Abstract: We disclose a method of obtaining a polyepitopic protein, a DNA vector for the embodiment of the method as well as polyepitopic proteins fused with macromolecular carriers. The proteins obtained according to the present invention are in a number of uses, in particular when used in the production of improved vaccines.

Abstract: An actuator device which includes a fixed support structure, an actuation member movable, a biasing member tending to maintain the actuation member in a rest position, a shape-memory wire connected to the structure and to the actuation member, and an electric circuit for supplying an electric current to the shape-memory wire. The circuit includes a pair of terminals. One end of the shape-memory wire is connected to a first terminal. The circuit includes further an electric switch, including a first conducting member electrically connected with the second terminal, and a second conducting member carried by the actuation member and electrically connected with the other end of the shape-memory wire. The switch is closed when the actuation member is in the rest position, and remains closed until when the actuation member reaches a working position, and opens when the actuation member passes beyond the working position.

Abstract: The present invention relates to a method for selection or screening of hDIS3 PIN domain inhibitors, yeast strain and cell line used in such methods It also relates to new therapeutic agents selected hDIS3 PIN domain inhibitors and uses thereof in the treatment of cancers having mutations inhDIS3 RNB domain, especially multiple myeloma. The invention also relates to composition comprising new therapeutic agent hDIS3 PIN domain inhibitor and method for inducing synthetic lethality in a cancer cell.

Abstract: The invention relates to an electric circuit of a generator of oscillations, comprising an enhancement-mode field transistor T1, inductance L1 and resistance R1 connected to the source or the drain of the transistor T1, characterized in that the inductance L1 is connected directly between the gate and the drain of the transistor T1 or to an electric circuit of a generator of oscillations, comprising an depletion-mode field transistor T1, inductance L1 and resistance R1 connected with its one end to the source of the transistor T1, characterized in that the inductance L1 is connected directly between the gate of the transistor T1 and the other end of the resistance R1.

Abstract: The subject of the invention is a motor, specifically an automobile windscreen wiper mechanism, containing a casing (1,2) which defines an internal space, characterized in that the internal space of the motor is partially limited by a reversibly deforming element (5), preferably an elastic membrane (5), enabling the volume of the internal space to change under the influence of pressure exerted on the casing (1,2).

Abstract: A wind turbine includes a turbine housing, a turbine wheel system housed in the turbine housing, and a wind power converting system for converting kinetic energy generated by the turbine wheel system into electrical energy. The turbine wheel system includes a turbine rotor being driven to rotate circumferentially around an interior of the turbine housing, and a rail frame guiding a rotational movement of a turbine rotor. The wind turbine not only allows airflow to move across and through the turbine wheel system but also allows airflow to be directed and exhausted to maximize and control energy generation. The wind turbine is able to efficiently convert wind power to electrical power via a turbine wheel system which allows for the load generated to be distributed across the circumference of the turbine wheel system instead of localized in the center as the traditional wind turbine.

Abstract: An automation system is disclosed in which a system controller has access to the signals transmitted by each sensor device that is relevant to the environment being controlled. Each sensor device monitors a particular physical condition, senses changes in the condition being monitored, and reports states of the condition, which is made available to the system controller. Meanwhile, the system controller memorizes and maintains the states of various processing events, such as when a sensor device reported a particular state of the condition that the sensor monitors. By considering the information reported by the various and multiple sensor devices, as well as by accounting for the memorized states corresponding to the various events, the system controller is able to generate and continually update a representation of the state of the controlled environment. Having such context awareness enables the design and implementation of sophisticated reasoning logic and conditional logic.

Abstract: The reclosing mechanism for containers, particularly beverage containers, has the latch (3) fitted slidingly in the opening (5). Formed on the top side of the latch (3) there is an attachment (14) shorter than the opening (5) and narrower than the latch (3), where the attachment (14) is fitted with a pull tab (4) longer than the attachment (14) and fixed to the attachment (14) with a hinge (6) and a connector (7) which serves as the seal before the first opening. Formed on the opposite longitudinal sides of the attachment (14) there are catches (8) fitted slidingly on the guides (13) formed on the longer side walls of the opening (5). On the top surface of the element in which the opening (5) is made there are protrusions (10) formed on the side of the pull tab (4) front, on which the pull tab (4) rests and blocks the sliding of the latch (3) in the closed position.

Abstract: A seal comprises a lid that is rotary-mounted to a filter container base and has a body with at least two stub pipes and an internal part attached to the body in which are formed circulation ducts positioned as an extension of the stub pipes in opened position, and at least one bypass duct connecting the stub pipes in closed position. The internal part is attached to the body using a rotary bayonet mount by rotating to closed position in which the stub pipes are connected by the bypass duct, and the body together with the attached internal part are attached to the base using a rotate-and-lock bayonet mount. In closed position the internal part is attached to the base in a stationary manner using a longitudinal head joint formed on the joined elements, and the changing to opened position occurs by rotating the body in the rotate-and-lock bayonet mount.

Abstract: An assembly according to the invention includes two pairs of relays, such as SSR semiconductor relays. The relays of each pair operate with the opposite direct current potentials. Direct current with the voltage of 220 V to 400 V as well as control lines are connected to the clamps of the controlled relays. The operation of the relays is controlled by means of a controller, such as a PLC programmable controller. The relays are connected to the first electrode clamp, and the other relays to the second electrode clamp. The assembly operates in such a way that the PLC controller activates the relays from the line, which simultaneously activate the flow of the direct current with the voltage of 220 V to 400 V and mutually opposite polarity. As a result of this, a difference of potentials appears on the electrode clamps.

