Abstract: Certain embodiments are directed to a GMC1 co-solvent formulation. The GMC1 co-solvent formulation described herein can be used for the treatment of prostate cancer, benign prostatic hypertrophy, and other hormone-related conditions involving androgen, glucocorticoid, and progesterone receptors.
Type:
Application
Filed:
March 28, 2017
Publication date:
October 5, 2017
Applicants:
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, TEXAS SOUTHERN UNIVERSITY
Abstract: Provided herein are the metalloborane compounds, MOF-metalloborane compositions, and hydrogen storage system used for high density hydrogen storage. The compounds and compositions may have the structure M2B6H6 or MOF-M2B6H6-dicarboxylic acid. Particularly the transition metal M may be titanium or scandium and the MOF may be MOF5. The hydrogen storage systems hydrogen absorbed to the metalloborane compounds or to the MOF-metalloborane compositions. Methods of storing hydrogen are provided comprising flowing or passing hydrogen gas for absorptive contact with the metalloborane compounds or to the MOF-metalloborane compositions. Also provided is a method for calculating the hydrogen storage capacity of a metalloborane is provided in which random sampling of the thermodynamic states of a two-system model of hydrogen in the presence of a metal organic framework-metalloborane crystal structure is used to calculate probability of hydrogen absorption.
Type:
Application
Filed:
February 1, 2017
Publication date:
May 25, 2017
Applicant:
Texas Southern University
Inventors:
Christopher John Tymczak, Alireza Akbarzadeh, Daniel Vrinceanu
Abstract: The present invention relates to methods for treating an infectious disease in a subject in need thereof via administration of a therapeutically effective amount of compounds described herein. The methods may utilize particular compounds, for example, a quinoline, a hydrazone, a quinone, or a pyrimidine derivative thereof or a pharmaceutical salt thereof.
Type:
Application
Filed:
December 1, 2016
Publication date:
March 16, 2017
Applicant:
Texas Southern University
Inventors:
Omonike Arike Olaleye, Jun O. Liu, Sarah Finney John, Adaugo Chimzurum Isichei
Abstract: The present invention relates to methods for treating an infectious disease in a subject in need thereof via administration of a therapeutically effective amount of compounds described herein. The methods may utilize particular compounds, for example, a quinoline, a hydrazone, a quinone, or a pyrimidine derivative thereof or a pharmaceutical salt thereof.
Type:
Application
Filed:
November 29, 2016
Publication date:
March 16, 2017
Applicants:
Texas Southern University, The Board of Regents of the University of Texas System
Inventors:
Omonike Arike Olaleye, Sarah Finney John, Janice Endsley, Jun O. Liu, Rosa Maldonado
Abstract: The present invention relates to methods for treating an infectious disease in a subject in need thereof via administration of a therapeutically effective amount of compounds described herein. The methods may utilize particular compounds, for example, a quinoline, a hydrazone, a quinone, or a pyrimidine derivative thereof or a pharmaceutical salt thereof.
Type:
Application
Filed:
November 29, 2016
Publication date:
March 16, 2017
Applicants:
Texas Southern University, The Board of Regents of the University of Texas System
Inventors:
Omonike Arike Olaleye, Sarah Finney John, Janice Endsley, Jun O. Liu, Rosa Maldonado
Abstract: Provided herein is a pharmaceutical injectable formulation of itraconazole (10 mg/g) where the formulation comprises a solubilizer, a nonionic surfactant/emulsifier, a co-surfactant and a stabilizer. Further provided is a pharmaceutical formulation of itraconazole, said formulation comprising a solubilizer in a concentration of from about 20% to about 75%, a nonionic surfactant/emulsifier in a concentration of from about 20% to about 50%, a co-surfactant in a concentration from about 10% to about 45% and a stabilizer in a concentration of from about 1% to about 15%.
