Abstract: The invention provides a non-particulate cross-linked poly-?-lysine polymer. The poly-?-lysine and cross linker are linked by amide bonds and may the cross linker has at least two functional groups capable of reacting with an alpha carbon amine of poly-?-lysine. The polymer is suitably insoluble in water and other solvents and is provided in macro form for example a sheet, article or fiber. The macro form polymer is useful in a wide range of applications including wound treatment, as a medical diagnostic comprising a particulate support and a functional material bound or retained by the support and solid phase synthesis of peptides, oligonucleotides, oligosaccharides, immobilization of species, cell culturing and in chromatographic separation.

Abstract: The invention provides a cross-linked poly-?-lysine polymer. The poly-?-lysine and cross linker are linked by amide bonds and may the cross linker has at least two functional groups capable of reacting with an alpha carbon amine of poly-?-lysine. The polymer is suitably insoluble in water and other solvents and is provided in particulate form. The invention provides a particulate support comprising the cross-linked poly-?-lysine polymer and the polymer may provide the particle itself or be coated on a particle for example silica. The polymer is useful in a wide range of applications including wound treatment, as a medical diagnostic comprising a particulate support and a functional material bound or retained by the support and solid phase synthesis of peptides, oligonucleotides, oligosaccharides, immobilisation of species, cell culturing and in chromatographic separation.

Abstract: The invention provides a non-particulate cross-linked poly-?-lysine polymer. The poly-?-lysine and cross linker are linked by amide bonds and may the cross linker has at least two functional groups capable of reacting with an alpha carbon amine of poly-?-lysine. The polymer is suitably insoluble in water and other solvents and is provided in macro form for example a sheet, article or fibre. The macro form polymer is useful in a wide range of applications including wound treatment, as a medical diagnostic comprising a particulate support and a functional material bound or retained by the support and solid phase synthesis of peptides, oligonucleotides, oligosaccharides, immobilisation of species, cell culturing and in chromatographic separation.

Abstract: A 3-dimensional porous polymeric structure comprising a porous polymer structure optionally with particles within the pores of the polymer and wherein the pores have a narrow pore-size distribution. The structure may be made by closely packing particles in a zone to provide a 3-dimensional array, contacting a polymerisable monomer with the array such that the composition fills interstitial spaces between the particles and effecting polymerisation of the monomer whereby a polymer structure is formed around the particles and optionally removing the particles from the structure. The 3-dimensional porous structure may be used in solid phase synthesis, immobilisation, cell culturing and preparation of a stationary phase for chromatographic separation, as an absorbent, an insulating material or in tissue regeneration.

Abstract: A particulate body having a hollow particle and a surface polymer disposed on the outside of the hollow particle and suitable for use in solid phase synthesis, especially production of peptides and oligonucleotides. The particulate body may be used as a chromatography stationary phase column and the buoyancy of the body allows the column to be packed efficiently from the bottom reducing the risk of damage to the stationary phase. The buoyancy of the particulate body may also allow species for example a catalyst to be suspended in a liquid phase to allow reactions, for example hydrolysis of vegetable oil and esterification to produce biodiesel to be carried out with a reduced risk of catalyst loss from a reaction zone.