Patents Assigned to Spirox, Inc.
  • Patent number: 11957448
    Abstract: A diagnostic tool and methods of using the tool are provided to quantify an amount of nasal collapse in a patient. The diagnostic tool includes a mask with an endoscope port and an opening to allow air flow, an endoscope with a camera adapted to take an image of the nasal valve, and an air flow sensor adapted to measure an inhalation rate of the patient. The diagnostic tool can quantify a size difference between the nasal valve during inhalation and zero flow by calculating a percentage difference in an area or one or more dimensions of the nasal valve during inhalation and zero flow.
    Type: Grant
    Filed: April 4, 2023
    Date of Patent: April 16, 2024
    Assignee: Spirox, Inc.
    Inventors: Scott J. Baron, Michael H. Rosenthal
  • Patent number: 11890186
    Abstract: Described are implants for placing in a body, tools for delivering the implants, and systems and methods for using implants and tools for placing in a body and more particularly to nasal implants, tools for delivering nasal implants, and systems and methods for using such implants and tools. A tool may include a hand-held implant delivery device that cuts, holds, moves, orients, inserts, or shapes an implant. An implant may be a biodegradable, longitudinal implant that may be oriented for implantation by an implant delivery device.
    Type: Grant
    Filed: February 1, 2020
    Date of Patent: February 6, 2024
    Assignee: Spirox, Inc.
    Inventors: Iyad S. Saidi, Michael H. Rosenthal, Donald A. Gonzales, J. Cameron Loper, Marcus A. Hadley, Jamie L. Ingram, Cheng Q. Ren, Charles P. Luddy, Leon A. Marucchi, Bruce C. Gray, R. Andrew Carlton
  • Patent number: 11877771
    Abstract: A nasal implant delivery tool includes an inner handle, an outer handle, a needle, and a push rod. The inner handle includes a loading chamber configured to receive a nasal implant. The outer handle is configured to move axially relative to the inner handle. The needle extends distally from the inner handle and has a central lumen and a distal opening. The push rod is configured to move the nasal implant from the loading chamber, through the central lumen, and out the distal opening of the needle. The push rod is coupled to the outer handle such that the push rod moves axially relative to the inner handle when the outer handle is moved axially relative to the inner handle. Also described herein are nasal implant guides and methods of using nasal implant delivery tools and nasal implant guides.
    Type: Grant
    Filed: August 8, 2022
    Date of Patent: January 23, 2024
    Assignee: Spirox, Inc.
    Inventors: Michael H. Rosenthal, Scott J. Baron, Brian J. Domecus, Michael S. Mirizzi, Sergio Salinas
  • Patent number: 11806265
    Abstract: The present invention relates to apparatus ad methods for correcting nasal valve collapse comprising a device configured for suspending a nasal valve, the device comprising a body portion comprising a proximal end, a distal end, and a plurality of barbs, wherein the body portion is configured to be inserted through or underneath the upper lateral cartilage of a patient and wherein the plurality of barbs are configured to engage a soft tissue overlying a bony tissue proximal to the upper lateral cartilage, and a head portion coupled to the proximal end of the body portion wherein the head portion is configured to engage the upper lateral cartilage of the patient when the plurality of barbs are engaged with the soft tissue overlying the bony tissue proximal to the upper lateral cartilage.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: November 7, 2023
    Assignee: Spirox, Inc.
    Inventors: Donald A. Gonzales, Christopher M. Revell
  • Patent number: 11737865
    Abstract: Described are implants for placing in a body, tools for delivering the implants, and systems and methods for using implants and tools for placing in a body and more particularly to nasal implants, tools for delivering nasal implants, and systems and methods for using such implants and tools. A tool may include a hand-held implant delivery device that holds, moves, orients, inserts, or shapes an implant. An implant may be a biodegradable, longitudinal implant that may be oriented for implantation by an implant delivery device.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: August 29, 2023
    Assignee: Spirox, Inc.
    Inventors: Scott J. Baron, Michael H. Rosenthal, Brian Domecus, Piyush Arora, Michael Stephan Mirizzi, Rohit Kulbhushan Girotra
  • Patent number: 11642043
    Abstract: A diagnostic tool and methods of using the tool are provided to quantify an amount of nasal collapse in a patient. The diagnostic tool includes a mask with an endoscope port and an opening to allow air flow, an endoscope with a camera adapted to take an image of the nasal valve, and an air flow sensor adapted to measure an inhalation rate of the patient. The diagnostic tool can quantify a size difference between the nasal valve during inhalation and zero flow by calculating a percentage difference in an area or one or more dimensions of the nasal valve during inhalation and zero flow.
    Type: Grant
    Filed: March 28, 2021
    Date of Patent: May 9, 2023
    Assignee: Spirox, Inc.
