Abstract: A portable isolation enclosure apparatus for safely removing material from the walls of a building structure while isolating the portion of the walls from which the material is being removed. The apparatus includes an booth with an open top, a plurality of side walls, and at least one open side disposed between two of the side walls. The apparatus is positioned against the wall such that an area of the wall is isolated from the ambient environment and is disposed in the open side of the booth such that a worker located inside the booth can access the area of the wall. A frame is adjustably attached to the booth so as to extend above the top of the booth a desired distance. A vacuum filter system is provided for drawing air from outside the booth into the interior of the booth, filtering the air along with any airborne contaminants, and then exhausting clean air to the environment.