication date: October 15, 2015
    Applicants: SOUTH WEST THAMES INSTITUTE FOR RENAL RESEARCH, ISIS PHARMACEUTICALS, INC.
    Inventors: Susan M. Freier, Frank Rigo, Mark Dockrell, Felicia Heidibrecht