Abstract: A drainage spigot guard may be configured to disinfect a spigot from a urinary catheter. The drainage spigot guard may include a shell with an interior cavity shaped to receive the spigot. The drainage spigot guard may further include a first disinfectant swab within the interior cavity. The first disinfectant swab may be positioned to disinfect at least part of the spigot in response to insertion of the spigot into the interior cavity. The shell may have an exterior shape configured to be received within a spigot retainer on a urinary catheter bag attached to the spigot.