Patents Assigned to Spangler Scientific LLC
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Publication number: 20240245362Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.Type: ApplicationFiled: November 28, 2023Publication date: July 25, 2024Applicant: SPANGLER SCIENTIFIC LLCInventor: Gregory J. Spangler
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Patent number: 11839497Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.Type: GrantFiled: June 17, 2021Date of Patent: December 12, 2023Assignee: Spangler Scientific LLCInventor: Gregory J. Spangler
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Publication number: 20220386966Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk determination is accomplished and may have a sensitivity and specificity of greater than 95%, by generating linear and nonlinear mathematical digital ECG-constructed models from digital ECG-type data of an individual's digital ECG, determining stability/instability of digital ECG-constructed control model systems corresponding to the digital ECG-constructed models by a plurality of techniques and transforming stability/instability values obtained by the determining stability/instability into a quantitative value reflecting an individual's risk for SCD.Type: ApplicationFiled: May 12, 2022Publication date: December 8, 2022Applicant: SPANGLER SCIENTIFIC LLCInventor: Gregory J. Spangler
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Patent number: 11331049Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk determination is accomplished and may have a sensitivity and specificity of greater than 95%, by generating linear and nonlinear mathematical digital ECG-constructed models from digital ECG-type data of an individual's digital ECG, determining stability/instability of digital ECG-constructed control model systems corresponding to the digital ECG-constructed models by a plurality of techniques and transforming stability/instability values obtained by the determining stability/instability into a quantitative value reflecting an individual's risk for SCD.Type: GrantFiled: August 24, 2020Date of Patent: May 17, 2022Assignee: Spangler Scientific LLCInventor: Gregory J. Spangler
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Publication number: 20210378576Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.Type: ApplicationFiled: June 17, 2021Publication date: December 9, 2021Applicant: Spangler Scientific LLCInventor: Gregory J. Spangler
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Patent number: 11045135Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.Type: GrantFiled: January 29, 2019Date of Patent: June 29, 2021Assignee: Spangler Scientific LLCInventor: Gregory J. Spangler
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Publication number: 20210128072Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk determination is accomplished and may have a sensitivity and specificity of greater than 95%, by generating linear and nonlinear mathematical digital ECG-constructed models from digital ECG-type data of an individual's digital ECG, determining stability/instability of digital ECG-constructed control model systems corresponding to the digital ECG-constructed models by a plurality of techniques and transforming stability/instability values obtained by the determining stability/instability into a quantitative value reflecting an individual's risk for SCD.Type: ApplicationFiled: August 24, 2020Publication date: May 6, 2021Applicant: SPANGLER SCIENTIFIC LLCInventor: Gregory J. SPANGLER
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Publication number: 20190150769Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.Type: ApplicationFiled: January 29, 2019Publication date: May 23, 2019Applicant: SPANGLER SCIENTIFIC LLCInventor: Gregory J. SPANGLER
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Patent number: 10226196Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.Type: GrantFiled: September 1, 2017Date of Patent: March 12, 2019Assignee: Spangler Scientific LLCInventor: Gregory J. Spangler
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Publication number: 20180249965Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk determination is accomplished and may have a sensitivity and specificity of greater than 95%, by generating linear and nonlinear mathematical digital ECG-constructed models from digital ECG-type data of an individual's digital ECG, determining stability/instability of digital ECG-constructed control model systems corresponding to the digital ECG-constructed models by a plurality of techniques and transforming stability/instability values obtained by the determining stability/instability into a quantitative value reflecting an individual's risk for SCD.Type: ApplicationFiled: September 13, 2016Publication date: September 6, 2018Applicant: SPANGLER SCIENTIFIC LLCInventor: Gregory J. Spangler, M.D., Ph.D.
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Publication number: 20170367604Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.Type: ApplicationFiled: September 1, 2017Publication date: December 28, 2017Applicant: SPANGLER SCIENTIFIC LLCInventor: Gregory J. Spangler
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Patent number: 9775535Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.Type: GrantFiled: November 7, 2014Date of Patent: October 3, 2017Assignee: Spangler Scientific LLCInventor: Gregory J. Spangler
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Publication number: 20160270682Abstract: A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.Type: ApplicationFiled: November 7, 2014Publication date: September 22, 2016Applicant: Spangler Scientific LLCInventor: Gregory J. SPANGLER