    Inventors: Scott J. Baron, Michael H. Rosenthal
  • Patent number: 11590329
    Abstract: In another example, a bioresorbable implant for use in a nasal region includes one or more bioresorbable polymers, and a pharmaceutical composition coupled to the one or more bioresorbable polymers. A release rate of the pharmaceutical composition is related to a degradation rate of the one or more bioresorbable polymers.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: February 28, 2023
    Assignee: Spirox, Inc.
    Inventors: Gene Michal, Daniel L. Cox, Piyush Arora, Michael S. Mirizzi, Scott Baron
  • Patent number: 11576770
    Abstract: Described are implants for placing in a body, tools for delivering the implants, and systems and methods for using implants and tools for placing in a body and more particularly to nasal implants, tools for delivering nasal implants, and systems and methods for using such implants and tools.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: February 14, 2023
    Assignee: Spirox, Inc.
    Inventors: Michael H. Rosenthal, Brian Domecus, Piyush Arora, Halil I. Karabey, Gilbert Laroya, Michael S. Mirizzi, Scott J. Baron
  • Patent number: 11464542
    Abstract: A nasal implant delivery tool includes an inner handle, an outer handle, a needle, and a push rod. The inner handle includes a loading chamber configured to receive a nasal implant. The outer handle is configured to move axially relative to the inner handle. The needle extends distally from the inner handle and has a central lumen and a distal opening. The push rod is configured to move the nasal implant from the loading chamber, through the central lumen, and out the distal opening of the needle. The push rod is coupled to the outer handle such that the push rod moves axially relative to the inner handle when the outer handle is moved axially relative to the inner handle. Also described herein are nasal implant guides and methods of using nasal implant delivery tools and nasal implant guides.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: October 11, 2022
    Assignee: Spirox, Inc.
    Inventors: Michael H. Rosenthal, Scott J. Baron, Brian J. Domecus, Michael S. Mirizzi, Sergio Salinas
  • Patent number: 11241306
    Abstract: Nasal implants are provided that have a planar type profile with open spaces through portions of the planar type profile. The nasal implant can be compressible along one or more dimensions of the nasal implant, such as the width and length of the planar type profile. Delivery tools for deploying the nasal implants within the nasal tissue are also provided. Methods for deploying the nasal implants within the nasal tissue of the patient are also provided.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: February 8, 2022
    Assignee: Spirox, Inc.
    Inventors: Michael H. Rosenthal, Scott Jeffrey Baron, Donald A. Gonzales, Piyush Arora, Michael S. Mirizzi, Pankaj Rathi, Christopher Marquis
  • Patent number: 11071623
    Abstract: Nasal implants and nasal implant delivery tools are described herein. The nasal implants and tools can be used to deliver the implant in a minimally invasive way. The delivery tools can be adapted to separate the upper lateral cartilage from the septum and to place an implant between the septum and the upper lateral cartilage. The implant can be configured to be placed between the upper lateral cartilage and the septum. The implant system can include a first longitudinal body adapted to engage with upper lateral cartilage and the septum on a first side of the septum and a second longitudinal body adapted to engage with upper lateral cartilage and the septum on a second side of the septum.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: July 27, 2021
    Assignee: Spirox, Inc.
    Inventors: Michael H. Rosenthal, Donald A. Gonzales, Brian Domecus, Scott J. Baron, Sergio Salinas
  • Patent number: 10993800
    Abstract: Described are implants for placing in a body, tools for delivering the implants, and systems and methods for using implants and tools for placing in a body and more particularly to nasal implants, tools for delivering nasal implants, and systems and methods for using such implants and tools. A tool may include a hand-held implant delivery device that holds, moves, orients, inserts, or shapes an implant. An implant may be a biodegradable, longitudinal implant that may be oriented for implantation by an implant delivery device.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: May 4, 2021
    Assignee: Spirox, Inc.
    Inventors: Scott J. Baron, Michael H. Rosenthal, Brian Domecus, Piyush Arora, Michael Stephan Mirizzi, Rohit Kulbhushan Girotra
  • Patent number: 10987024
    Abstract: A diagnostic tool and methods of using the tool are provided to quantify an amount of nasal collapse in a patient. The diagnostic tool includes a mask with an endoscope port and an opening to allow air flow, an endoscope with a camera adapted to take an image of the nasal valve, and an air flow sensor adapted to measure an inhalation rate of the patient. The diagnostic tool can quantify a size difference between the nasal valve during inhalation and zero flow by calculating a percentage difference in an area or one or more dimensions of the nasal valve during inhalation and zero flow.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: April 27, 2021
    Assignee: Spirox, Inc.
    Inventors: Scott J. Baron, Michael H. Rosenthal
  • Patent number: 10980631
    Abstract: Described are implants for placing in a body, tools for delivering the implants, and systems and methods for using implants and tools for placing in a body and more particularly to nasal implants, tools for delivering nasal implants, and systems and methods for using such implants and tools. A tool may include a hand-held implant delivery device that holds, moves, orients, inserts, or shapes an implant. An implant may be a biodegradable, longitudinal implant that may be oriented for implantation by an implant delivery device.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: April 20, 2021
    Assignee: Spirox, Inc.
