Patents Assigned to Sphaera Pharma Pvt. Ltd.
  • Patent number: 10752589
    Abstract: The present invention provides novel compounds with improved solubility and altered pharmacokinetic properties. The compounds of the present invention may be represented by Formula (I).
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: August 25, 2020
    Assignee: SPHAERA PHARMA PVT. LTD.
    Inventors: Sundeep Dugar, Dinesh Mahajan, Somdutta Sen
  • Publication number: 20190262347
    Abstract: The present invention discloses a novel, stable and synergistic combination of epicatechin with anti-cancer compounds. The present invention also discloses a composition comprising the novel combination of epicatechin with anti-cancer compounds along with other pharmaceutically acceptable excipients.
    Type: Application
    Filed: November 1, 2017
    Publication date: August 29, 2019
    Applicant: SPHAERA PHARMA PVT. LTD.
    Inventor: Sundeep DUGAR
  • Patent number: 10207993
    Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: February 19, 2019
    Assignees: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTRE
    Inventors: Sundeep Dugar, Dinesh Mahajan, Santosh Kumar Rai, Kanury Rao, Varshneya Singh
  • Patent number: 10100012
    Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: October 16, 2018
    Assignees: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTRE
    Inventors: Sundeep Dugar, Dinesh Mahajan, Santosh Kumar Rai, Kanury Rao, Varshneya Singh
  • Patent number: 9975869
    Abstract: The present invention provides novel analogs of epicatechin and related polyphenols, their variously functionalized derivatives, process for preparation of the same, composition comprising these compounds and their method of use.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: May 22, 2018
    Assignee: SPHAERA PHARMA PVT. LTD.
    Inventors: Sundeep Dugar, Dinesh Mahajan, Kumar Santosh Rai, Sarbjit Singh, Ishwar Rakesh Patil
  • Publication number: 20170334851
    Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.
    Type: Application
    Filed: August 10, 2017
    Publication date: November 23, 2017
    Applicants: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTRE
    Inventors: Sundeep DUGAR, Dinesh MAHAJAN, Santosh Kumar RAI, Kanury RAO, Varshneya SINGH
  • Publication number: 20170183305
    Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.
    Type: Application
    Filed: June 1, 2015
    Publication date: June 29, 2017
    Applicants: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTRE
    Inventors: Sundeep DUGAR, Dinesh MAHAJAN, Santosh Kumar RAI, Kanury RAO, Varshneya SINGH
  • Publication number: 20170158730
    Abstract: The present invention relates to novel steroidal compounds of formula (I), process for preparation of the same and composition comprising these compounds.
    Type: Application
    Filed: July 23, 2015
    Publication date: June 8, 2017
    Applicant: SPHAERA PHARMA PVT. LTD.
    Inventors: Sundeep DUGAR, Dinesh MAHAJAN, George Frederick SCHREINER
  • Patent number: 9556140
    Abstract: A process for synthesis of enatiomerically pure or enatiomerically enriched or racemic mixture of (+ and/or ?) epicatechin and its intermediates, comprising the steps of: (i) obtaining penta-protected quercetin; (ii) reducing the penta-protected quercetin obtained from step (i); (iii) optionally deprotecting the compound of step (ii); (iv) reducing the compound obtained from step (ii) or step (iii) in the presence of a chiral/achiral reducing agent to obtain a chiral intermediate; (v) deprotecting and/or hydrogenation of the chiral intermediate obtained from step (iv) to obtain (?)-epicatechin; (vi) optionally simultaneously deprotecting and by drogenation of the compound obtained from step (ii) to obtain racemic epicatechin.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: January 31, 2017
    Assignee: Sphaera Pharma Pvt. Ltd.
    Inventors: Sundeep Dugar, Dinesh Mahajan, Kumar Santosh Rai, Vinayak Tripathi, Ishwar Rakesh Patil
  • Publication number: 20160039781
    Abstract: The present invention provides novel analogues of epicatechin and related polyphenols, their variously functionalized derivatives, process for preparation of the same, composition comprising these compounds and their method of use.
    Type: Application
    Filed: April 4, 2014
    Publication date: February 11, 2016
    Applicant: Sphaera Pharma Pvt. Ltd.
    Inventors: Sundeep DUGAR, Dinesh MAHAJAN, Kumar Santosh RAI, Sarbjit SINGH, Ishwar Rakesh PATIL
  • Publication number: 20140100225
    Abstract: Novel compounds and their synthesis are described. Methods for using these compounds in the prevention or treatment of cancer, a bacterial infection or a viral infection in a subject are also described.
    Type: Application
    Filed: October 4, 2013
    Publication date: April 10, 2014
    Applicants: Inhibikase Therapeutics, Inc., Sphaera Pharma Pvt. Ltd., Sphaera Pharma Pte. Ltd.
    Inventors: Rhushikesh Chandrabhan Deokar, Sundeep Dugar, Dinesh Mahajan, Milton Henry Werner