Abstract: The main object here is the use of omega-3 polyunsaturated fatty acids (as ethyl esters, hereinafter called “n-3 PUFA”) as a medicament, either alone or in combination with other therapeutic agents, for reducing mortality for a cardiovascular cause, in particular arrhythmia or for reducing hospitalization for any cause, in particular a cardiovascular cause and for the daily administration to patients with symptomatic heart failure (HF) for more than 3.5 years.

Abstract: The main object here is the use of omega-3 polyunsaturated fatty acids (as ethyl esters, hereinafter called “n-3 PUFA”) as a medicament, either alone or in combination with other therapeutic agents, for reducing mortality for a cardiovascular cause, in particular arrhythmia or for reducing hospitalization for any cause, in particular a cardiovascular cause and for the daily administration to patients with symptomatic heart failure (HF) for more than 3.5 years.

Abstract: The present invention is directed towards a series of secondary and tertiary amide derivatives of Partricin A & Partricin B attached at the C-18 carboxyl group. The compounds can be used in the treatment of hypercholesteremia and hyperlipemia conditions, of steroidal imbalances, and as antifungal and antiprotozoan agents.

Abstract: Peptide derivatives and their salts with pharmaceutically acceptable acids or bases, having the general formula (I), ##STR1## wherein R=--H, C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 acyl, alkoxycarbonyl with C.sub.1 -C.sub.4 alkyl;R.sub.1 =--H, C.sub.1 -C.sub.3 alkyl;R.sub.2 =--H, --OH, --OR'.sub.2, wherein R'.sub.2 =C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 acyl, benzyl;R.sub.3 =--H, --CH.sub.3 ;n=1,2R.sub.4 =--H, --COOH, --CONH.sub.2, --COOR'.sub.4, wherein R'.sub.4 =C.sub.1 -C.sub.3 alkyl, benzyl;R.sub.5 =--H, 4--OH, 3,4--OH, --OR'.sub.5 wherein R'.sub.5 =C.sub.1 -3 alkyl, C.sub.1 -C.sub.3 acyl, benzyl;R.sub.6 =--OH, --NH.sub.2, --OR'.sub.6 wherein R'.sub.6 =C.sub.1 -C.sub.3 alkyl, benzyl; endowed with analgesic, antiviral, immuno-modulating pharmacological properties, and the pharmaceutical forms containing them as active ingredients.

Abstract: Process for the decontamination of vegetable foods from Listeria-sp. which consists in adding solutions of lysozyme, non-toxic and physiologically compatible salts thereof, to said foods, with or without adjuvant substances, at concentrations suitable for affording decontamination.

Abstract: A process for the preparation of foods of animal origin wherein efficacious quantities of lysozyme or its non-toxic salts--and optionally of synergic agents or adjuvant--are added to said foods to the purpose of obtaining foods free of Listeria bacteria.

Abstract: A peptide made up of at least 3 amino acids comprised in sequential form in the following structure: ##STR1## where Y may be absent or represent a glycine residue, where the amino acids ##STR2## represent the sequences between positions 39-45 and 46-53 of hen egg-white lysozyme.

Abstract: Compounds of the following general structure (I) ##STR1## where R.sub.1 stands for an acyl radical of the following structure (II) ##STR2## where p1 X.sup.- is a halogen atom and R.sub.4 is a C.sub.1 -C.sub.4 acyl radical or a hydrogen atomR.sub.2 stands for an R.sub.1 radical as defined above or for a hydrogen atomR.sub.3 stands for a substituted hydroxymethyl CH.sub.2 OR.sub.1 group, where R.sub.1 has the same value as defined above, or for a carboxyl group.

Abstract: The invention relates to new rifamycins derivatives endowed with antibiotic activity and process for their preparation.

Abstract: A new benzothiazine derivative, that is N-(2-pyridyl)-2-methyl-4-cinnamoyloxy-2H-1,2-benzothiazine-3-carboxamido 1,1-dioxide has been prepared. Owing to its peculiar ester structure, obtained by condensation with cinnamic acid, the new product is endowed with so outstanding pharmacological and toxicological activities, particularly with reference to its tolerableness, to make it a therapeutically valuable anti-inflammatory drug.

Abstract: The present invention provides a method of relieving pain and of treating inflammatory conditions in warm-blooded animals, including humans, which comprises administering to a warm-blooded animal suffering from an inflammatory condition a phenyl-alkanoic acid salt of the general formula: ##STR1## wherein R.sub.1 is a hydrogen atom or a methyl radical, R.sub.2 is a halogen atom or an alkyl radical containing up to 5 carbon atoms, which may be straight-chained or branched, for example an isobutyl radical, or is a cyclohexyl radical or is a phenoxy or benzoyl radical, which may be substituted by one or two halogen atoms, R.sub.3 is a hydrogen atom or an allyloxy radical or R.sub.2 and R.sub.

Abstract: The present invention is concerned with a method for the treatment of benign prostatic hypertrophy in male humans, comprising administering an effective amount of a compound selected from the group consisting of partricin, C.sub.1 -C.sub.6 alkyl ester of partricin and C.sub.1 -C.sub.6 alkyl ester of N-mono- and N,N-disubstituted partricin, the N-substituents being C.sub.1 -C.sub.6 alkyl or carboxylic acyl, to a human male suffering from benign prostatic hypertrophy.

Abstract: The present invention provides a method of treating domestic animals which are infected or endangered by micro-organisms, as well as solid and liquid nutriments for domestic animals comprising lysozyme and/or at least one non-toxic salt thereof.The present invention also provides, as new compounds, lysozyme phosphate, glycerophosphate, lactate, gluconate and hexametaphosphate, as well as a process for the preparation thereof.

Abstract: The present invention provides a water-soluble pharmaceutical complex, comprising the antibiotic partricin and/or an alkyl ester thereof and sodium desoxycholate and/or sodium dehydrocholate.

Abstract: The present invention is concerned with a new and improved process for the recovery of the polyene antibiotic partricin, wherein a surface-active agent is added to a fermented liquor containing partricin in an amount sufficient to bring the partricin into solution, whereafter insoluble material is removed and the partricin is recovered from the aqueous solution.

Abstract: The present invention provides a water-soluble pharmaceutical composition, comprising partricin and/or partricin methyl ester in admixture with at least one anionic and/or cationic surfactant.

Abstract: The present invention provides new esters of partricin and of N-substituted derivatives of partricin.

Abstract: The present invention provides new salts and complexes of lysozyme and of basic derivatives of lysozyme with bile acids, processes for the preparation thereof and the pharmaceutical use thereof.

Abstract: The present invention provides a process for the preparation of alkyl esters of polyene antibiotics, wherein a polyene antibiotic is reacted with a diazoalkane in the presence of a basic substance.The present invention also provides, as new materials, alkyl esters of polyene antibiotics in which the alkyl radical of the ester grouping contains 2 or more carbon atoms.