Abstract: Provided is a method including radiating first guide light, which guides a radiation position of a first pulsed beam, onto a suspicious tissue, receiving a first user input for instructing an output of the first pulsed beam while the first guide light is radiated, applying the first pulsed beam to the suspicious tissue to induce plasma ablation in a first target region corresponding to the radiation point of the first guide light, in response to the first user input, wherein the applying of the first pulsed beam is performed after obtaining first image data obtained by capturing an image of the first guide light and a tissue in a periphery the first guide light while the first guide light is radiated to the suspicious tissue, and obtaining target spectrum data on the plasma ablation, obtaining first disease information, and displaying the first image data and the first disease information.

Abstract: Provided is a disease information providing method including obtaining first image data obtained by image-capturing a body part and one or more suspicious tissues located in the body part, analyzing the first image data using an artificial neural network, detecting at least one target tissue from among the one or more suspicious tissues included in the first image data on the basis of the analysis result, requesting second image data on the at least one target tissue, obtaining the second image data obtained by image-capturing the at least one target tissue, obtaining disease information, wherein the second artificial neural network is trained to obtain a target result value related to the plurality of disease indicators for the target tissue included in the image data, and providing a disease score on the basis of the target result value.

Abstract: A method of measuring a concentration of an analyte in a bodily fluid sample is provided. The method includes introducing the bodily fluid sample containing the analyte into a test strip for a lateral flow assay (LFA) by a first volume to react the analyte with a metal nano probe for surface-enhanced Raman scattering (SERS), introducing a washing liquid into the test strip by a second volume after a first predetermined time interval has elapsed from the introduction of the bodily fluid sample, and performing a surface-enhanced Raman scattering (SERS)-based spectroscopic analysis on at least one of a test area and a control area of the test strip using a spectroscopic device.

Abstract: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.

Abstract: According to an embodiment of the present disclosure, there is provided a laser spectroscopy-based independent device, including: a spectrometer configured to measure a spectrum of generated light which is generated by a laser projected onto a sample; and a disease analysis module configured to determine whether there is lesion tissue by applying a lesion tissue detection learning model to a result of non-discrete spectrum measurement, which is measured by the spectrometer, wherein the spectrometer is configured to measure spectra of all generated light that is generated from a time when the laser is projected onto the sample.

Abstract: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.

Abstract: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.

Abstract: Disclosed herein are a diagnostic method using laser induced breakdown spectrum analysis and a diagnostic device for performing the same. The diagnostic device may include a laser projection module projecting a pulsed laser to a specimen, a light receiving module receiving a light generated by a plasma ablation induced at the specimen by the pulsed laser, a spectral member receiving and dividing the light generated by the plasma ablation; a sensor array including a plurality of sensors arranged to receive the divided light for each wavelength, and a controller obtaining spectrum data of the light generated by the plasma ablation from a specific exposure period, and determining whether or not the specimen is diseased based on the spectrum data of the light generated by the plasma ablation.

Abstract: Disclosed herein are a diagnostic method using laser induced breakdown spectrum analysis and a diagnostic device for performing the same. The diagnostic method may include projecting a pulsed laser to a suspicious specimen, obtaining first spectrum data on the light collected from the suspicious specimen, projecting the pulsed laser to a non-diseased specimen, obtaining second spectrum data on the light collected from the non-diseased specimen, and determining whether a disease is present in the suspicious specimen from a comparison value of the first spectrum data and the second spectrum data using an artificial neural network.

Abstract: The present disclosure relates to a method and a device for controlling a laser output. According to an embodiment, there are provided a method for controlling a laser output of a laser device, provided with a laser generator and a handpiece for radiating a laser generated at the laser generator onto a target, and a device performing the method. The method includes the steps of: measuring, by a plurality of distance sensors arranged along a circumference of one end of the handpiece from which the laser is outputted, distances between the plurality of distance sensors and the target; based on the distances between the distance sensors and the target, calculating an effective area which is a region of the target onto which the laser is really radiated; and increasing or reducing the laser output to radiate the laser onto the effective area with a predetermined energy density.

Abstract: According to one embodiment, a tip for a laser handpiece includes: a light radiating module configured to radiate a laser toward a target; and a light receiving module configured to receive at least a portion of light which is generated by the laser radiated onto the target as received light. The light radiating module includes: a base which has an inner space formed therein to allow the laser to pass therethrough; a fixing portion which is coupled to a lower portion of the base and has a penetrating hole formed therein to allow the laser to pass therethrough; and a module connecting member which is interposed and fixed between the base and the fixing portion.

Abstract: According to an embodiment, a tip for a diagnosis laser handpiece, coupled to a handpiece and used therein includes: a light emission module configured to emit a laser to a target; and a light adjustment module disposed on a path through which the laser emitted to the target travels. The light adjustment module is configured to adjust energy of the laser emitted to the target, and a focus size of the laser.

Abstract: A disease diagnosis and skin age measurement apparatus includes: a first light collection unit; a second light collection unit; a spectrometer configured to measure a spectrum of the light which is collected by the second light collection unit; a spectrum data comparison unit for disease diagnosis configured to compare the spectrum measured by the spectrometer and reference spectrum data for disease diagnosis; a CCD; an image data comparison unit configured to compare the digital image converted by the CCD and a reference image; a disease diagnosis unit configured to determine whether there is a disease in the body tissue; and/or a spectrum data comparison unit for skin age measurement configured to measure skin age by comparing a spectrum measured by the spectrometer and reference spectrum data for skin age measurement, wherein the light projected onto the body tissue is collimate light.