Type:
Grant
Filed:
September 22, 2011
Date of Patent:
October 18, 2016
Assignee:
Texas Southern University
Inventors:
Dong Liang, Lei Wu, Mathew Kizhakkekara Joseph, Jyothy Anie John
Abstract: Provided herein are systems for locating one or more hazardous material incidents, for example, a petrochemical incident, in a geographical area of interest. The system generally comprises electronic device with at least a processor, a memory and a display coupled to the processor and at least one network connection; and a user interactive tool coupled to the electronic device. Particularly, the interactive tool or interactive mapping tool comprises activatable widgets in an interface, databases accessible by the widgets and a mapping application and displayable interactive base map. Also provided is a method and utilizing the system to locate hazardous material incidents by activating the widgets, querying the databases and displaying incident data retrieved from the databases on the base map. Further provided is a non-transitory machine-readable storage device comprising processor-executable instructions to perform the method.
Abstract: Compositions, methods of making compositions, materials including compositions, crayons including compositions, paint including compositions, ink including compositions, waxes including compositions, polymers including compositions, vesicles including the compositions, methods of making each, and the like are disclosed.
Type:
Grant
Filed:
February 9, 2009
Date of Patent:
June 24, 2014
Assignees:
Georgia Southern University Research and Service Foundation, Inc., Lock Haven University of Pennsylvania
Inventors:
Weiyi Jia, Xiaojun Wang, George D. Jia, Linda Lewis, Laurel C. Yen
Abstract: A method comprising: dispersing carbon nanotubes in a solvent; and depositing the carbon nanotubes on a porous, conductive substrate; wherein the porous, conductive substrate is capable of functioning as a filter and a working electrode. The method of claim 1 further comprising: engaging the porous, conductive substrate with deposited carbon nanotubes in an electrochemical cell; and depositing at least one metallic structure on the surface of the carbon nanotubes from an electrolyte solution to form metallized carbon nanotubes. A composite comprising: metallized carbon nanotubes generated by the method of claim 2; wherein the at least one metallic structure comprises a conductive metal atom selected from the group consisting of platinum, gold nickel, copper, iron, chromium, zinc, and combinations thereof; and a matrix material selected from the group consisting of epoxies, thermosets, thermoplastics, elastomers, metals, metal matrix composites, ceramics and combinations thereof.
Type:
Grant
Filed:
December 26, 2007
Date of Patent:
April 29, 2014
Assignee:
Texas Southern University
Inventors:
Xin Wei, Yuanjian Deng, Renard L. Thomas, Bobby Wilson
Abstract: Provided herein is a pharmaceutical formulation of etravirine, said formulation comprising: etravirine; a dipolar aprotic solvent; a non-ionic water dispersible surfactant; and water. Further provided is a pharmaceutical formulation of etravirine, said formulation comprising: etravirine; a non-ionic water dispersible surfactant; and water.
Abstract: A method comprising: dispersing carbon nanotubes in a solvent; and depositing the carbon nanotubes on a porous, conductive substrate; wherein the porous, conductive substrate is capable of functioning as a filter and a working electrode. The method of claim 1 further comprising: engaging the porous, conductive substrate with deposited carbon nanotubes in an electrochemical cell; and depositing at least one metallic structure on the surface of the carbon nanotubes from an electrolyte solution to form metallized carbon nanotubes. A composite comprising: metallized carbon nanotubes generated by the method of claim 2; wherein the at least one metallic structure comprises a conductive metal atom selected from the group consisting of platinum, gold nickel, copper, iron, chromium, zinc, and combinations thereof; and a matrix material selected from the group consisting of epoxies, thermosets, thermoplastics, elastomers, metals, metal matrix composites, ceramics and combinations thereof.
Type:
Application
Filed:
December 26, 2007
Publication date:
June 10, 2010
Applicant:
Texas Southern University
Inventors:
Xin Wei, Yuanjian Deng, Renard L. Thomas, Bobby Wilson
Abstract: Substrates containing a copolymer of sequentially alternating lysine and alanine residues are provided. The use of those substrates for promoting neuron survival and axon growth are also provided.