Patents Assigned to Sphaera Pharma Pvt. Ltd.
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Patent number: 10752589Abstract: The present invention provides novel compounds with improved solubility and altered pharmacokinetic properties. The compounds of the present invention may be represented by Formula (I).Type: GrantFiled: March 14, 2017Date of Patent: August 25, 2020Assignee: SPHAERA PHARMA PVT. LTD.Inventors: Sundeep Dugar, Dinesh Mahajan, Somdutta Sen
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Publication number: 20190262347Abstract: The present invention discloses a novel, stable and synergistic combination of epicatechin with anti-cancer compounds. The present invention also discloses a composition comprising the novel combination of epicatechin with anti-cancer compounds along with other pharmaceutically acceptable excipients.Type: ApplicationFiled: November 1, 2017Publication date: August 29, 2019Applicant: SPHAERA PHARMA PVT. LTD.Inventor: Sundeep DUGAR
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Patent number: 10207993Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.Type: GrantFiled: August 10, 2017Date of Patent: February 19, 2019Assignees: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTREInventors: Sundeep Dugar, Dinesh Mahajan, Santosh Kumar Rai, Kanury Rao, Varshneya Singh
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Patent number: 10100012Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.Type: GrantFiled: June 1, 2015Date of Patent: October 16, 2018Assignees: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTREInventors: Sundeep Dugar, Dinesh Mahajan, Santosh Kumar Rai, Kanury Rao, Varshneya Singh
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Patent number: 9975869Abstract: The present invention provides novel analogs of epicatechin and related polyphenols, their variously functionalized derivatives, process for preparation of the same, composition comprising these compounds and their method of use.Type: GrantFiled: April 4, 2014Date of Patent: May 22, 2018Assignee: SPHAERA PHARMA PVT. LTD.Inventors: Sundeep Dugar, Dinesh Mahajan, Kumar Santosh Rai, Sarbjit Singh, Ishwar Rakesh Patil
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Publication number: 20170334851Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.Type: ApplicationFiled: August 10, 2017Publication date: November 23, 2017Applicants: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTREInventors: Sundeep DUGAR, Dinesh MAHAJAN, Santosh Kumar RAI, Kanury RAO, Varshneya SINGH
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Publication number: 20170183305Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.Type: ApplicationFiled: June 1, 2015Publication date: June 29, 2017Applicants: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTREInventors: Sundeep DUGAR, Dinesh MAHAJAN, Santosh Kumar RAI, Kanury RAO, Varshneya SINGH
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Publication number: 20170158730Abstract: The present invention relates to novel steroidal compounds of formula (I), process for preparation of the same and composition comprising these compounds.Type: ApplicationFiled: July 23, 2015Publication date: June 8, 2017Applicant: SPHAERA PHARMA PVT. LTD.Inventors: Sundeep DUGAR, Dinesh MAHAJAN, George Frederick SCHREINER
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Patent number: 9556140Abstract: A process for synthesis of enatiomerically pure or enatiomerically enriched or racemic mixture of (+ and/or ?) epicatechin and its intermediates, comprising the steps of: (i) obtaining penta-protected quercetin; (ii) reducing the penta-protected quercetin obtained from step (i); (iii) optionally deprotecting the compound of step (ii); (iv) reducing the compound obtained from step (ii) or step (iii) in the presence of a chiral/achiral reducing agent to obtain a chiral intermediate; (v) deprotecting and/or hydrogenation of the chiral intermediate obtained from step (iv) to obtain (?)-epicatechin; (vi) optionally simultaneously deprotecting and by drogenation of the compound obtained from step (ii) to obtain racemic epicatechin.Type: GrantFiled: January 27, 2014Date of Patent: January 31, 2017Assignee: Sphaera Pharma Pvt. Ltd.Inventors: Sundeep Dugar, Dinesh Mahajan, Kumar Santosh Rai, Vinayak Tripathi, Ishwar Rakesh Patil
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Publication number: 20160039781Abstract: The present invention provides novel analogues of epicatechin and related polyphenols, their variously functionalized derivatives, process for preparation of the same, composition comprising these compounds and their method of use.Type: ApplicationFiled: April 4, 2014Publication date: February 11, 2016Applicant: Sphaera Pharma Pvt. Ltd.Inventors: Sundeep DUGAR, Dinesh MAHAJAN, Kumar Santosh RAI, Sarbjit SINGH, Ishwar Rakesh PATIL
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Publication number: 20140100225Abstract: Novel compounds and their synthesis are described. Methods for using these compounds in the prevention or treatment of cancer, a bacterial infection or a viral infection in a subject are also described.Type: ApplicationFiled: October 4, 2013Publication date: April 10, 2014Applicants: Inhibikase Therapeutics, Inc., Sphaera Pharma Pvt. Ltd., Sphaera Pharma Pte. Ltd.Inventors: Rhushikesh Chandrabhan Deokar, Sundeep Dugar, Dinesh Mahajan, Milton Henry Werner