    Inventors: Michael H. Rosenthal, Scott J. Baron, Donald A. Gonzales, Iyad S. Saidi
  • Patent number: 10786383
    Abstract: The present invention relates to apparatus and methods for correcting nasal valve collapse comprising a device configured for suspending a nasal valve, the device comprising a body portion comprising a proximal end, a distal end, and a plurality of barbs, wherein the body portion is configured to be inserted through or underneath the upper lateral cartilage of a patient and wherein the plurality of barbs are configured to engage a soft tissue overlying a bony tissue proximal to the upper lateral cartilage, and a head portion coupled to the proximal end of the body portion wherein the head portion is configured to engage the upper lateral cartilage of the patient when the plurality of barbs are engaged with the soft tissue overlying the bony tissue proximal to the upper lateral cartilage.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: September 29, 2020
    Assignee: Spirox, Inc.
    Inventors: Donald A. Gonzales, Christopher M. Revell
  • Patent number: 10603163
    Abstract: A method for non-surgically treating an internal nasal valve of a patient comprising, injecting a working device into the internal nasal valve of the patient, wherein the injected working device in the nasal tissue causes an alteration of an internal or external nasal valve. A device introduced by injection into the nose, allowing for structural support or filling of defects in the nose, and causing a change in external shape of the nose. The device and inserts and implants described also have use in cosmetic applications relating to the facial tissue.
    Type: Grant
    Filed: July 15, 2014
    Date of Patent: March 31, 2020
    Assignee: Spirox, Inc.
    Inventor: Iyad S. Saidi
  • Patent number: 10588740
    Abstract: Described are implants for placing in a body, tools for delivering the implants, and systems and methods for using implants and tools for placing in a body and more particularly to nasal implants, tools for delivering nasal implants, and systems and methods for using such implants and tools. A tool may include a hand-held implant delivery device that cuts, holds, moves, orients, inserts, or shapes an implant. An implant may be a biodegradable, longitudinal implant that may be oriented for implantation by an implant delivery device.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: March 17, 2020
    Assignee: SPIROX, INC .
    Inventors: Iyad S. Saidi, Michael H. Rosenthal, Donald A. Gonzales, J. Cameron Loper, Marcus A. Hadley, Jamie L. Ingram, Cheng Q. Ren, Charles P. Luddy, Leon A. Marucchi, Bruce C. Gray, R. Andrew Carlton
  • Patent number: 10398545
    Abstract: Described are implants for placing in a body, tools for delivering the implants, and systems and methods for using implants and tools for placing in a body and more particularly to nasal implants, tools for delivering nasal implants, and systems and methods for using such implants and tools. A tool may include a hand-held implant delivery device that holds, moves, orients, inserts, or shapes an implant. An implant may be a biodegradable, longitudinal implant that may be oriented for implantation by an implant delivery device.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: September 3, 2019
    Assignee: Spirox, Inc.
    Inventors: Michael H. Rosenthal, Scott J. Baron, Donald A. Gonzales, Iyad S. Saidi
  • Publication number: 20190246951
    Abstract: A diagnostic tool and methods of using the tool are provided to quantify an amount of nasal collapse in a patient. The diagnostic tool includes a mask with an endoscope port and an opening to allow air flow, an endoscope with a camera adapted to take an image of the nasal valve, and an air flow sensor adapted to measure an inhalation rate of the patient. The diagnostic tool can quantify a size difference between the nasal valve during inhalation and zero flow by calculating a percentage difference in an area or one or more dimensions of the nasal valve during inhalation and zero flow.
    Type: Application
    Filed: September 15, 2017
    Publication date: August 15, 2019
    Applicant: SPIROX, INC.
    Inventors: Scott J. Baron, Michael H. Rosenthal
  • Publication number: 20190240005
    Abstract: Nasal implants and nasal implant delivery tools are described herein. The nasal implants and tools can be used to deliver the implant in a minimally invasive way. The delivery tools can be adapted to separate the upper lateral cartilage from the septum and to place an implant between the septum and the upper lateral cartilage. The implant can be configured to be placed between the upper lateral cartilage and the septum. The implant system can include a first longitudinal body adapted to engage with upper lateral cartilage and the septum on a first side of the septum and a second longitudinal body adapted to engage with upper lateral cartilage and the septum on a second side of the septum.
    Type: Application
    Filed: November 3, 2017
    Publication date: August 8, 2019
    Applicant: SPIROX, INC.
    Inventors: Michael H. Rosenthal, Donald A. Gonzales, Brian DOMECUS, Scott J. BARON, Sergio SALINAS