Patents Assigned to SPEPHARM AG
  • Publication number: 20240245653
    Abstract: A formulation comprising dantrolene, or a pharmaceutically acceptable salt thereof, and a cyclodextrin in a molar ratio of 1:3 to 1:12 and also comprising polyethylene glycol (PEG) with an average molecular weight in the range 1500 to 6000.
    Type: Application
    Filed: May 6, 2022
    Publication date: July 25, 2024
    Applicant: SPEPHARM AG
    Inventors: Samuel SMITH, Luke EDWARDS, Susanna SAUNDERS, Lorenzo MENCUCCINI
  • Publication number: 20240091198
    Abstract: The present invention relates to an aqueous composition comprising either dantrolene or a pharmaceutically acceptable salt thereof and a cyclodextrin derivative wherein the pH of the aqueous composition is greater than 7. Further, the present invention relates to a powder obtained by drying the inventive composition as well as a kit comprising said inventive powder.
    Type: Application
    Filed: November 7, 2023
    Publication date: March 21, 2024
    Applicant: SPEPHARM AG
    Inventors: Hervé Jean SCHWEBEL, Vincent ADAMO
  • Patent number: 11844782
    Abstract: An aqueous composition includes either dantrolene or a pharmaceutically acceptable salt thereof and a cyclodextrin derivative, with the pH of the aqueous composition greater than 7. A powder can be obtained by drying the composition. The powder can be included in a kit.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: December 19, 2023
    Assignee: SPEPHARM AG
    Inventors: Hervé Jean Schwebel, Vincent Adamo