Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit cystathionine-?-lyase (CSE). Also described herein are methods for using such CSE inhibitors, alone or in combination with other compounds, for treating diseases or conditions that would benefit from CSE inhibition.
Type:
Grant
Filed:
August 9, 2017
Date of Patent:
March 12, 2019
Assignee:
SOVA PHARMACEUTICALS, INC.
Inventors:
Sergio G. Durón, Justin Chapman, Simon G. Sydserff, Srinivas G. Rao, Gregory Stein
Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit cystathionine-?-lyase (CSE). Also described herein are methods for using such CSE inhibitors, alone or in combination with other compounds, for treating diseases or conditions that would benefit from CSE inhibition.
Type:
Grant
Filed:
July 23, 2013
Date of Patent:
September 26, 2017
Assignee:
SOVA PHARMACEUTICALS, INC.
Inventors:
Sergio G. Durón, Justin Chapman, Simon G. Sydserff, Srinivas G. Rao, Gregory Stein
Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit cystathionine-?-lyase (CSE). Also described herein are methods for using such CSE inhibitors, alone or in combination with other compounds, for treating diseases or conditions that would benefit from CSE inhibition.
Type:
Grant
Filed:
July 23, 2013
Date of Patent:
August 8, 2017
Assignee:
SOVA PHARMACEUTICALS, INC.
Inventors:
Sergio G. Durón, Justin Chapman, Simon G. Sydserff, Srinivas G. Rao, Gregory Stein, Warren Wade
Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds which inhibit cystathionine-?-lyase (CSE). Also described herein are methods for using such CSE inhibitors, alone or in combination with other compounds, for treating diseases or conditions that would benefit from CSE inhibition.
Type:
Application
Filed:
July 23, 2013
Publication date:
June 25, 2015
Applicant:
SOVA PHARMACEUTICALS, INC.
Inventors:
Sergio G. Durón, Justin Chapman, Simon G. Sydserff, Srinivas G. Rao, Gregory Stein
Abstract: Described herein are methods for modulation of the activity of the carotid body that afford therapeutic benefit for sleep-related breathing disorders and related conditions.
Type:
Application
Filed:
April 11, 2011
Publication date:
May 23, 2013
Applicants:
JOHNS HOPKINS UNIVERSITY, SOVA PHARMACEUTICALS, INC., THE UNIVERSITY OF CHICAGO
Inventors:
Solomon H. Snyder, Moataz M. Gadalla, Nanduri R. Prabhakar, Gregory Stein, Gary Pace