Abstract: An apparatus for enabling accurate retaining of a precise position, such as for reacquisition of a microscopic spot or feature having a size of 0.1 mm or less, on broad-area surfaces after non-in situ processing. The apparatus includes a sample and sample holder. The sample holder includes a base and three support posts. Two of the support posts interact with a cylindrical hole and a U-groove in the sample to establish location of one point on the sample and a line through the sample. Simultaneous contact of the third support post with the surface of the sample defines a plane through the sample. All points of the sample are therefore uniquely defined by the sample and sample holder. The position registration system of the current invention provides accuracy, as measured in x, y repeatability, of at least 140 ?m.

Abstract: A method and apparatus for the in vivo location and tracking of a radioactive seed source during and after brachytherapy treatment. The method comprises obtaining multiple views of the seed source in a living organism using: 1) a single PSPMT detector that is exposed through a multiplicity of pinholes thereby obtaining a plurality of images from a single angle; 2) a single PSPMT detector that may obtain an image through a single pinhole or a plurality of pinholes from a plurality of angles through movement of the detector; or 3) a plurality of PSPMT detectors that obtain a plurality of views from different angles simultaneously or virtually simultaneously. The plurality of images obtained from these various techniques, through angular displacement of the various acquired images, provide the information required to generate the three dimensional images needed to define the location of the radioactive seed source within the body of the living organism.

Abstract: A high voltage resistor comprising an array of a plurality of parallel electrically connected resistor elements each containing a resistive solution, attached at each end thereof to an end plate, and about the circumference of each of the end plates, a corona reduction ring. Each of the resistor elements comprises an insulating tube having an electrode inserted into each end thereof and held in position by one or more hose clamps about the outer periphery of the insulating tube. According to a preferred embodiment, the electrode is fabricated from stainless steel and has a mushroom shape at one end, that inserted into the tube, and a flat end for engagement with the end plates that provides connection of the resistor array and with a load.

Abstract: Stable THz radiation in the multi-watt range, upwards of 2 watts and even up to 100 watts, is produced through the acceleration of electrons in bunches less than about 500 femtoseconds in length as measured at full width and half maximum, at relativistic speeds (>˜40 MeV) and at a high repetition rate (>˜5 MHz) followed by transverse acceleration thereof by a magnetic field to produce the desired THz emission as synchrotron radiation.

Abstract: An improved method and apparatus increasing the accuracy and reducing the time required to machine materials, surface treat materials, and allow better control of defects such as particulates in pulsed laser deposition. The speed and quality of machining is improved by combining an ultrashort pulsed laser at high average power with a continuous wave laser. The ultrashort pulsed laser provides an initial ultrashort pulse, on the order of several hundred femtoseconds, to stimulate an electron avalanche in the target material. Coincident with the ultrashort pulse or shortly after it, a pulse from a continuous wave laser is applied to the target. The micromachining method and apparatus creates an initial ultrashort laser pulse to ignite the ablation followed by a longer laser pulse to sustain and enlarge on the ablation effect launched in the initial pulse. The pulse pairs are repeated at a high pulse repetition frequency and as often as desired to produce the desired micromachining effect.

Abstract: An image reconstruction method comprising accepting coincidence datat from either a data file or in real time from a pair of detector heads, culling event data that is outside a desired energy range, optionally saving the desired data for each detector position or for each pair of detector pixels on the two detector heads, and then reconstructing the image either by backprojection image reconstruction or by iterative image reconstruction. In the backprojection image reconstruction mode, rays are traced between centers of lines of response (LOR's), counts are then either allocated by nearest pixel interpolation or allocated by an overlap method and then corrected for geometric effects and attenuation and the data file updated.

Abstract: A Photo-Multiplier Tube (PMT) base for supplying long-term stable power, gain control and output amplification to a PMT. The present PMT base integrates the circuitry required for the dynode stages of the PMT with an amplifying circuit that amplifies the PMT output signals without disturbing the stable power that is required by each of the dynode stages. In operation the PMT base is electrically and mechanically connected to a PMT. The circuits for the dynode stages primarily provide gain control for each dynode stage in the PMT. The amplifying circuit in the PMT base is electrically connected to a dynode, the anode or both a dynode and the anode of the PMT, from which the PMT output signal is received. A PMT high voltage divider supplies the power to the circuitry required for the dynode stages and the amplifying circuit in the PMT base. The PMT base can be replaceable and can replace PMT bases that do not have an integrated amplifier for the PMT output signal.

Abstract: According to the present invention, there is provided a compact source of intense THz radiation comprising a short bunch, low energy particle beam source, an accelerator cavity and an electromagnetic wiggler. Application of state-of-the-art superconducting accelerating structures and beam recirculation allows such a THz radiation source to have a small footprint and high average intensity without the need of the larger equipment necessary to produce the large charge per bunch generally associated with the production of THz radiation. Consequently, low emittance electron beams can be used to produce emitted THz radiation of high average brilliance.

Abstract: In a camera or similar radiation sensitive device comprising a pixilated scintillation layer, a light guide and an array of position sensitive photomultiplier tubes, wherein there exists so-called dead space between adjacent photomultiplier tubes the improvement comprising a two part light guide comprising a first planar light spreading layer or portion having a first surface that addresses the scintillation layer and optically coupled thereto at a second surface that addresses the photomultiplier tubes, a second layer or portion comprising an array of trapezoidal light collectors defining gaps that span said dead space and are individually optically coupled to individual position sensitive photomultiplier tubes. According to a preferred embodiment, coupling of the trapezoidal light collectors to the position sensitive photomultiplier tubes is accomplished using an optical grease having about the same refractive index as the material of construction of the two part light guide.

