Patents Assigned to SPHAERA PHARMA PTE. LTD.
  • Triazine compounds
    Patent number: 9630958
    Abstract: The present invention relates to novel triazine compounds of formula (1). The present invention also discloses compounds of formula I along with other pharmaceutical acceptable excipients and use of the compounds to modulate the PI3K/mTOR pathway.
    Type: Grant
    Filed: July 23, 2013
    Date of Patent: April 25, 2017
    Assignee: SPHAERA PHARMA PTE. LTD.
    Inventors: Sundeep Dugar, Dinesh Mahajan, Frank Hollinger Peter, Amit Sharma, Vinayak Tripathi, Bilash Kuila
  • Compounds, their synthesis and their uses
    Patent number: 9556156
    Abstract: The present invention discloses novel chemical compounds obtained by causing a covalent attachment of a modifying agent of the structure provided for formula 1, to a functional group or a heteroatom of a heterocyclic ring system in chemical compound with improved chemical and biological properties. Wherein: Y is DRUG-CO; DRUG-OCO; DRUG-NRCO, and X is selected from.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: January 31, 2017
    Assignee: SPHAERA PHARMA PTE LTD.
    Inventors: Sundeep Dugar, Frank Peter Hollinger, Dinesh Mahajan, Rhushikesh Chandrabhan Deokar
  • Triazine compounds
    Patent number: 9481670
    Abstract: The present invention relates to novel triazine compounds of formula (1), methods of their preparation, pharmaceutical compositions containing these compounds and the use of these compounds to treat proliferative disorders such as tumors and cancers and also other conditions and disorders related to or associated with dysregulation of PI3 Kinases, PI3 Kinase pathway, mTOR and/or the mTOR pathway.
    Type: Grant
    Filed: January 25, 2012
    Date of Patent: November 1, 2016
    Assignee: Sphaera Pharma PTE. Ltd.
    Inventors: Sundeep Dugar, Dinesh Mahajan, Chandraban Rhushikesh Deokar, Frank Peter Hollinger, Kamal Kishore Kapoor
  • Process for synthesis of polyphenols
    Patent number: 9428482
    Abstract: The present invention provides synthetic processes for preparing racemic and/or optically pure epicatechin, epigallocatechin and related polyphenols as such or as their variously functionalized derivatives. A principle objective of the disclosure is to provide a new and useful method of synthesis to obtain polyphenols in isomerically pure and/or racemic forms.
    Type: Grant
    Filed: January 24, 2012
    Date of Patent: August 30, 2016
    Assignee: SPHAERA PHARMA PTE. LTD.
    Inventors: Sundeep Dugar, Dinesh Mahajan, Peter Giannousis Pantelis, Vijay Singh, Kamal Kishore Kapoor
  • Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds
    Patent number: 9359376
    Abstract: The present invention relates to the synthesis and application of novel chiral/achiral substituted methyl formyl reagents to modify pharmaceutical agents and/or biologically active substances to modify the physicochemical, biological and/or pharmacokinetic properties of the resulting compounds from the unmodified original agent.
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: June 7, 2016
    Assignee: SPHAERA PHARMA PTE. LTD
    Inventors: Sundeep Dugar, Dinesh Mahajan, Frank Peter Hollinger
  • NOVEL COMPOUNDS, THEIR SYNTHESIS AND THEIR USES
    Publication number: 20150252027
    Abstract: The present invention discloses novel chemical compounds obtained by causing a covalent attachment of a modifying agent of the structure provided for formula 1, to a functional group or a heteroatom of a heterocyclic ring system in chemical compound with improved chemical and biological properties. Wherein: Y is DRUG-CO; DRUG-OCO; DRUG-NRCO, and X is selected from.
    Type: Application
    Filed: October 7, 2013
    Publication date: September 10, 2015
    Applicant: Sphaera Pharma Pte Ltd.
    Inventors: Sundeep Dugar, Frank Peter Hollinger, Dinesh Mahajan, Rhushikesh Chandrabhan Deokar
  • NOVEL TRIAZINE COMPOUNDS
    Publication number: 20150197515
    Abstract: The present invention relates to novel triazine compounds of formula (1). The present invention also discloses compounds of formula I along with other pharmaceutical acceptable excipients and use of the compounds to modulate the PI3K/mTOR pathway.
    Type: Application
    Filed: July 23, 2013
    Publication date: July 16, 2015
    Applicant: Sphaera Pharma Pte. Ltd.
    Inventors: Sundeep Dugar, Dinesh Mahajan, Frank Hollinger Peter, Amit Sharma, Vinayak Tripathi, Bilash Kuila
  • NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES
    Publication number: 20140100225
    Abstract: Novel compounds and their synthesis are described. Methods for using these compounds in the prevention or treatment of cancer, a bacterial infection or a viral infection in a subject are also described.
    Type: Application
    Filed: October 4, 2013
    Publication date: April 10, 2014
    Applicants: Inhibikase Therapeutics, Inc., Sphaera Pharma Pvt. Ltd., Sphaera Pharma Pte. Ltd.
    Inventors: Rhushikesh Chandrabhan Deokar, Sundeep Dugar, Dinesh Mahajan, Milton Henry Werner
  • NOVEL PROCESS FOR SYNTHESIS OF POLYPHENOLS
    Publication number: 20140031421
    Abstract: The present invention provides synthetic processes for preparing racemic and/or optically pure epicatechin, epigallocatechin and related polyphenols as such or as their variously functionalized derivatives. A principle objective of the disclosure is to provide a new and useful method of synthesis to obtain polyphenols in isomerically pure and/or racemic forms.
    Type: Application
    Filed: January 24, 2012
    Publication date: January 30, 2014
    Applicant: SPHAERA PHARMA PTE. LTD.
    Inventors: Sundeep Dugar, Dinesh Mahajan, Pantelis Peter Giannousis, Vijay Singh, Kamal Kishore Kapoor