Patents Assigned to Specialty Laboratories, Inc.
  • Method of screening for silicone-specific hypersensitivity
    Patent number: 5747270
    Abstract: An in vitro method for diagnosing hypersensitivity to silicon(e) antigen in subjects not previously exposed to silicon(e). The method involves obtaining a subset of lymphocytes from non-sensitized subjects and contacting the lymphocytes with silicon(e) for a sufficient period of time to cause sensitizing and proliferative responses.
    Type: Grant
    Filed: April 6, 1995
    Date of Patent: May 5, 1998
    Assignee: Specialty Laboratories, Inc.
    Inventor: Emmanuel Ojo-Amaize
  • Assay for glycosylation deficiency disorders
    Patent number: 5432059
    Abstract: A method is provided for detecting carbohydrate-deficient glycoproteins in samples taken from subjects with metabolic disorders, such as alcohol abuse and subjects who display a syndrome of carrying abnormal levels of carbohydrate deficient glycoproteins. The method involves steps of reglycosylating with a fluorescent-conjugate deglycosylated glycoproteins in a sample of body fluid from a subject. A further step involves fluorometric detection of fluoresceinylated carbohydrates incorporated into truncated serum glycoproteins.
    Type: Grant
    Filed: April 1, 1994
    Date of Patent: July 11, 1995
    Assignee: Specialty Laboratories, Inc.
    Inventors: Pamela Bean, Jeff W. Terryberry
  • Rapid purification of DNA
    Patent number: 5234824
    Abstract: The present invention provides a method for rapidly obtaining substantially pure DNA from a biological sample containing cells. The method involves gently lysing the membranes of the cells to yield a lysate containing genomic DNA in a high molecular weight form. The lysate is moved through a porous filter to selectively trap the high molecular weight DNA on the filter. The DNA is released from the filter using an aqueous solution to form a solution containing substantially purified DNA, from which the DNA may analyzed or recovered.
    Type: Grant
    Filed: June 2, 1992
    Date of Patent: August 10, 1993
    Assignee: Specialty Laboratories, Inc.
    Inventor: Kary B. Mullis
  • Rapid purification of DNA
    Patent number: 5187083
    Abstract: The present invention provides a method for rapidly obtaining substantially pure DNA from a biological sample containing cells. The method involves gently lysing the membranes of the cells to yield a lysate containing genomic DNA in a high molecular weight form. The lysate is moved through a porous filter to selectively trap the high molecular weight DNA on the filter. The DNA is released from the filter using an aqueous solution to form a solution containing substantially purified DNA, from which the DNA is recovered.
    Type: Grant
    Filed: November 13, 1990
    Date of Patent: February 16, 1993
    Assignee: Specialty Laboratories, Inc.
    Inventor: Kary B. Mullis
  • Syringe cap clamp tool
    Patent number: 4950015
    Abstract: A tool for gripping and manipulating an article, the tool being particularly useful in removing and replacing a cap on a needle of a hypodermic syringe. The tool is held and manipulable in one hand and includes a clamp element, an actuator movable between locked and release positions and a lock mechanism for locking the actuator in its locked position. The lock mechanism is easily depressed by the thumb to release the actuator and close the clamp element on the cap.
    Type: Grant
    Filed: January 23, 1989
    Date of Patent: August 21, 1990
    Assignee: Design Specialties Laboratories, Inc.
    Inventors: Umid R. Nejib, James J. Lennox, George M. Sarnecky, Larry C. Sickler