Abstract: A system for providing high-resolution display for a matrix output device, such as a Photo-Multiplier Tube (PMT) matrix, that requires a substantially less number of amplifiers than prior readout systems. A resistor matrix is coupled directly to the outputs of a matrix output device. The outputs in each row in the matrix are combined and amplified with an amplifier that is at an end of each row. Similarly, the outputs in each column of the matrix are combined and amplified with an amplifier at an end of each column. The amplifiers at the end of each row and column also provide conversion of the signals from a current to a voltage. The converted and amplified signals are then processed, using a simple yet accurate algorithm such as center of gravity interpolation, to determine location and other information. The determined information may relate to detection of photons on the PMTs, for example, and is provided as an output signal from the processing circuitry.

Abstract: An introperative surgical probe incorporating both a fiber optic imaging system and multi-element beta/gamma radiation directional indicating system is described.

Abstract: A linear accelerator with improved efficiency is disclosed. The linear accelerator contains at least one lower beam energy recirculating linear accelerator which is focused along a constant focal length, and at least one higher beam energy recirculating linear accelerator which is focused along a constant focal length, and a full energy recirculating line which received the beam from the higher energy recirculating linear accelerator and reinjects it into the higher energy recirculating linear accelerator, thereby balancing the focusing profile to the beam energy. Better envelope control, focusing, and higher efficiency is observed in linacs according to the present invention.

Abstract: As an alternative to the use of a mechanical backing pump in the application of wide range turbomolecular pumps in ultra-high and extra high vacuum applications, palladium oxide is used to convert hydrogen present in the evacuation stream and related volumes to water with the water then being cryo-pumped to a low pressure of below about 1.e−3 Torr at 150° K. Cryo-pumping is achieved using a low cost Kleemenco cycle cryocooler, a somewhat more expensive thermoelectric cooler, a Venturi cooler or a similar device to achieve the required minimization of hydrogen partial pressure.

Abstract: A radial wedge flange clamp comprising a pair of flanges each comprising a plurality of peripheral flat wedge facets having flat wedge surfaces and opposed and mating flat surfaces attached to or otherwise engaged with two elements to be joined and including a series of generally U-shaped wedge clamps each having flat wedge interior surfaces and engaging one pair of said peripheral flat wedge facets. Each of said generally U-shaped wedge clamps has in its opposing extremities apertures for the tangential insertion of bolts to apply uniform radial force to said wedge clamps when assembled about said wedge segments.

Abstract: According to the present invention there is provided an injection modelocking Ti-sapphire laser system that produces a unidirectional laser oscillation through the application of a ring cavity laser that incorporates no intracavity devices to achieve unidirectional oscillation. An argon-ion or doubled Nd:YVO4 laser preferably serves as the pump laser and a gain-switched diode laser serves as the seed laser. A method for operating such a laser system to produce a unidirectional oscillating is also described.

Abstract: A system for improving the resolution of nuclear medicine gamma cameras. A pixellated crystal scintillator is optically connected to position sensitive photomultiplier tubes. Photons incident on the crystal scintillator travel a distance through the crystal that is directly proportional to the energy level of the photon before converting to photoelectrons. The system uses this depth of interaction information to classify the received photons according to their energy levels. Images may then be displayed using information from only those photons that are within the selected energy class.

Abstract: The invention described herein combines the structural digital X-ray image provided by conventional stereotactic core biopsy instruments with the additional functional metabolic gamma imaging obtained with a dedicated compact gamma imaging mini-camera. Before the procedure, the patient is injected with an appropriate radiopharmaceutical. The radiopharmaceutical uptake distribution within the breast under compression in a conventional examination table expressed by the intensity of gamma emissions is obtained for comparison (co-registration) with the digital mammography (X-ray) image. This dual modality mode of operation greatly increases the functionality of existing stereotactic biopsy devices by yielding a much smaller number of false positives than would be produced using X-ray images alone.

Abstract: An intra-operative beta particle probe is provided by placing a suitable photomultiplier tube (PMT), micro channel plate (MCP) or other electron multiplier device within a vacuum housing equipped with: 1) an appropriate beta particle permeable window; and 2) electron detection circuitry. Beta particles emitted in the immediate vicinity of the probe window will be received by the electron multiplier device and amplified to produce a detectable signal. Such a device is useful as a gamma insensitive, intra-operative, beta particle probe in surgeries where the patient has been injected with a beta emitting radiopharmaceutical. The method of use of such a device is also described, as is a position sensitive such device.

Abstract: A gamma camera comprising essentially and in order from the front outer or gamma ray impinging surface: 1) a collimator, 2) a scintillator layer, 3) a light guide, 4) an array of position sensitive, high resolution photomultiplier tubes, and 5) printed circuitry for receipt of the output of the photomultipliers. There is also described, a system wherein the output supplied by the high resolution, position sensitive photomultipiler tubes is communicated to: a) a digitizer and b) a computer where it is processed using advanced image processing techniques and a specific algorithm to calculate the center of gravity of any abnormality observed during imaging, and c) optional image display and telecommunications ports.

Abstract: The present invention describes a method for the detection of heat, incipient fire or combustion comprising the steps of: 1) incorporating a temperature-specific indicating agent which emits a specific detectable gas upon attainment of a predetermined temperature in an area where heat or incipient fire is to be detected, 2) providing a gas detector capable of detecting the specifically detectable gas emitted from the temperature-specific indicating agent; 3) detecting the specifically detectable gas; and 4) providing a warning or alarm when the specifically detectable gas reaches a predetermined concentration in the area. There is also disclosed a heat or incipient fire detection system comprising a temperature-specific indicating agent which emits a specific detectable gas upon attainment of a predetermined temperature and a detector for the specifically detectable gas.