Patents Assigned to SPIROCHEM AG
  • Method of preparing substituted bicyclo[1.1.1] pentanes
    Patent number: 10513483
    Abstract: A process for the preparation of a class of molecules, namely bicyclo[1.1.1]pentanes and derivatives thereof by reaction of [1.1.1]propellane with a variety of reagents under irradiation and/or in the presence of radical initiators to obtain bicyclo[1.1.1]pentanes asymmetrically substituted at position 1 and 3, which are useful as intermediates for the preparation of asymmetrically 1,3-disubstituted bicyclo[1.1.1]pentane derivatives and various physiologically active substances or materials containing these structures.
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: December 24, 2019
    Assignee: SPIROCHEM AG
    Inventors: Yoshikazu Suzuki, Daniel Jimenez-Teja, Christophe Salomé, Thomas Fessard