Patents Assigned to Spangler Scientific LLC
  • Patent number: 11839497
    Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: December 12, 2023
    Assignee: Spangler Scientific LLC
    Inventor: Gregory J. Spangler
  • Publication number: 20220386966
    Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk determination is accomplished and may have a sensitivity and specificity of greater than 95%, by generating linear and nonlinear mathematical digital ECG-constructed models from digital ECG-type data of an individual's digital ECG, determining stability/instability of digital ECG-constructed control model systems corresponding to the digital ECG-constructed models by a plurality of techniques and transforming stability/instability values obtained by the determining stability/instability into a quantitative value reflecting an individual's risk for SCD.
    Type: Application
    Filed: May 12, 2022
    Publication date: December 8, 2022
    Applicant: SPANGLER SCIENTIFIC LLC
    Inventor: Gregory J. Spangler
  • Patent number: 11331049
    Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk determination is accomplished and may have a sensitivity and specificity of greater than 95%, by generating linear and nonlinear mathematical digital ECG-constructed models from digital ECG-type data of an individual's digital ECG, determining stability/instability of digital ECG-constructed control model systems corresponding to the digital ECG-constructed models by a plurality of techniques and transforming stability/instability values obtained by the determining stability/instability into a quantitative value reflecting an individual's risk for SCD.
    Type: Grant
    Filed: August 24, 2020
    Date of Patent: May 17, 2022
    Assignee: Spangler Scientific LLC
    Inventor: Gregory J. Spangler
  • Publication number: 20210378576
    Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
    Type: Application
    Filed: June 17, 2021
    Publication date: December 9, 2021
    Applicant: Spangler Scientific LLC
    Inventor: Gregory J. Spangler
  • Patent number: 11045135
    Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: June 29, 2021
    Assignee: Spangler Scientific LLC
    Inventor: Gregory J. Spangler
  • Publication number: 20210128072
    Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk determination is accomplished and may have a sensitivity and specificity of greater than 95%, by generating linear and nonlinear mathematical digital ECG-constructed models from digital ECG-type data of an individual's digital ECG, determining stability/instability of digital ECG-constructed control model systems corresponding to the digital ECG-constructed models by a plurality of techniques and transforming stability/instability values obtained by the determining stability/instability into a quantitative value reflecting an individual's risk for SCD.
    Type: Application
    Filed: August 24, 2020
    Publication date: May 6, 2021
    Applicant: SPANGLER SCIENTIFIC LLC
    Inventor: Gregory J. SPANGLER
  • Publication number: 20190150769
    Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
    Type: Application
    Filed: January 29, 2019
    Publication date: May 23, 2019
    Applicant: SPANGLER SCIENTIFIC LLC
    Inventor: Gregory J. SPANGLER
  • Patent number: 10226196
    Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: March 12, 2019
    Assignee: Spangler Scientific LLC
    Inventor: Gregory J. Spangler
  • Publication number: 20180249965
    Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk determination is accomplished and may have a sensitivity and specificity of greater than 95%, by generating linear and nonlinear mathematical digital ECG-constructed models from digital ECG-type data of an individual's digital ECG, determining stability/instability of digital ECG-constructed control model systems corresponding to the digital ECG-constructed models by a plurality of techniques and transforming stability/instability values obtained by the determining stability/instability into a quantitative value reflecting an individual's risk for SCD.
    Type: Application
    Filed: September 13, 2016
    Publication date: September 6, 2018
    Applicant: SPANGLER SCIENTIFIC LLC
    Inventor: Gregory J. Spangler, M.D., Ph.D.
  • Publication number: 20170367604
    Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
    Type: Application
    Filed: September 1, 2017
    Publication date: December 28, 2017
    Applicant: SPANGLER SCIENTIFIC LLC
    Inventor: Gregory J. Spangler
  • Patent number: 9775535
    Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: October 3, 2017
    Assignee: Spangler Scientific LLC
    Inventor: Gregory J. Spangler
  • Publication number: 20160270682
    Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
    Type: Application
    Filed: November 7, 2014
    Publication date: September 22, 2016
    Applicant: Spangler Scientific LLC
    Inventor: Gregory J. SPANGLER