Patents Assigned to SPIROCHM AG
  • METHOD OF PREPARING SUBSTITUTED BICYCLO[1.1.1] PENTANES
    Publication number: 20190092714
    Abstract: A process for the preparation of a class of molecules, namely bicyclo[1.1.1]pentanes and derivatives thereof by reaction of [1.1.1]propellane with a variety of reagents under irradiation and/or in the presence of radical initiators to obtain bicyclo[1.1.1]pentanes asymmetrically substituted at position 1 and 3, which are useful as intermediates for the preparation of asymmetrically 1,3-disubstituted bicyclo[1.1.1]pentane derivatives and various physiologically active substances or materials containing these structures.
    Type: Application
    Filed: March 14, 2017
    Publication date: March 28, 2019
    Applicant: SPIROCHM AG
    Inventors: Yoshikazu SUZUKI, Daniel JIMENEZ-TEJA, Christophe SALOMÉ, Thomas FESSARD