Abstract: The present invention relates generally to vaccine strains of Brachyspira hyodysenteriae. In particular, the present invention relates to isolated live vaccine strains of B. hyodysenteriae lacking one or more virulence factors. The present invention also relates to methods of identifying and preparing vaccine strains, as well as vaccine compositions against diarrhoeal diseases and methods and kits for diagnosing same.
Type:
Grant
Filed:
November 13, 2009
Date of Patent:
April 21, 2015
Assignee:
Spirogene Pty Ltd
Inventors:
David J. Hampson, Tom La, Matthew I. Bellgard, Nyree D. Phillips
Abstract: Novel polynucleotide and amino acids of Brachyspira hyodysenteriae are described. These sequences are useful for diagnosis of B. hyodysenteriae disease in animals and as a therapeutic treatment or prophylactic treatment of B. hyodysenteriae disease in animals. These sequences may also be useful for diagnostic and therapeutic and/or prophylactic treatment of diseases in animals caused by other Brachyspira species.
Type:
Application
Filed:
February 27, 2009
Publication date:
March 17, 2011
Applicant:
SPIROGENE PTY LTD
Inventors:
David J. Hampson, Tom La, Matthew I. Bellgard, Nyree D. Phillips
Abstract: Novel polynucleotide and amino acids of Brachyspira hyodysenteriae are described. These sequences are useful for diagnosis of B. hyodysenteriae disease in animals and as a therapeutic treatment or prophylactic treatment of B. hyodysenteriae disease in animals.
Type:
Application
Filed:
March 26, 2009
Publication date:
March 17, 2011
Applicant:
SPIROGENE PTY LTD
Inventors:
David J. Hampson, Tom La, Matthew I. Bellgard, Nyree D. Phillips
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