Abstract: A device for collecting exhaled breath allows a substantial air washing of the whole device which allows its re-use, after replacing the disposable portions. The device includes: a collecting terminal, having a mouthpiece grip which receives the exhaled breath; at least one collecting hole, for collecting a portion of exhaled breath from the collecting terminal, to be subjected to examination; least one discharge vent; and an aspirator device, which is connected to the at least one discharge vent of the collecting terminal through a respective discharge duct, and which includes at least one nanometric filter through which the exhaled breath sucked through is purified.