Abstract: The object of the application is a filling hopper for a filling apparatus for multi-segment trays in the tobacco industry with a receiving region for rod like articles in the form of a mass flow and a storing region for rod like articles comprising side walls (8, 9) and a bottom wall (10), whereas the storing region has double partition walls (16) alternately forming a plurality of parallel cavities (15) and slots (14), where the partition walls (16) extend in principle along the entire height of the storing region. The partition walls (16) are connected with each other by means of a carrying framework so that at least from one side free access to the articles inside the cavities (15) is maintained. The carrying framework comprises at least one fastening area (19).

Abstract: An automatic applicator for liquid pharmaceutical preparations, particularly for multiple injection application of set doses of a medicine from an exchangeable container is provided. The automatic applicator includes a body housing connected to a housing of an exchangeable container with a medicine having a plunger, the said plunger being displaced only linearly by an integrated driving unit, suitable for immobilizing, driving, leading linearly and blocking rotation of the plunger, driven via a double action clutch, by a tensioning spring situated in the body housing, the spring tensioned by a rotary hand-dose-setting ring via the double action clutch, wherein the driving unit is activated by a trigger unit and a dose is indicated by an indicating arrangement. The automatic applicator further includes at least one block key placed in an upper part of a ratchet barrel, collaborating with at least one key placed in an internal part of the body housing.

Abstract: The corridor for transporting abrasive in an impact chamber is laterally limited by longitudinal sections resting on a foundation slab. The corridor has a traction system for moving an axle set along a transport track, the traction system being provided with a substantially horizontal loop including loop return wheels and a loop connector having two bands moving in opposite directions. Each band of the loop connector is placed in an individually assigned guiding slot, arranged on top of the longitudinal section. There is a method for moving an axle set in an impact chamber having a corridor for transporting abrasive, wherein each band of the loop connector is carried in the immediate vicinity of the side edge of the corridor for transporting abrasive, on top of the longitudinal section.

Abstract: A method for hydrothermal liquefaction of biomass, wherein the biomass supplied by pumps from a tank is provided to a reactor, in which the biomass is heated to obtain reactor products in the form of volatile, liquid and solid fractions, which are separated in a separator. The biomass supplied from the tank is pressurized in pumps, after which it is preliminarily heated in a heat exchanger. The preheated biomass is reheated in the reactor using microwave radiation. The temperature of the biomass inside the reactor is measured using temperature sensors and a controller, and based on the measurements of the temperature sensors and reflectometers, the power of radiation is adjusted to retain the biomass inside the reactor at the temperature of 374° C. to 400° C.

Abstract: The subject matter of this invention is a telescopic actuator with tubular cylinders which at the same time function as pistons, used to move/shift/translocate pieces of devices especially while emergency opening damaged movable elements/components. It has a bushing body (1) connected with a head (5) attached to its free end and the head has a control segment (10) and the systems feeding the actuator with pressure agent/factor, created in the form of at least one gas generator (9); and by the fact that the bushing/sleeve body (1), the first cylindrical piston (2) and another cylindrical piston (3) have at least one ring groove situated on the surface mating with another tubular element near the head faces of those tubular elements.

Abstract: A storage device, especially for storing items such as parcels or courier packages, including a housing 1, shelves 7 with products 5, an automatic inserter/extractor 3, a drop-off/pick-up window 6, and an electronic control panel 8, characterized in that inside the housing 1 three separate zones are located: a low-temperature zone LT, a medium-temperature zone NT, and an ambient-temperature zone PT, separated from each other by insulating panels 2, between which the automatic inserter/extractor 3 moves, whereas the access of the automatic inserter/extractor 3 to the low-temperature zone LT and the medium-temperature zone NT, with temperatures different than the ambient temperature, is obtained through thermally insulating movable partitions 4.

Abstract: The invention provides a process for the preparation of xanthohumol, wherein a xanthohumol-containing extract is mixed with water, a transition metal salt solution is added to the obtained mixture, and then the obtained xanthohumol precipitate is collected and dried to obtain xanthohumol of the purity higher than 90%.

Abstract: The object of the invention is a unit fixing insulation to the wall intended both for styrofoam insulation as well as for mineral wool insulation. A unit fixing insulation to a wall, according to the invention, is formed with the locating sleeve on which a pressing sleeve is slidably mounted, constituting an integral unit with a circular pressing plate provided with slitting teeth arranged along the circumference of a circular plate and the locating sleeve is ended at one end with an expansion zone and at the other end with a circular plate, whereas the locating sleeve houses an expansion element, preferably in the form of a screw. A unit characterised in that the expansion element has a head embedded permanently in the sleeve with an outer thread and a polygonal hole is provided within the sleeve, whereas a pressing plate is ended with a circular flange which houses the insulating cap, while the teeth of the pressing plate have side and front sharp edges.

Abstract: The object of the invention is a unit fixing insulation to the wall intended both for styrofoam insulation as well as for mineral wool insulation. A unit fixing insulation to a wall, according to the invention, is formed with the locating sleeve which is ended at one end with an expansion zone, and with a circular plate at the other end, whereas the locating sleeve houses an expansion element, preferably in the form of a screw. A unit characterized in that the expansion element has a head embedded permanently in the sleeve with an outer thread and a polygonal hole is provided within the sleeve, and the locating sleeve has a diameter with gradation, wherein a larger diameter is from the inlet side.

Abstract: The invention relates to a sports racquet having a head having a string bed is attached to two throat beams that extend continuously downward to a shaft having a handle. Each throat beam contains a bending zone in which the width of the throat beam parallel to the string bed and the width of the same throat beam perpendicular to the string bed gradually changes in equal, but opposite, dimensions such that the circumference of the throat beam remains substantially constant through at least the length of the bending zone or the length of the entire throat beam. Where the width of the throat beam parallel to the string bed is the widest and the width of the throat beam perpendicular to the string beg is the narrowest defines the flexible cross-section or flex point of the bending zone.